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Case Report

Neuro-Ophthalmological Manifestations after Intramuscular Medroxyprogesterone: A forme fruste of Idiopathic Intracranial Hypertension?

1
Department of General Medicine, San Fernando General Hospital, Trinidad and Tobago
2
Department of Clinical Medical Sciences, University of the West Indies, St. Augustine, Trinidad and Tobago
3
Neurology Unit, San Fernando Teaching Hospital, University of West Indies, San Fernando, Trinidad and Tobago
*
Author to whom correspondence should be addressed.
Neurol. Int. 2016, 8(3), 6132; https://doi.org/10.4081/ni.2016.6132
Submission received: 2 August 2015 / Revised: 25 January 2016 / Accepted: 8 August 2016 / Published: 30 September 2016

Abstract

We report a case of a 22-year-old female student nurse who presented to hospital with an acute neuro-ophthalmological syndrome characterized by papilledema, ataxia, ophthalmoplegia and headache after a single first time use of 150 mg medroxyprogesterone intramuscular injection. Clinical, laboratory, radiological and ophthalmological investigations were in keeping with the diagnosis of idiopathic intracranial hypertension but lumbar puncture did not show a raised cerebrospinal fluid pressure suggesting a forme fruste of this entity. Her neuro-ophthalmological clinical features responded well to acetazolamide and diagnostic/ therapeutic lumbar puncture. Full recovery was achieved three months after medroxyprogesterone usage. Health care providers must be aware of this adverse drug reaction.
Keywords: Ataxia; papilledema; medroxyprogesterone; modified Dandy criteria; forme fruste Ataxia; papilledema; medroxyprogesterone; modified Dandy criteria; forme fruste

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MDPI and ACS Style

Bahall, M.; Reyes, A.J.; Ramcharan, K.; Hosein, N.; Seegobin, K.; Bahall, K.; Sharma, H.; Dhansingh, S.; Mahabir, A. Neuro-Ophthalmological Manifestations after Intramuscular Medroxyprogesterone: A forme fruste of Idiopathic Intracranial Hypertension? Neurol. Int. 2016, 8, 6132. https://doi.org/10.4081/ni.2016.6132

AMA Style

Bahall M, Reyes AJ, Ramcharan K, Hosein N, Seegobin K, Bahall K, Sharma H, Dhansingh S, Mahabir A. Neuro-Ophthalmological Manifestations after Intramuscular Medroxyprogesterone: A forme fruste of Idiopathic Intracranial Hypertension? Neurology International. 2016; 8(3):6132. https://doi.org/10.4081/ni.2016.6132

Chicago/Turabian Style

Bahall, Mandreker, Antonio Jose Reyes, Kanterpersad Ramcharan, Nadeem Hosein, Karan Seegobin, Krishni Bahall, Hiranyadeva Sharma, Stephanie Dhansingh, and Amanda Mahabir. 2016. "Neuro-Ophthalmological Manifestations after Intramuscular Medroxyprogesterone: A forme fruste of Idiopathic Intracranial Hypertension?" Neurology International 8, no. 3: 6132. https://doi.org/10.4081/ni.2016.6132

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