Next Article in Journal
Reevaluation of an Established In Vivo Gastric Vessel Bleed Model for Hemostatic Device Safety and Efficacy Testing
Next Article in Special Issue
MicroRNA 133A Regulates Squalene Epoxidase Expression in Colorectal Cancer Cells to Control Cell Proliferation and Cholesterol Production
Previous Article in Journal
Smoking and Risk of Fatty Liver Disease: A Meta-Analysis of Cohort Studies
 
 
Article
Peer-Review Record

Screening Colonoscopy Uptake Among Adult Stroke Survivors: Findings from the 2022 BRFSS Data

Gastroenterol. Insights 2025, 16(1), 2; https://doi.org/10.3390/gastroent16010002
by Benjamin E. Ansa 1,*, Alaina Head 2, Zola Johnson 2, Wonder King Selassie Hatekah 3, Beulah Ansa 3 and Darryl Nettles 4
Reviewer 1: Anonymous
Reviewer 2: Anonymous
Reviewer 3: Anonymous
Gastroenterol. Insights 2025, 16(1), 2; https://doi.org/10.3390/gastroent16010002
Submission received: 15 November 2024 / Revised: 19 December 2024 / Accepted: 1 January 2025 / Published: 6 January 2025
(This article belongs to the Special Issue Novelties in Colorectal Surgery and Proctology)

Round 1

Reviewer 1 Report

Comments and Suggestions for Authors

please see the attached document

Comments for author File: Comments.pdf

Author Response

Comments:

Comments on screening colonoscopy uptake 
This manuscript pointed out that difference in race and socioeconomic state will 
make the rate of screening colonoscopy different. It is an important issue for 
establishment of policy for health promotion since if the screening scope could be 
broadened, detection rate of colorectal cancer might be different. 
The article might be accepted for publication in this edition. However, as the 
detection rate of colorectal cancer showed no statistically significant difference 
between patient with and without past history of stroke, these findings made screening 
colonoscopy appearing to be not valuable enough. It would be better if the authors could 
provide more information about what percentage of stroke is really cryptogenic? Cancer 
and stroke shared similar risk factors, only in cases of stroke without obvious evil 
habits and metabolic aberration, detection of colorectal cancer in these patients could 
be probably attributed to correlating with cancer itself.

Response:

The authors thank the reviewer for the time and effort spent in participating in the review process of our manuscript. The comments have helped to improve the quality of the paper. We have tried to address your comment below.

The information about the percentage of cryptogenic stroke is already provided in line 56 of the manuscript: "Almost one-third of stroke patients aged 18 to 49 years have cryptogenic stroke". We also added a sentence and an additional reference in line 56: "Cryptogenic stroke accounts for 30% to 40% of ischemic stroke" (see highlighted text in yellow).

Thanks again.

Author Response File: Author Response.pdf

Reviewer 2 Report

Comments and Suggestions for Authors

It is difficult to find the relationship between colonoscopy and stroke. Probably a deeper analysis could find the answer for this question. 

Author Response

Comments:

It is difficult to find the relationship between colonoscopy and stroke. Probably a deeper analysis could find the answer for this question. 

Response:

The authors thank the reviewer for the time and effort spent in participating in the review process of our manuscript. We have tried to address your comment below.

In our manuscript we attempted to present the relationship between colonoscopy and stroke. Our analysis revealed that stroke survivors were 1.309 times (Confidence interval (C.I.) = 1.307, 1.311; p<0.001) more likely to report having a screening colonoscopy compared to those without stroke (See lines 156-158).

Thank you again.

Author Response File: Author Response.pdf

Reviewer 3 Report

Comments and Suggestions for Authors

In the Introduction section, the authors describe the importance of the subject chosen and clearly state the link between stroke and colo-rectal cancer. Therefore, it increases the interest of the reader regarding the article.

The Materials and Methods section presents the design of the study, taking into consideration the ethical aspects of the study.

The results are presented in detail, using tables and figures for better understanding of them by the reader. Statistical data is also provided in this section.

After comparing the results with other studies from literature and presenting the study limitations, the conclusions are stated based on the results obtained.

Author Response

Comments

In the Introduction section, the authors describe the importance of the subject chosen and clearly state the link between stroke and colorectal cancer. Therefore, it increases the interest of the reader regarding the article.

The Materials and Methods section presents the design of the study, taking into consideration the ethical aspects of the study.

The results are presented in detail, using tables and figures for better understanding of them by the reader. Statistical data is also provided in this section.

After comparing the results with other studies from literature and presenting the study limitations, the conclusions are stated based on the results obtained.

Response:

The authors thank the reviewer for the time and effort spent in participating in the review process of our manuscript. The section-by-section evaluation of the manuscript by the reviewer is highly appreciated. The comments have helped to improve the quality of the paper. 

Author Response File: Author Response.pdf

Back to TopTop