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Pediatric Reports
Volume 6
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10.4081/pr.2014.5118
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Article

Health and Development of Children Born after Assisted Reproductive Technology and Sub-Fertility Compared to Naturally Conceived Children: Data from a National Study

by
Alastair G. Sutcliffe
1,
Edward Melhuish
1,
Jacqueline Barnes
2,4 and
Julian Gardiner
2,*
1
Institute of Child Health, University College London
2
Institute for the Study of Children, Families and Social Issues, Birkbeck, University of London
3
University of Oxford
4
Tavistock and Portman NHS Foundation Trust, London, UK
*
Author to whom correspondence should be addressed.
Pediatr. Rep. 2014, 6(1), 5118; https://doi.org/10.4081/pr.2014.5118
Submission received: 8 October 2013 / Revised: 8 October 2013 / Accepted: 27 November 2013 / Published: 28 February 2014

Abstract

In a non-matched case-control study using data from two large national cohort studies, we investigated whether indicators of child health and development up to 7 years of age differ between children conceived using assisted reproductive technology (ART), children born after sub-fertility (more than 24 months of trying for conception) and other children. Information on ART use/sub-fertility was available for 23,649 children. There were 227 cases (children conceived through ART) and two control groups: 783 children born to sub-fertile couples, and 22,639 children born to couples with no fertility issues. In models adjusted for social and demographic factors there were significant differences between groups in rate of hospital admissions before the children were 9 months old (P=0.029), with the ART group showing higher rates of hospital admission than the no fertility issues control group, the sub-fertile control group being intermediate between the two. Children born after ART had comparable health and development beyond 9 months of age to their naturally conceived peers. This applied to the whole sample and to a sub-sample of children from deprived neighborhoods.
Keywords: assisted reproductive technology; child health; sub-fertility assisted reproductive technology; child health; sub-fertility

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MDPI and ACS Style

Sutcliffe, A.G.; Melhuish, E.; Barnes, J.; Gardiner, J. Health and Development of Children Born after Assisted Reproductive Technology and Sub-Fertility Compared to Naturally Conceived Children: Data from a National Study. Pediatr. Rep. 2014, 6, 5118. https://doi.org/10.4081/pr.2014.5118

AMA Style

Sutcliffe AG, Melhuish E, Barnes J, Gardiner J. Health and Development of Children Born after Assisted Reproductive Technology and Sub-Fertility Compared to Naturally Conceived Children: Data from a National Study. Pediatric Reports. 2014; 6(1):5118. https://doi.org/10.4081/pr.2014.5118

Chicago/Turabian Style

Sutcliffe, Alastair G., Edward Melhuish, Jacqueline Barnes, and Julian Gardiner. 2014. "Health and Development of Children Born after Assisted Reproductive Technology and Sub-Fertility Compared to Naturally Conceived Children: Data from a National Study" Pediatric Reports 6, no. 1: 5118. https://doi.org/10.4081/pr.2014.5118

APA Style

Sutcliffe, A. G., Melhuish, E., Barnes, J., & Gardiner, J. (2014). Health and Development of Children Born after Assisted Reproductive Technology and Sub-Fertility Compared to Naturally Conceived Children: Data from a National Study. Pediatric Reports, 6(1), 5118. https://doi.org/10.4081/pr.2014.5118

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