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Open AccessReview

Autophagy and Noroviruses

by Kevin Furlong 1 and Seungmin Hwang 1,2,3,4,*
1
Committee on Microbiology, The University of Chicago, Chicago, IL 60637, USA
2
Committee on Immunology, The University of Chicago, Chicago, IL 60637, USA
3
Committee on Cancer Biology, The University of Chicago, Chicago, IL 60637, USA
4
Department of Pathology, The University of Chicago, Chicago, IL 60637, USA
*
Author to whom correspondence should be addressed.
Viruses 2019, 11(3), 244; https://doi.org/10.3390/v11030244
Received: 16 February 2019 / Revised: 6 March 2019 / Accepted: 9 March 2019 / Published: 12 March 2019
(This article belongs to the Special Issue Noroviruses)
Autophagy is an essential cellular process by which a cell degrades materials within its cytoplasm. Intracellular pathogens like viruses must deal with autophagy, either positively or negatively, for their own survival and replication. For some viruses, autophagy can even play proviral roles, helping their replication or dissemination. For other viruses, including noroviruses, the exact role of autophagy is more complex. This short review seeks to summarize the known interactions between autophagy, autophagy proteins and norovirus, and to address remaining questions relevant to these interactions. View Full-Text
Keywords: norovirus; positive-sense RNA virus; autophagy; LC3 conjugation; replication compartment; interferon-inducible GTPases norovirus; positive-sense RNA virus; autophagy; LC3 conjugation; replication compartment; interferon-inducible GTPases
MDPI and ACS Style

Furlong, K.; Hwang, S. Autophagy and Noroviruses. Viruses 2019, 11, 244.

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