Photoluminescent Eu3+-Doped Calcium Phosphate Bone Cement and Its Mechanical Properties
Otto Schott Institute of Materials Research (OSIM), Friedrich Schiller University Jena, Löbdergraben 32, 07743 Jena, Germany
Author to whom correspondence should be addressed.
These authors contributed equally to this work.
Materials 2018, 11(9), 1610; https://doi.org/10.3390/ma11091610
Received: 17 July 2018 / Revised: 16 August 2018 / Accepted: 3 September 2018 / Published: 4 September 2018
(This article belongs to the Special Issue Mineral Bone Cements: Current Status and Future Prospects)
Calcium phosphate cements (CPC) are well-established bone replacement materials that have been used in dentistry and orthopedics for more than 25 years. The monitoring of bone cements and the associated healing processes in the human body is difficult and so far has often been achieved using cytotoxic X-ray contrast agent additives. These additives have a negative effect on the mechanical properties and setting time of the bone cement. In this paper, we present a novel approach to prepare contrastive CPC by the incorporation of luminescent Eu3+-doped hydroxyapatite (Eu:HAp) nanoparticles. Eu-doped CPC (Eu:CPC) exhibited enhanced mechanical properties compared to pure CPC. Furthermore, the red photoluminescence of Eu:CPC may allow the observation of CPC-related healing processes without the use of harmful ionizing radiation.