Next Article in Journal
Long-Term Complete Remission of Early Hematological Relapse after Discontinuation of Immunosuppressants Following Allogeneic Transplantation for Sezary Syndrome
Previous Article in Journal
XLIII Congresso Nazionale AIEOP|Bologna, 27–29 Maggio 2018
 
 
Search for Articles:
Title / Keyword
Author / Affiliation / Email
Journal
Article Type
 
 
Advanced Search
 
Section
Special Issue
Volume
Issue
Number
Page
 
Journals
Hematology Reports
Volume 10
Issue 2
10.4081/hr.2018.7040
hematolrep-logo
Submit to this Journal Review for this Journal Propose a Special Issue
► Article Menu

Article Menu

share Share announcement Help format_quote Cite question_answer Discuss in SciProfiles thumb_up
...
Endorse textsms
...
Comment
Hematology Reports is published by MDPI from Volume 14 Issue 1 (2022). Previous articles were published by another publisher in Open Access under a CC-BY (or CC-BY-NC-ND) licence, and they are hosted by MDPI on mdpi.com as a courtesy and upon agreement with PAGEPress.
first_page
settings
Order Article Reprints
Font Type:
Arial Georgia Verdana
Font Size:
Aa Aa Aa
Line Spacing:
Column Width:
Background:
Case Report

Myeloid Sarcoma without Circulating Leukemia Mimicking Gastrointestinal Malignancy and Lymphoma

by
Sravanthi Ravulapati
,
Craig Siegel
,
Ameesh Dara
and
Jack M. Lionberger
*
Division of Hematology and Oncology, St. Louis University School of Medicine, 3rd Floor, 3655 Vista Avenue, St. Louis, MO 63110, USA
*
Author to whom correspondence should be addressed.
Hematol. Rep. 2018, 10(2), 7040; https://doi.org/10.4081/hr.2018.7040
Submission received: 10 November 2016 / Revised: 22 February 2017 / Accepted: 24 March 2017 / Published: 14 June 2018

Abstract

We present an unusual case of myeloid sarcoma with ascites and abdominal pain in which initial clinical, laboratory, and imaging studies suggested a gastrointestinal malignancy or lymphoma. Subsequent detection of leukemic ascites and blasts in a gastric, small bowel, and skin biopsy supported a diagnosis of myeloid sarcoma. Bone marrow biopsy revealed 15% blasts, and cytogenetics with an inversion 16 rearrangement was diagnostic of acute myeloid leukemia (AML). Positron emission tomography-computed tomography performed at presentation to stage a presumptive lymphoma found later utility in following the burden of extramedullary disease. Standard AML induction chemotherapy resulted in complete remission and was followed by three rounds of high dose cytarabine consolidation. The patient unfortunately relapsed leading to re-induction followed by allogeneic stem cell transplantation. This report describes the presentation, assessment, and management of myeloid sarcoma.
Keywords: myeloid sarcoma; granulocytic sarcoma; acute myeloid leukemia myeloid sarcoma; granulocytic sarcoma; acute myeloid leukemia

Share and Cite

MDPI and ACS Style

Ravulapati, S.; Siegel, C.; Dara, A.; Lionberger, J.M. Myeloid Sarcoma without Circulating Leukemia Mimicking Gastrointestinal Malignancy and Lymphoma. Hematol. Rep. 2018, 10, 7040. https://doi.org/10.4081/hr.2018.7040

AMA Style

Ravulapati S, Siegel C, Dara A, Lionberger JM. Myeloid Sarcoma without Circulating Leukemia Mimicking Gastrointestinal Malignancy and Lymphoma. Hematology Reports. 2018; 10(2):7040. https://doi.org/10.4081/hr.2018.7040

Chicago/Turabian Style

Ravulapati, Sravanthi, Craig Siegel, Ameesh Dara, and Jack M. Lionberger. 2018. "Myeloid Sarcoma without Circulating Leukemia Mimicking Gastrointestinal Malignancy and Lymphoma" Hematology Reports 10, no. 2: 7040. https://doi.org/10.4081/hr.2018.7040

APA Style

Ravulapati, S., Siegel, C., Dara, A., & Lionberger, J. M. (2018). Myeloid Sarcoma without Circulating Leukemia Mimicking Gastrointestinal Malignancy and Lymphoma. Hematology Reports, 10(2), 7040. https://doi.org/10.4081/hr.2018.7040

Article Metrics

Back to TopTop