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Materials 2018, 11(9), 1636; https://doi.org/10.3390/ma11091636

A Novel Fluoride Containing Bioactive Glass Paste is Capable of Re-Mineralizing Early Caries Lesions

1
Operative Dentistry Department, Faculty of Dentistry, King Abdulaziz University, Jeddah 21589, Saudi Arabia
2
Conservative Dentistry Department, Faculty of Dentistry, Alexandria University, Alexandria 21614, Egypt
3
Department of Orthodontics, Faculty of Dentistry, King Abdulaziz University, Jeddah 21589, Saudi Arabia
4
Dental Department, Alexandria University, Alexandria 21614, Egypt
5
Primary Health care Centre, Sabt Alalayah Hospital, Ministry of Health, Bisha 67611, Saudi Arabia
6
Physical Sciences in Relation to Dentistry, Institute of Dentistry, Dental Physical Sciences Unit, Queen Mary University of London, London E1 2AD, UK
*
Author to whom correspondence should be addressed.
Received: 1 July 2018 / Revised: 11 August 2018 / Accepted: 23 August 2018 / Published: 6 September 2018
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Abstract

White-spot-lesions (WSL) are a common complication associated with orthodontic treatment. In the current study, the remineralization efficacy of a BiominF® paste was compared to the efficacy of a fluoride gel. Methods: Orthodontic brackets were bonded to 60 human premolars buccal surfaces, which were covered with varnish, except a small treatment area (3 mm2). All specimens were challenged by a demineralization solution for 4 days. Specimens were assigned into 4 groups: BiominF® paste, Fluoride (4-min application), fluoride (twenty four hours application), and the control (n = 15). After cross-sectioning, enamel slabs having a thickness of approximately 100–120 μm were obtained. A TMR (Transverse Micro Radiography) technique was used to observe the sub-surface enamel lesions’ depth and mineral density, and their response to the remineralization protocols. One way ANOVA was used to analyze the results (α = 0.05). The top and the cross-sectional surfaces were observed using SEM/EDS. Results: Specimens treated with BiominF® paste showed significant decrease in delta z values, however lesion depth showed no significant difference when compared to the other three groups (p < 0.05). SEM/EDS observation showed the formation of crystal like structures on top of enamel demineralized surfaces, when treated with BiominF® paste. In conclusion BiominF® paste can be considered an effective remineralizing agent for white spot Lesions. View Full-Text
Keywords: fluoride bioactive glass; biomin; caries; enamel fluoride bioactive glass; biomin; caries; enamel
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This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).
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Bakry, A.S.; Abbassy, M.A.; Alharkan, H.F.; Basuhail, S.; Al-Ghamdi, K.; Hill, R. A Novel Fluoride Containing Bioactive Glass Paste is Capable of Re-Mineralizing Early Caries Lesions. Materials 2018, 11, 1636.

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