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Pediatric Reports
Volume 11
Issue 4
10.4081/pr.2019.8248
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Article

Serological Profile of Hepatitis B in Children after the Introduction of Its Vaccination in Burkina Faso

by
Makoura Barro
1,*,
Diane Valea
2,
Saga Alain Ouermi
3,
Sanata Sessouma
2,
Bintou Sanogo
1,
Ibrahim Ad Bafa Ouattara
1,
Abdoul Salam Ouedraogo
4,
Boubacar Nacro
1 and
Georges Moyen
5
1
Department of Pediatrics, Sourô Sanou University Hospital, Bobo-Dioulasso
2
Virology Laboratory of Centre Muraz, IRSS/DRO, Bobo- Dioulasso
3
Department of Pediatrics, Régional Hospital of Ouahigouya
4
Laboratory Department, Sourô Sanou University Hospital, Bobo-Dioulasso
5
University of Brazzaville
*
Author to whom correspondence should be addressed.
Pediatr. Rep. 2019, 11(4), 8248; https://doi.org/10.4081/pr.2019.8248
Submission received: 17 July 2019 / Revised: 3 October 2019 / Accepted: 4 October 2019 / Published: 2 December 2019

Abstract

Viral hepatitis B is a public health issue. We establish the children serological profile of hepatitis B in Bobo-Dioulasso, six years after the introduction of hepatitis B vaccine into the Expanded Program on Immunization. This was a descriptive study of prospective data collection carried out in the Department of Pediatrics and the laboratory of virology of the Centre MURAZ of Bobo-Dioulasso between March 2013 and May 2013. Blood samples were made in search of the following hepatitis B serological markers: anti-HBcAb total, HBsAg, Ac anti-HBs, HBeAg, AcHBs, IgM anti-HBc total. The ELISA method with the Monolisa BIORAD reagents was used. A total of 2015 children were included, 1026 (50, 9%) boys and 989 (49.1%) girls, at an average age of 58±48 months. Out of these 2015 children, 53 (2.6%) were positive to HBsAg including 19 vaccinated cases, one child has received 3 doses plus 1 booster dose of hepatitis B vaccine. We found no statistically significant difference in the carriage of serologic markers of hepatitis B between the unvaccinated group and the vaccinated group. Large-scale studies should be carried out in Burkina Faso to see the real impact of vaccination on the health of our populations.
Keywords: Hepatitis B; prevalence; children; serological profile; Bobo-Dioulasso Hepatitis B; prevalence; children; serological profile; Bobo-Dioulasso

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MDPI and ACS Style

Barro, M.; Valea, D.; Ouermi, S.A.; Sessouma, S.; Sanogo, B.; Ouattara, I.A.B.; Ouedraogo, A.S.; Nacro, B.; Moyen, G. Serological Profile of Hepatitis B in Children after the Introduction of Its Vaccination in Burkina Faso. Pediatr. Rep. 2019, 11, 8248. https://doi.org/10.4081/pr.2019.8248

AMA Style

Barro M, Valea D, Ouermi SA, Sessouma S, Sanogo B, Ouattara IAB, Ouedraogo AS, Nacro B, Moyen G. Serological Profile of Hepatitis B in Children after the Introduction of Its Vaccination in Burkina Faso. Pediatric Reports. 2019; 11(4):8248. https://doi.org/10.4081/pr.2019.8248

Chicago/Turabian Style

Barro, Makoura, Diane Valea, Saga Alain Ouermi, Sanata Sessouma, Bintou Sanogo, Ibrahim Ad Bafa Ouattara, Abdoul Salam Ouedraogo, Boubacar Nacro, and Georges Moyen. 2019. "Serological Profile of Hepatitis B in Children after the Introduction of Its Vaccination in Burkina Faso" Pediatric Reports 11, no. 4: 8248. https://doi.org/10.4081/pr.2019.8248

APA Style

Barro, M., Valea, D., Ouermi, S. A., Sessouma, S., Sanogo, B., Ouattara, I. A. B., Ouedraogo, A. S., Nacro, B., & Moyen, G. (2019). Serological Profile of Hepatitis B in Children after the Introduction of Its Vaccination in Burkina Faso. Pediatric Reports, 11(4), 8248. https://doi.org/10.4081/pr.2019.8248

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