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Viruses 2017, 9(8), 223;

Influenza Virus Infection, Interferon Response, Viral Counter-Response, and Apoptosis

Institut Pasteur Korea, Gyeonggi-do 13488, Korea
Institute of Technology, University of Tartu, Tartu 50090, Estonia
Department of Clinical and Molecular Medicine, Norwegian University of Science and Technology, Trondheim 7028, Norway
Author to whom correspondence should be addressed.
Academic Editor: Marc Kvansakul
Received: 30 June 2017 / Revised: 27 July 2017 / Accepted: 8 August 2017 / Published: 12 August 2017
(This article belongs to the Special Issue Viral Infection and Apoptosis)
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Human influenza A viruses (IAVs) cause global pandemics and epidemics, which remain serious threats to public health because of the shortage of effective means of control. To combat the surge of viral outbreaks, new treatments are urgently needed. Developing new virus control modalities requires better understanding of virus-host interactions. Here, we describe how IAV infection triggers cellular apoptosis and how this process can be exploited towards the development of new therapeutics, which might be more effective than the currently available anti-influenza drugs. View Full-Text
Keywords: influenza virus; apoptosis; antiviral agent; innate immunity; host response influenza virus; apoptosis; antiviral agent; innate immunity; host response

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This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited (CC BY 4.0).

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Shim, J.M.; Kim, J.; Tenson, T.; Min, J.-Y.; Kainov, D.E. Influenza Virus Infection, Interferon Response, Viral Counter-Response, and Apoptosis. Viruses 2017, 9, 223.

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