Next Article in Journal
A Perspective on the Prowaste Concept: Efficient Utilization of Plastic Waste through Product Design and Process Innovation
Next Article in Special Issue
Synthesis of Water-Dispersed Ferrecene/Phenylboronic Acid-Modified Bifunctional Gold Nanoparticles and the Application in Biosensing
Previous Article in Journal
Liquid Crystalline Network Composites Reinforced by Silica Nanoparticles
Previous Article in Special Issue
Nanostructural Engineering of Nanoporous Anodic Alumina for Biosensing Applications
Open AccessReview

Nanomaterials-Based Sensing Strategies for Electrochemical Detection of MicroRNAs

College of Chemistry and Chemical Engineering, Anyang Normal University, Anyang 455000, China
*
Author to whom correspondence should be addressed.
Materials 2014, 7(7), 5366-5384; https://doi.org/10.3390/ma7075366
Received: 23 May 2014 / Revised: 10 June 2014 / Accepted: 14 July 2014 / Published: 23 July 2014
(This article belongs to the Special Issue Advanced Nanomaterials for Biosensors)
MicroRNAs (miRNAs) play important functions in post-transcriptional regulation of gene expression. They have been regarded as reliable molecular biomarkers for many diseases including cancer. However, the content of miRNAs in cells can be low down to a few molecules per cell. Thus, highly sensitive analytical methods for miRNAs detection are desired. Recently, electrochemical biosensors have held great promise as devices suitable for point-of-care diagnostics and multiplexed platforms for fast, simple and low-cost nucleic acid analysis. Signal amplification by nanomaterials is one of the most popular strategies for developing ultrasensitive assay methods. This review surveys the latest achievements in the use of nanomaterials to detect miRNAs with a focus on electrochemical techniques. View Full-Text
Keywords: nanomaterials; miRNAs; electrochemistry; biosensors nanomaterials; miRNAs; electrochemistry; biosensors
Show Figures

Figure 1

MDPI and ACS Style

Xia, N.; Zhang, L. Nanomaterials-Based Sensing Strategies for Electrochemical Detection of MicroRNAs. Materials 2014, 7, 5366-5384.

Show more citation formats Show less citations formats

Article Access Map by Country/Region

1
Only visits after 24 November 2015 are recorded.
Back to TopTop