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Communication

Characterization of a Novel SARS-CoV-2 Genetic Variant with Distinct Spike Protein Mutations

1
Saint Petersburg Pasteur Institute, 197101 Saint Petersburg, Russia
2
Martsinovsky Institute of Medical Parasitology, Tropical and Vector Borne Diseases, Sechenov First Moscow State Medical University, 119991 Moscow, Russia
3
Federal Service for Surveillance on Consumer Rights Protection and Human Well-Being, 127994 Moscow, Russia
*
Author to whom correspondence should be addressed.
Academic Editor: Larisa Rudenko
Viruses 2021, 13(6), 1029; https://doi.org/10.3390/v13061029
Received: 11 May 2021 / Revised: 27 May 2021 / Accepted: 27 May 2021 / Published: 29 May 2021
(This article belongs to the Special Issue State-of-the-Art Respiratory Viruses Research in Russia)
The COVID-19 pandemic, which began in Wuhan (Hubei, China), has been ongoing for about a year and a half. An unprecedented number of people around the world have been infected with SARS-CoV-2, the etiological agent of COVID-19. Despite the fact that the mortality rate for COVID-19 is relatively low, the total number of deaths has currently already reached more than three million and continues to increase due to high incidence. Since the beginning of the pandemic, a large number of sequences have been obtained and many genetic variants have been identified. Some of them bear significant mutations that affect biological properties of the virus. These genetic variants, currently Variants of Concern (VoC), include the so-called United Kingdom variant (20I/501Y), the Brazilian variant (20J/501Y.V3), and the South African variant (20H/501Y.V2). We describe here a novel SARS-CoV-2 variant with distinct spike protein mutations, first obtained at the end of January 2021 in northwest Russia. Therefore, it is necessary to pay attention to the dynamics of its spread among patients with COVID-19, as well as to study in detail its biological properties. View Full-Text
Keywords: SARS-CoV-2; COVID-19; variants of concern; northwest (NW) variant; Russia SARS-CoV-2; COVID-19; variants of concern; northwest (NW) variant; Russia
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MDPI and ACS Style

Gladkikh, A.; Dolgova, A.; Dedkov, V.; Sbarzaglia, V.; Kanaeva, O.; Popova, A.; Totolian, A. Characterization of a Novel SARS-CoV-2 Genetic Variant with Distinct Spike Protein Mutations. Viruses 2021, 13, 1029. https://doi.org/10.3390/v13061029

AMA Style

Gladkikh A, Dolgova A, Dedkov V, Sbarzaglia V, Kanaeva O, Popova A, Totolian A. Characterization of a Novel SARS-CoV-2 Genetic Variant with Distinct Spike Protein Mutations. Viruses. 2021; 13(6):1029. https://doi.org/10.3390/v13061029

Chicago/Turabian Style

Gladkikh, Anna, Anna Dolgova, Vladimir Dedkov, Valeriya Sbarzaglia, Olga Kanaeva, Anna Popova, and Areg Totolian. 2021. "Characterization of a Novel SARS-CoV-2 Genetic Variant with Distinct Spike Protein Mutations" Viruses 13, no. 6: 1029. https://doi.org/10.3390/v13061029

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