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Review

Minimally Invasive Interventional Procedures for Metastatic Bone Disease: A Comprehensive Review

Diagnostic and Interventional Radiology Unit, IRCCS Istituto Ortopedico Rizzoli, Via Pupilli 1, 40136 Bologna, Italy
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Curr. Oncol. 2022, 29(6), 4155-4177; https://doi.org/10.3390/curroncol29060332
Received: 1 May 2022 / Revised: 3 June 2022 / Accepted: 6 June 2022 / Published: 7 June 2022
(This article belongs to the Special Issue Treatment of Bone Metastasis)
Metastases are the main type of malignancy involving bone, which is the third most frequent site of metastatic carcinoma, after lung and liver. Skeletal-related events such as intractable pain, spinal cord compression, and pathologic fractures pose a serious burden on patients’ quality of life. For this reason, mini-invasive treatments for the management of bone metastases were developed with the goal of pain relief and functional status improvement. These techniques include embolization, thermal ablation, electrochemotherapy, cementoplasty, and MRI-guided high-intensity focused ultrasound. In order to achieve durable pain palliation and disease control, mini-invasive procedures are combined with chemotherapy, radiation therapy, surgery, or analgesics. The purpose of this review is to summarize the recently published literature regarding interventional radiology procedures in the treatment of cancer patients with bone metastases, focusing on the efficacy, complications, local disease control and recurrence rate. View Full-Text
Keywords: bone metastases; imaging; interventional radiology; ablation techniques; embolization; high-intensity focused ultrasound ablation bone metastases; imaging; interventional radiology; ablation techniques; embolization; high-intensity focused ultrasound ablation
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MDPI and ACS Style

Papalexis, N.; Parmeggiani, A.; Peta, G.; Spinnato, P.; Miceli, M.; Facchini, G. Minimally Invasive Interventional Procedures for Metastatic Bone Disease: A Comprehensive Review. Curr. Oncol. 2022, 29, 4155-4177. https://doi.org/10.3390/curroncol29060332

AMA Style

Papalexis N, Parmeggiani A, Peta G, Spinnato P, Miceli M, Facchini G. Minimally Invasive Interventional Procedures for Metastatic Bone Disease: A Comprehensive Review. Current Oncology. 2022; 29(6):4155-4177. https://doi.org/10.3390/curroncol29060332

Chicago/Turabian Style

Papalexis, Nicolas, Anna Parmeggiani, Giuliano Peta, Paolo Spinnato, Marco Miceli, and Giancarlo Facchini. 2022. "Minimally Invasive Interventional Procedures for Metastatic Bone Disease: A Comprehensive Review" Current Oncology 29, no. 6: 4155-4177. https://doi.org/10.3390/curroncol29060332

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