Next Article in Journal
A Perspective on the Prowaste Concept: Efficient Utilization of Plastic Waste through Product Design and Process Innovation
Next Article in Special Issue
Synthesis of Water-Dispersed Ferrecene/Phenylboronic Acid-Modified Bifunctional Gold Nanoparticles and the Application in Biosensing
Previous Article in Journal
Liquid Crystalline Network Composites Reinforced by Silica Nanoparticles
Previous Article in Special Issue
Nanostructural Engineering of Nanoporous Anodic Alumina for Biosensing Applications
Article Menu

Export Article

Open AccessReview
Materials 2014, 7(7), 5366-5384;

Nanomaterials-Based Sensing Strategies for Electrochemical Detection of MicroRNAs

College of Chemistry and Chemical Engineering, Anyang Normal University, Anyang 455000, China
Author to whom correspondence should be addressed.
Received: 23 May 2014 / Revised: 10 June 2014 / Accepted: 14 July 2014 / Published: 23 July 2014
(This article belongs to the Special Issue Advanced Nanomaterials for Biosensors)
Full-Text   |   PDF [1613 KB, uploaded 23 July 2014]   |  


MicroRNAs (miRNAs) play important functions in post-transcriptional regulation of gene expression. They have been regarded as reliable molecular biomarkers for many diseases including cancer. However, the content of miRNAs in cells can be low down to a few molecules per cell. Thus, highly sensitive analytical methods for miRNAs detection are desired. Recently, electrochemical biosensors have held great promise as devices suitable for point-of-care diagnostics and multiplexed platforms for fast, simple and low-cost nucleic acid analysis. Signal amplification by nanomaterials is one of the most popular strategies for developing ultrasensitive assay methods. This review surveys the latest achievements in the use of nanomaterials to detect miRNAs with a focus on electrochemical techniques. View Full-Text
Keywords: nanomaterials; miRNAs; electrochemistry; biosensors nanomaterials; miRNAs; electrochemistry; biosensors

Figure 1

This is an open access article distributed under the Creative Commons Attribution License (CC BY 3.0).

Share & Cite This Article

MDPI and ACS Style

Xia, N.; Zhang, L. Nanomaterials-Based Sensing Strategies for Electrochemical Detection of MicroRNAs. Materials 2014, 7, 5366-5384.

Show more citation formats Show less citations formats

Related Articles

Article Metrics

Article Access Statistics



[Return to top]
Materials EISSN 1996-1944 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert
Back to Top