Next Article in Journal
Stroke in Neurological Services in Italy
Previous Article in Journal
Cognitive Effects of Lamotrigine Versus Topiramate as Adjunctive Therapy in Older Adults with Epilepsy
 
 
Search for Articles:
Title / Keyword
Author / Affiliation / Email
Journal
Article Type
 
 
Advanced Search
 
Section
Special Issue
Volume
Issue
Number
Page
 
Journals
Neurology International
Volume 1
Issue 1
10.4081/ni.2009.e7
neurolint-logo
Submit to this Journal Review for this Journal Propose a Special Issue
► Article Menu

Article Menu

share Share announcement Help format_quote Cite question_answer Discuss in SciProfiles
Neurology International is published by MDPI from Volume 12 Issue 3 (2020). Previous articles were published by another publisher in Open Access under a CC-BY licence, and they are hosted by MDPI on mdpi.com as a courtesy and upon agreement with PAGEPress.
first_page
settings
Order Article Reprints
Font Type:
Arial Georgia Verdana
Font Size:
Aa Aa Aa
Line Spacing:
Column Width:
Background:
Article

Amyloid Myopathy: A Diagnostic Challenge

by
Heli Tuomaala
1,2,
Mikko Kärppä
1,
Hannu Tuominen
3 and
Anne M. Remes
1,2,*
1
Department of Neurology, University of Oulu, Oulu, Finland
2
Clinical Research Center, Oulu University Hospital, Finland
3
Department of Pathology, University of Oulu, Oulu, Finland
*
Author to whom correspondence should be addressed.
Neurol. Int. 2009, 1(1), e7; https://doi.org/10.4081/ni.2009.e7
Submission received: 26 February 2009 / Revised: 8 June 2009 / Accepted: 11 June 2009 / Published: 3 August 2009

Abstract

Amyloid myopathy (AM) is a rare manifestation of primary systemic amyloidosis (AL). Like inflammatory myopathies, it presents with proximal muscle weakness and an increased creatine kinase level. We describe a case of AL with severe, rapidly progressive myopathy as the initial symptom. The clinical manifestation and muscle biopsy were suggestive of inclusion body myositis. AM was not suspected until amyloidosis was seen in the gastric mucosal biopsy. The muscle biopsy was then re-examined more specifically, and Congo red staining eventually showed vascular and interstitial amyloid accumulation, which led to a diagnosis of AM. The present case illustrates the fact that the clinical picture of AM can mimic that of inclusion body myositis.
Keywords: amyloid myopathy; amyloidosis; congo red; magnetic resonance imaging; myopathy amyloid myopathy; amyloidosis; congo red; magnetic resonance imaging; myopathy

Share and Cite

MDPI and ACS Style

Tuomaala, H.; Kärppä, M.; Tuominen, H.; Remes, A.M. Amyloid Myopathy: A Diagnostic Challenge. Neurol. Int. 2009, 1, e7. https://doi.org/10.4081/ni.2009.e7

AMA Style

Tuomaala H, Kärppä M, Tuominen H, Remes AM. Amyloid Myopathy: A Diagnostic Challenge. Neurology International. 2009; 1(1):e7. https://doi.org/10.4081/ni.2009.e7

Chicago/Turabian Style

Tuomaala, Heli, Mikko Kärppä, Hannu Tuominen, and Anne M. Remes. 2009. "Amyloid Myopathy: A Diagnostic Challenge" Neurology International 1, no. 1: e7. https://doi.org/10.4081/ni.2009.e7

APA Style

Tuomaala, H., Kärppä, M., Tuominen, H., & Remes, A. M. (2009). Amyloid Myopathy: A Diagnostic Challenge. Neurology International, 1(1), e7. https://doi.org/10.4081/ni.2009.e7

Article Metrics

Back to TopTop