Next Article in Journal
Extranodal NK/T-Cell Lymphoma Presenting with Primary Cardiac Involvement
Previous Article in Journal
Two Cases of Aspergillus Endocarditis in Non Neutropenic Children on Chemotherapy for Acute Lymphoblastic Leukaemia
 
 
Search for Articles:
Title / Keyword
Author / Affiliation / Email
Journal
Article Type
 
 
Advanced Search
 
Section
Special Issue
Volume
Issue
Number
Page
 
Journals
Hematology Reports
Volume 3
Issue 1
10.4081/hr.2011.e8
hematolrep-logo
Submit to this Journal Review for this Journal Propose a Special Issue
► Article Menu

Article Menu

share Share announcement Help format_quote Cite question_answer Discuss in SciProfiles thumb_up
...
Endorse textsms
...
Comment
Hematology Reports is published by MDPI from Volume 14 Issue 1 (2022). Previous articles were published by another publisher in Open Access under a CC-BY (or CC-BY-NC-ND) licence, and they are hosted by MDPI on mdpi.com as a courtesy and upon agreement with PAGEPress.
first_page
settings
Order Article Reprints
Font Type:
Arial Georgia Verdana
Font Size:
Aa Aa Aa
Line Spacing:
Column Width:
Background:
Article

Powered Bone Marrow Biopsy Procedures Produce Larger Core Specimens, with Less Pain, in Less Time Than with Standard Manual Devices

by
Larry J. Miller
1,
Thomas E. Philbeck
1,*,
Diana F. Montez
1,
Tatiana A. Puga
1,
Kim E. Brodie
1,
Stephen C. Cohen
2,
Cathy Spadaccini
3,
Ronan Swords
4 and
Andrew J. Brenner
4
1
Vidacare Corporatio, 4350 Lockhill Selma Road, Shavano Park, TX 78249, USA
2
Medical Therapy & Research, San Antonio, TX 78217, USA
3
Ameripath, San Antonio, TX 78207, USA
4
University of Texas Health Science Center at San Antonio, San Antonio, TX 78229, USA
*
Author to whom correspondence should be addressed.
Hematol. Rep. 2011, 3(1), e8; https://doi.org/10.4081/hr.2011.e8
Submission received: 31 May 2011 / Revised: 25 June 2011 / Accepted: 29 June 2011 / Published: 18 July 2011

Abstract

Bone marrow sampling remains essential in the evaluation of hematopoietic and many non-hematopoietic disorders. One common limitation to these procedures is the discomfort experienced by patients. To address whether a Powered biopsy system could reduce discomfort while providing equivalent or better results, we performed a randomized trial in adult volunteers. Twenty-six subjects underwent bilateral biopsies with each device. Core samples were obtained in 66.7% of Manual insertions; 100% of Powered insertions (p = 0.002). Initial mean biopsy core lengths were 11.1 ± 4.5 mm for the Manual device; 17.0 ± 6.8 mm for the Powered device (p < 0.005). Pathology assessment for the Manual device showed a mean length of 6.1 ± 5.6 mm, width of 1.0 ± 0.7 mm, and volume of 11.0 ± 10.8 mm3. Powered device measurements were mean length of 15.3 ± 6.1 mm, width of 2.0 ± 0.3 mm, and volume of 49.1 ± 21.5 mm3 (p < 0.001). The mean time to core ejection was 86 seconds for Manual device; 47 seconds for the Powered device (p < 0.001). The mean second look overall pain score was 33.3 for the Manual device; 20.9 for the Powered (p = 0.039). We conclude that the Powered biopsy device produces superior sized specimens, with less overall pain, in less time.
Keywords: bone marrow biopsy; core biopsy; trephine biopsy; powered biopsy bone marrow biopsy; core biopsy; trephine biopsy; powered biopsy

Share and Cite

MDPI and ACS Style

Miller, L.J.; Philbeck, T.E.; Montez, D.F.; Puga, T.A.; Brodie, K.E.; Cohen, S.C.; Spadaccini, C.; Swords, R.; Brenner, A.J. Powered Bone Marrow Biopsy Procedures Produce Larger Core Specimens, with Less Pain, in Less Time Than with Standard Manual Devices. Hematol. Rep. 2011, 3, e8. https://doi.org/10.4081/hr.2011.e8

AMA Style

Miller LJ, Philbeck TE, Montez DF, Puga TA, Brodie KE, Cohen SC, Spadaccini C, Swords R, Brenner AJ. Powered Bone Marrow Biopsy Procedures Produce Larger Core Specimens, with Less Pain, in Less Time Than with Standard Manual Devices. Hematology Reports. 2011; 3(1):e8. https://doi.org/10.4081/hr.2011.e8

Chicago/Turabian Style

Miller, Larry J., Thomas E. Philbeck, Diana F. Montez, Tatiana A. Puga, Kim E. Brodie, Stephen C. Cohen, Cathy Spadaccini, Ronan Swords, and Andrew J. Brenner. 2011. "Powered Bone Marrow Biopsy Procedures Produce Larger Core Specimens, with Less Pain, in Less Time Than with Standard Manual Devices" Hematology Reports 3, no. 1: e8. https://doi.org/10.4081/hr.2011.e8

APA Style

Miller, L. J., Philbeck, T. E., Montez, D. F., Puga, T. A., Brodie, K. E., Cohen, S. C., Spadaccini, C., Swords, R., & Brenner, A. J. (2011). Powered Bone Marrow Biopsy Procedures Produce Larger Core Specimens, with Less Pain, in Less Time Than with Standard Manual Devices. Hematology Reports, 3(1), e8. https://doi.org/10.4081/hr.2011.e8

Article Metrics

Back to TopTop