The Adenovirus Genome Contributes to the Structural Stability of the Virion
Abstract
:1. Introduction
2. Adenovirus Biology
2.1. The Ad Genome
2.2. The Ad Virion
2.3. Packaging of Ad DNA into the Capsid
2.4. Adenovirus Infection
3. The Ad Genome Size and Virion Stability
3.1. Early Region 1-Deleted Ad Vectors
3.2. Helper-Dependent Ad Vectors
3.3. Virion Instability of Ad Vectors
4. Studies of Genome Size and Virion Stability in Other Viruses
5. Implications for Vector Design
6. Conclusions
Acknowledgments
Author Contributions
Conflicts of Interest
References and Notes
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Saha, B.; Wong, C.M.; Parks, R.J. The Adenovirus Genome Contributes to the Structural Stability of the Virion. Viruses 2014, 6, 3563-3583. https://doi.org/10.3390/v6093563
Saha B, Wong CM, Parks RJ. The Adenovirus Genome Contributes to the Structural Stability of the Virion. Viruses. 2014; 6(9):3563-3583. https://doi.org/10.3390/v6093563
Chicago/Turabian StyleSaha, Bratati, Carmen M. Wong, and Robin J. Parks. 2014. "The Adenovirus Genome Contributes to the Structural Stability of the Virion" Viruses 6, no. 9: 3563-3583. https://doi.org/10.3390/v6093563