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Open AccessArticle

A Novel Fluoride Containing Bioactive Glass Paste is Capable of Re-Mineralizing Early Caries Lesions

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Operative Dentistry Department, Faculty of Dentistry, King Abdulaziz University, Jeddah 21589, Saudi Arabia
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Conservative Dentistry Department, Faculty of Dentistry, Alexandria University, Alexandria 21614, Egypt
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Department of Orthodontics, Faculty of Dentistry, King Abdulaziz University, Jeddah 21589, Saudi Arabia
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Dental Department, Alexandria University, Alexandria 21614, Egypt
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Primary Health care Centre, Sabt Alalayah Hospital, Ministry of Health, Bisha 67611, Saudi Arabia
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Physical Sciences in Relation to Dentistry, Institute of Dentistry, Dental Physical Sciences Unit, Queen Mary University of London, London E1 2AD, UK
*
Author to whom correspondence should be addressed.
Materials 2018, 11(9), 1636; https://doi.org/10.3390/ma11091636
Received: 1 July 2018 / Revised: 11 August 2018 / Accepted: 23 August 2018 / Published: 6 September 2018
White-spot-lesions (WSL) are a common complication associated with orthodontic treatment. In the current study, the remineralization efficacy of a BiominF® paste was compared to the efficacy of a fluoride gel. Methods: Orthodontic brackets were bonded to 60 human premolars buccal surfaces, which were covered with varnish, except a small treatment area (3 mm2). All specimens were challenged by a demineralization solution for 4 days. Specimens were assigned into 4 groups: BiominF® paste, Fluoride (4-min application), fluoride (twenty four hours application), and the control (n = 15). After cross-sectioning, enamel slabs having a thickness of approximately 100–120 μm were obtained. A TMR (Transverse Micro Radiography) technique was used to observe the sub-surface enamel lesions’ depth and mineral density, and their response to the remineralization protocols. One way ANOVA was used to analyze the results (α = 0.05). The top and the cross-sectional surfaces were observed using SEM/EDS. Results: Specimens treated with BiominF® paste showed significant decrease in delta z values, however lesion depth showed no significant difference when compared to the other three groups (p < 0.05). SEM/EDS observation showed the formation of crystal like structures on top of enamel demineralized surfaces, when treated with BiominF® paste. In conclusion BiominF® paste can be considered an effective remineralizing agent for white spot Lesions. View Full-Text
Keywords: fluoride bioactive glass; biomin; caries; enamel fluoride bioactive glass; biomin; caries; enamel
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MDPI and ACS Style

Bakry, A.S.; Abbassy, M.A.; Alharkan, H.F.; Basuhail, S.; Al-Ghamdi, K.; Hill, R. A Novel Fluoride Containing Bioactive Glass Paste is Capable of Re-Mineralizing Early Caries Lesions. Materials 2018, 11, 1636.

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