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Neurology International
Volume 3
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10.4081/ni.2011.e11
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Neurology International is published by MDPI from Volume 12 Issue 3 (2020). Previous articles were published by another publisher in Open Access under a CC-BY licence, and they are hosted by MDPI on mdpi.com as a courtesy and upon agreement with PAGEPress.
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Case Report

Benign Fasciculations and Corticosteroid Use: Possible Association? An Update

by
Marco Orsini
1,2,*,
Flavio R. Sztajnbok
3,
Acary Bulle Oliveira
4,
Marco Antonio Araújo Leite
1,
Peter Salem Júnior
1,
Marcos R.G. de Freitas
1,
Osvaldo J.M. Nascimento
1,
Júlio Guilherme Silva
1,2,
Marzia Puccioni Sholer
5,
Fernando Silva Guimarães
2,
Alessandra Cardoso Pereira
3,
Sara Lúcia Silveira de Menezes
2,
Antonio Marcos da Silva Catharino
1 and
Fabrício Bino
3
1
Neurology Service – Antonio Pedro University Hospital – Federal Fluminense University – HUAP – UFF, Herotides de Oliveira, 2(801), Jardim Icaraí, Niterói, RJ, Brazil
2
Sciences Rehabilitation Masters Program – UNISUAM, Brazil
3
Medicine Department – Grande Rio University, Rio de Janeiro, Brazil
4
Neurology Department – São Paulo Federal University – UNIFESP, São Paulo, Brazil
5
Cerebrospinal Fluid Laboratory and Clinical Pathology Service at the Clementino Fraga Filho Hospital of the Federal University of Rio de Janeiro (HUCFF/UFRJ), Brazil
*
Author to whom correspondence should be addressed.
Neurol. Int. 2011, 3(2), e11; https://doi.org/10.4081/ni.2011.e11
Submission received: 26 May 2011 / Revised: 27 May 2011 / Accepted: 30 August 2011 / Published: 20 September 2011

Abstract

Fasciculations are characterized by visible subtle and fast contractions of muscle, even wormlike in movement, by the contraction of a fascicle of muscle fibers. The authors present the case study of a 28-year-old patient with the appearance of migratory and diffuse fasciculations with an onset after partial tapering off of oral corticosteroides (60 mg total dose) indicated for treatment of Minimal change Glomerulopathy. Clinical Neurological physical exam allied with an ENMG, besides other complementary laboratory exams were used for screening the above-mentioned patient. Afterwards, current research relating to the topic at hand was made in order to update the data available in the Bireme, Scielo and PubMed Data Banks using the following key words: Fasciculation’s, motor neuron disease, and benign fasciculations in the Portuguese, English as well as Spanish language. Although fasciculation’s are most commonly associated with Motor neuron disease as well as with certain metabolic disorders, they may also be present in individuals with absolutely no underlying pathological disorders. In our case, fasciculation potentials that have been present for six months, with no other signs of a neurogenic disorder as well as absence of laboratory findings, the patient received a diagnosis of Benign Fasciculation Syndrome (BFS).We believe that the use of corticosteroides in high doses with subsequent tapering contributed to the fasciculation’s, especially due to the changes that this causes on the ionic channels. Fasciculation’s are symptoms seen in a large range of conditions, and also being the main symptom of the so-called Benign Fasciculation Syndrome. We have presented an example of this clinical syndrome in a patient whose complaint was fasciculation’s, with complete clinical remission of symptoms following complete tapering off of corticosteroid six months previously.
Keywords: eletroneuromyography; fasciculation’s; benign fasciculation syndrome eletroneuromyography; fasciculation’s; benign fasciculation syndrome

Share and Cite

MDPI and ACS Style

Orsini, M.; Sztajnbok, F.R.; Oliveira, A.B.; Araújo Leite, M.A.; Salem Júnior, P.; de Freitas, M.R.G.; Nascimento, O.J.M.; Silva, J.G.; Puccioni Sholer, M.; Silva Guimarães, F.; et al. Benign Fasciculations and Corticosteroid Use: Possible Association? An Update. Neurol. Int. 2011, 3, e11. https://doi.org/10.4081/ni.2011.e11

AMA Style

Orsini M, Sztajnbok FR, Oliveira AB, Araújo Leite MA, Salem Júnior P, de Freitas MRG, Nascimento OJM, Silva JG, Puccioni Sholer M, Silva Guimarães F, et al. Benign Fasciculations and Corticosteroid Use: Possible Association? An Update. Neurology International. 2011; 3(2):e11. https://doi.org/10.4081/ni.2011.e11

Chicago/Turabian Style

Orsini, Marco, Flavio R. Sztajnbok, Acary Bulle Oliveira, Marco Antonio Araújo Leite, Peter Salem Júnior, Marcos R.G. de Freitas, Osvaldo J.M. Nascimento, Júlio Guilherme Silva, Marzia Puccioni Sholer, Fernando Silva Guimarães, and et al. 2011. "Benign Fasciculations and Corticosteroid Use: Possible Association? An Update" Neurology International 3, no. 2: e11. https://doi.org/10.4081/ni.2011.e11

APA Style

Orsini, M., Sztajnbok, F. R., Oliveira, A. B., Araújo Leite, M. A., Salem Júnior, P., de Freitas, M. R. G., Nascimento, O. J. M., Silva, J. G., Puccioni Sholer, M., Silva Guimarães, F., Cardoso Pereira, A., Silveira de Menezes, S. L., da Silva Catharino, A. M., & Bino, F. (2011). Benign Fasciculations and Corticosteroid Use: Possible Association? An Update. Neurology International, 3(2), e11. https://doi.org/10.4081/ni.2011.e11

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