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Case Report

Use of Non-Invasive Ventilation to Facilitate Extubation in a Patient with Amyotrophic Lateral Sclerosis with Hypercapnic Respiratory Failure

1
Department of Medicine, University of Maryland School of Medicine, Baltimore, MD, USA
2
Department of Neurology, University of Maryland School of Medicine, Baltimore, MD, USA
3
Department of Rehabilitation Services, University of Maryland Medical Center Midtown Campus, Baltimore, MD, USA
4
VA Maryland Health Care System, Baltimore, MD, USA
5
Department of Neurology, Temple University School of Medicine, Philadelphia, PA, USA
*
Author to whom correspondence should be addressed.
Neurol. Int. 2019, 11(2), 8102; https://doi.org/10.4081/ni.2019.8102
Submission received: 6 March 2019 / Revised: 6 March 2019 / Accepted: 27 May 2019 / Published: 18 June 2019

Abstract

We present the case of a 44-year-old man with amyotrophic lateral sclerosis (ALS) intubated for hypercapnic respiratory failure and aspiration pneumonia. The patient was successfully extubated, transitioned to non-invasive ventilation and lived at home comfortably for 17 months, with good functional status for the first year. This case highlights the potential of prolonged survival post extubation in patients with advanced ALS and respiratory failure. The patient was managed post-discharge in a multidisciplinary ALS clinic by experienced neuromuscular and pulmonary specialists.
Keywords: amyotrophic lateral sclerosis; non-invasive ventilation; acute respiratory failure; invasive mechanical ventilation; extubation amyotrophic lateral sclerosis; non-invasive ventilation; acute respiratory failure; invasive mechanical ventilation; extubation

Share and Cite

MDPI and ACS Style

Diaz-Abad, M.; Chauhan, C.; Epps, D.; Russell, J.W.; Kwan, J. Use of Non-Invasive Ventilation to Facilitate Extubation in a Patient with Amyotrophic Lateral Sclerosis with Hypercapnic Respiratory Failure. Neurol. Int. 2019, 11, 8102. https://doi.org/10.4081/ni.2019.8102

AMA Style

Diaz-Abad M, Chauhan C, Epps D, Russell JW, Kwan J. Use of Non-Invasive Ventilation to Facilitate Extubation in a Patient with Amyotrophic Lateral Sclerosis with Hypercapnic Respiratory Failure. Neurology International. 2019; 11(2):8102. https://doi.org/10.4081/ni.2019.8102

Chicago/Turabian Style

Diaz-Abad, Montserrat, Chandana Chauhan, Denise Epps, James W. Russell, and Justin Kwan. 2019. "Use of Non-Invasive Ventilation to Facilitate Extubation in a Patient with Amyotrophic Lateral Sclerosis with Hypercapnic Respiratory Failure" Neurology International 11, no. 2: 8102. https://doi.org/10.4081/ni.2019.8102

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