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Materials 2015, 8(2), 684-699;

Enhanced Hydrophilicity and Biocompatibility of Dental Zirconia Ceramics by Oxygen Plasma Treatment

Department of Bio-Industrial Mechatronics Engineering, National Chung Hsing University, Taichung City 402, Taiwan
Institute of Oral Science, Chung Shan Medical University, Taichung City 402, Taiwan
Department of Dentistry, Chung Shan Medical University Hospital, Taichung City 402, Taiwan
Author to whom correspondence should be addressed.
Academic Editor: Ihtesham ur Rehman
Received: 17 January 2015 / Accepted: 12 February 2015 / Published: 16 February 2015
(This article belongs to the Special Issue Dental Materials)
Full-Text   |   PDF [3145 KB, uploaded 16 February 2015]   |  


Surface properties play a critical role in influencing cell responses to a biomaterial. The objectives of this study were (1) to characterize changes in surface properties of zirconia (ZrO2) ceramic after oxygen plasma treatment; and (2) to determine the effect of such changes on biological responses of human osteoblast-like cells (MG63). The results indicated that the surface morphology was not changed by oxygen plasma treatment. In contrast, oxygen plasma treatment to ZrO2 not only resulted in an increase in hydrophilicity, but also it retained surface hydrophilicity after 5-min treatment time. More importantly, surface properties of ZrO2 modified by oxygen plasma treatment were beneficial for cell growth, whereas the surface roughness of the materials did not have a significant efficacy. It is concluded that oxygen plasma treatment was certified to be effective in modifying the surface state of ZrO2 and has the potential in the creation and maintenance of hydrophilic surfaces and the enhancement of cell proliferation and differentiation. View Full-Text
Keywords: zirconia; all ceramic; oxygen plasma; hydrophilicity; biocompatibility zirconia; all ceramic; oxygen plasma; hydrophilicity; biocompatibility

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Wu, C.-C.; Wei, C.-K.; Ho, C.-C.; Ding, S.-J. Enhanced Hydrophilicity and Biocompatibility of Dental Zirconia Ceramics by Oxygen Plasma Treatment. Materials 2015, 8, 684-699.

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