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Review

A Comprehensive Review of Patented Technologies to Fabricate Orodispersible Films: Proof of Patent Analysis (2000–2020)

1
Department of Pharmaceutics, JSS College of Pharmacy, JSS Academy of Higher Education and Research (JSSAHER), Sri Shivarathreeshwara Nagar, Mysore 570015, India
2
Pharmaceutical Sciences Laboratory, Faculty of Science and Engineering, ÅboAkademi University, 20520 Turku, Finland
*
Author to whom correspondence should be addressed.
Academic Editors: Belén Begines and Ana Alcudia
Pharmaceutics 2022, 14(4), 820; https://doi.org/10.3390/pharmaceutics14040820
Received: 2 March 2022 / Revised: 22 March 2022 / Accepted: 5 April 2022 / Published: 8 April 2022
Orodispersible films (ODFs)are ultra-thin, stamp-sized, rapidly disintegrating, and attractive oral drug delivery dosage forms best suited for the pediatric and geriatric patient populations. They can be fabricated by different techniques, but the most popular, simple, and industrially applicable technique is the solvent casting method (SCM). In addition, they can also be fabricated by extrusion, printing, electrospinning, and by a combination of these technologies (e.g., SCM + printing). The present review is aimed to provide a comprehensive overview of patented technologies of the last two decades to fabricate ODFs. Through this review, we present evidence to adamantly confirm that SCM is the most popular method while electrospinning is the most recent and upcoming method to fabricate ODFs. We also speculate around the more patent-protected technologies especially in the domain of printing (two or three-dimensional), extrusion (ram or hot-melt extrusion), and electrospinning, or a combination of the methods thereof. View Full-Text
Keywords: orodispersible films; solvent casting; printing technologies; electrospinning orodispersible films; solvent casting; printing technologies; electrospinning
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MDPI and ACS Style

Gupta, M.S.; Gowda, D.V.; Kumar, T.P.; Rosenholm, J.M. A Comprehensive Review of Patented Technologies to Fabricate Orodispersible Films: Proof of Patent Analysis (2000–2020). Pharmaceutics 2022, 14, 820. https://doi.org/10.3390/pharmaceutics14040820

AMA Style

Gupta MS, Gowda DV, Kumar TP, Rosenholm JM. A Comprehensive Review of Patented Technologies to Fabricate Orodispersible Films: Proof of Patent Analysis (2000–2020). Pharmaceutics. 2022; 14(4):820. https://doi.org/10.3390/pharmaceutics14040820

Chicago/Turabian Style

Gupta, Maram Suresh, Devegowda Vishakante Gowda, Tegginamath Pramod Kumar, and Jessica M. Rosenholm. 2022. "A Comprehensive Review of Patented Technologies to Fabricate Orodispersible Films: Proof of Patent Analysis (2000–2020)" Pharmaceutics 14, no. 4: 820. https://doi.org/10.3390/pharmaceutics14040820

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