Next Article in Journal
Studying of Cultural Properties of Pyricularia oryzae Cav. Strains in the South of Russia
Previous Article in Journal
Acetyleugenol from Acacia nilotica (L.) Exhibits a Strong Antibacterial Activity and Its Phenyl and Indole Analogues Show a Promising Anti-TB Potential Targeting PknE/B Protein Kinases
 
 
Article

Spectral and Antibiotic Susceptibility of Pathogens Isolated from Saudi Patients with Diabetic Foot Infections

Biology Department, College of Science, Princess Norah Bent Abdul Rahman University, Riyadh 12271, Saudi Arabia
Microbiol. Res. 2021, 12(1), 16-20; https://doi.org/10.3390/microbiolres12010002
Received: 26 March 2020 / Accepted: 25 July 2020 / Published: 7 January 2021
Diabetic foot infections (DFIs) are a significant health issue and a common complication among patients with diabetes. To develop antibiotic therapy for these high-risk patients, the current study evaluates the scope of DFIs and identifies the causing microbes. It also measures spectrum and antibiotic susceptibility of the pathogens isolated from adults with DFIs in Saudi Arabia. To achieve the study objectives, a cross-sectional study was implemented and the baseline characteristics for 44 patients with DFIs were defined. Optimal aerobic and anaerobic microbiological techniques were utilized to culture specimens isolated from infected foot ulcers. The standard microbiological methods were employed to identify the bacterial isolates and antibiotic susceptibility testing was conducted following the procedures of the Clinical and Laboratory Standards Institute (CLSI). Results showed that 12 microorganisms were isolated from the participants’ diabetic foot ulcers. Staphylococcus Aureus was ranked first because it appeared in 29 (65.9%) cases. Streptococcus Agalactiae was ranked second and multi-microbial infections were also found. Most of the organisms were susceptible to Vancomycin, Ciprofloxacin, and Cefalexin, but they were resistant to Methicillin, Gentamicin, and Ampicillin antibiotics. Staphylococcus Aureus was most sensitive to Ciprofloxacin, while it was resistant to Methicillin. About 10% of the isolates were multidrug-resistant. The study concludes that while Vancomycin should be used empirically for Gram-positive isolates, Ciprofloxacin can be taken into consideration for most of the Gram-negatives aerobes. Based on including various microorganisms and the advent of multidrug-resistant strains, proper culture and sensitivity testing are necessary prior to the empirical therapy. View Full-Text
Keywords: diabetic foot infection; diabetic neuropathy; antimicrobial susceptibility; antibiotic resistance; multidrug-resistant organisms diabetic foot infection; diabetic neuropathy; antimicrobial susceptibility; antibiotic resistance; multidrug-resistant organisms
MDPI and ACS Style

Al-Mijalli, S.H.S. Spectral and Antibiotic Susceptibility of Pathogens Isolated from Saudi Patients with Diabetic Foot Infections. Microbiol. Res. 2021, 12, 16-20. https://doi.org/10.3390/microbiolres12010002

AMA Style

Al-Mijalli SHS. Spectral and Antibiotic Susceptibility of Pathogens Isolated from Saudi Patients with Diabetic Foot Infections. Microbiology Research. 2021; 12(1):16-20. https://doi.org/10.3390/microbiolres12010002

Chicago/Turabian Style

Al-Mijalli, Samiah Hamad S. 2021. "Spectral and Antibiotic Susceptibility of Pathogens Isolated from Saudi Patients with Diabetic Foot Infections" Microbiology Research 12, no. 1: 16-20. https://doi.org/10.3390/microbiolres12010002

Find Other Styles

Article Access Map by Country/Region

1
Back to TopTop