Khosta: A Genetic and Structural Point of View of the Forgotten Virus
Abstract
:1. Introduction
2. Materials and Methods
2.1. Phylogenetic Analyses
2.2. Structural and Molecular Dynamics Analyses
3. Results
4. Discussion
5. Conclusions
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Conflicts of Interest
References
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Khosta-1 | Khosta-2 | Wuhan | |
---|---|---|---|
Khosta-1 | - | 64 | 44 |
Khosta-2 | 79 | - | 46 |
Wuhan | 70 | 68 | - |
Khosta-1 a | Khosta-2 a | Wuhan b | |
---|---|---|---|
RBD | 0.08 ± 0.01 | 0.79 ± 0.01 | 2.13 |
NTD | 1.14 ± 0.05 | 4.89 ± 004 | 1.50 |
Method | Khosta-1 | Khosta-2 | Wuhan |
---|---|---|---|
FoldX 5.0 | −12.00 | −9.40 | −16.88 |
Mm/GBSA | −42.14 | −48.81 | −65.45 |
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Scarpa, F.; Imperia, E.; Ciccozzi, A.; Pascarella, S.; Quaranta, M.; Giovanetti, M.; Borsetti, A.; Petrosillo, N.; Ciccozzi, M. Khosta: A Genetic and Structural Point of View of the Forgotten Virus. Infect. Dis. Rep. 2023, 15, 307-318. https://doi.org/10.3390/idr15030031
Scarpa F, Imperia E, Ciccozzi A, Pascarella S, Quaranta M, Giovanetti M, Borsetti A, Petrosillo N, Ciccozzi M. Khosta: A Genetic and Structural Point of View of the Forgotten Virus. Infectious Disease Reports. 2023; 15(3):307-318. https://doi.org/10.3390/idr15030031
Chicago/Turabian StyleScarpa, Fabio, Elena Imperia, Alessandra Ciccozzi, Stefano Pascarella, Miriana Quaranta, Marta Giovanetti, Alessandra Borsetti, Nicola Petrosillo, and Massimo Ciccozzi. 2023. "Khosta: A Genetic and Structural Point of View of the Forgotten Virus" Infectious Disease Reports 15, no. 3: 307-318. https://doi.org/10.3390/idr15030031