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Materials 2019, 12(1), 164; https://doi.org/10.3390/ma12010164

Augmentation of DMLS Biomimetic Dental Implants with Weight-Bearing Strut to Balance of Biologic and Mechanical Demands: From Bench to Animal

1
School of Dentistry, College of Medicine, National Taiwan University, Taipei 10051, Taiwan
2
Department of Materials Science and Engineering, National Chiao-Tung University, Hsinchu 30010, Taiwan
3
Biomedical Technology and Device Research Laboratories, Industrial Technology Research Institute, Hsinchu 31040, Taiwan
4
Department of Orthopedic Surgery, College of Medicine, National Taiwan University, Taipei 10002, Taiwan
*
Authors to whom correspondence should be addressed.
Received: 8 December 2018 / Revised: 24 December 2018 / Accepted: 27 December 2018 / Published: 7 January 2019
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Abstract

A mismatch of elastic modulus values could result in undesirable bone resorption around the dental implant. The objective of this study was to optimize direct metal laser sintering (DMLS)-manufactured Ti6Al4V dental implants’ design, minimize elastic mismatch, allow for maximal bone ingrowth, and improve long-term fixation of the implant. In this study, DMLS dental implants with different morphological characteristics were fabricated. Three-point bending, torsional, and stability tests were performed to compare the mechanical properties of different designs. Improvement of the weaker design was attempted by augmentation with a longitudinal 3D-printed strut. The osseointegrative properties were evaluated. The results showed that the increase in porosity decreased the mechanical properties, while augmentation with a longitudinal weight-bearing strut can improve mechanical strength. Maximal alkaline phosphatase gene expression of MG63 cells attained on 60% porosity Ti6Al4V discs. In vivo experiments showed good incorporation of bone into the porous scaffolds of the DMLS dental implant, resulting in a higher pull-out strength. In summary, we introduced a new design concept by augmenting the implant with a longitudinal weight-bearing strut to achieve the ideal combination of high strength and low elastic modulus; our results showed that there is a chance to reach the balance of both biologic and mechanical demands. View Full-Text
Keywords: direct metal laser sintering; biomimetic; porous titanium; Ti6Al4V; 3D-printing direct metal laser sintering; biomimetic; porous titanium; Ti6Al4V; 3D-printing
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This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited (CC BY 4.0).

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Chang, J. .-C.; Tsai, P.-I.; Kuo, M. .-P.; Sun, J.-S.; Chen, S.-Y.; Shen, H.-H. Augmentation of DMLS Biomimetic Dental Implants with Weight-Bearing Strut to Balance of Biologic and Mechanical Demands: From Bench to Animal. Materials 2019, 12, 164.

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