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Emerging Treatment Strategies for Diabetes Mellitus and Associated Complications: An Update

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School of Pharmaceutical Sciences, Lovely Professional University, Phagwara 144411, Punjab, India
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Faculty of Pharmaceutical Sciences, PCTE Group of Institutes, Ludhiana 142021, Punjab, India
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SVKM’s NMIMS School of Pharmacy & Technology Management, Shirpur 425405, Maharashtra, India
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Department of Medical Biotechnology, College of Applied Medical Sciences, Qassim University, Buraydah 51452, Saudi Arabia
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Department of Medical Laboratories, College of Applied Medical Sciences, Qassim University, Buraydah 51452, Saudi Arabia
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Biology Department, College of Education, Majmaah University, Majmaah 11932, Saudi Arabia
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School of Pharmacy and Pharmaceutical Sciences, Ulster University, Coleraine BT52 1SA, UK
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Authors to whom correspondence should be addressed.
Academic Editor: Tao L. Lowe
Pharmaceutics 2021, 13(10), 1568; https://doi.org/10.3390/pharmaceutics13101568
Received: 20 July 2021 / Revised: 10 September 2021 / Accepted: 13 September 2021 / Published: 27 September 2021
(This article belongs to the Special Issue Applied Nanotechnology in Chronic Human Disease Management)
The occurrence of diabetes mellitus (DM) is increasing rapidly at an accelerating rate worldwide. The status of diabetes has changed over the last three generations; whereas before it was deemed a minor disease of older people but currently it is now one of the leading causes of morbidity and mortality among middle-aged and young people. High blood glucose-mediated functional loss, insulin sensitivity, and insulin deficiency lead to chronic disorders such as Type 1 and Type 2 DM. Traditional treatments of DM, such as insulin sensitization and insulin secretion cause undesirable side effects, leading to patient incompliance and lack of treatment. Nanotechnology in diabetes studies has encouraged the development of new modalities for measuring glucose and supplying insulin that hold the potential to improve the quality of life of diabetics. Other therapies, such as β-cells regeneration and gene therapy, in addition to insulin and oral hypoglycemic drugs, are currently used to control diabetes. The present review highlights the nanocarrier-based drug delivery systems and emerging treatment strategies of DM. View Full-Text
Keywords: diabetes mellitus; blood glucose level; insulin; treatment strategies; nanocarrier diabetes mellitus; blood glucose level; insulin; treatment strategies; nanocarrier
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MDPI and ACS Style

Mishra, V.; Nayak, P.; Sharma, M.; Albutti, A.; Alwashmi, A.S.S.; Aljasir, M.A.; Alsowayeh, N.; Tambuwala, M.M. Emerging Treatment Strategies for Diabetes Mellitus and Associated Complications: An Update. Pharmaceutics 2021, 13, 1568. https://doi.org/10.3390/pharmaceutics13101568

AMA Style

Mishra V, Nayak P, Sharma M, Albutti A, Alwashmi ASS, Aljasir MA, Alsowayeh N, Tambuwala MM. Emerging Treatment Strategies for Diabetes Mellitus and Associated Complications: An Update. Pharmaceutics. 2021; 13(10):1568. https://doi.org/10.3390/pharmaceutics13101568

Chicago/Turabian Style

Mishra, Vijay, Pallavi Nayak, Mayank Sharma, Aqel Albutti, Ameen S.S. Alwashmi, Mohammad A. Aljasir, Noorah Alsowayeh, and Murtaza M. Tambuwala 2021. "Emerging Treatment Strategies for Diabetes Mellitus and Associated Complications: An Update" Pharmaceutics 13, no. 10: 1568. https://doi.org/10.3390/pharmaceutics13101568

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