Background: Gastrointestinal (gi) symptoms are the most notable side effects of chemotherapeutic drugs; such symptoms are currently treated with drugs. In the present study, we investigated the effect of acupuncture on gi symptoms induced by chemotherapy in patients with advanced gastric cancer. Methods: A cohort of 56 patients was randomly divided into an experimental group and a control group. All patients received combination chemotherapy with oxaliplatin–paclitaxel. Patients in the experimental group received 30 minutes of acupuncture therapy daily for 2 weeks. The frequency and duration of nausea, vomiting, abdominal pain, and diarrhea, the average days and costs of hospitalization, and quality-of-life scores were compared between the groups. Results: Nausea was sustained for 32 ± 5 minutes and 11 ± 3 minutes daily in the control and experimental groups respectively (p < 0.05). On average, vomiting occurred 2 ± 1 times daily in the experimental group and 4 ± 1 times daily in the control group (p < 0.05). Abdominal pain persisted for 7 ± 2 minutes and 16 ± 5 minutes daily in the experimental and control groups respectively (p < 0.05). On average, diarrhea occurred 1 ± 1 times daily in the experimental group and 3 ± 1 times daily in the control group (p < 0.05). The average quality-of-life score was higher in the experimental group than in the control group (p < 0.05). No adverse events were observed for the patients receiving acupuncture. Conclusions: Acupuncture, a safe technique, could significantly reduce gi symptoms induced by chemotherapy and enhance quality of life in patients with advanced gastric cancer.
Share and Cite
MDPI and ACS Style
Zhou, J.; Fang, L.; Wu, W.Y.; He, F.; Zhang, X.L.; Zhou, X.; Xiong, Z.J.
The Effect of Acupuncture on Chemotherapy-Associated Gastrointestinal Symptoms in Gastric Cancer. Curr. Oncol. 2017, 24, 1-5.
Zhou J, Fang L, Wu WY, He F, Zhang XL, Zhou X, Xiong ZJ.
The Effect of Acupuncture on Chemotherapy-Associated Gastrointestinal Symptoms in Gastric Cancer. Current Oncology. 2017; 24(1):1-5.
Zhou, J., L. Fang, W.Y. Wu, F. He, X.L. Zhang, X. Zhou, and Z.J. Xiong.
2017. "The Effect of Acupuncture on Chemotherapy-Associated Gastrointestinal Symptoms in Gastric Cancer" Current Oncology 24, no. 1: 1-5.
Article Access Statistics
For more information on the journal statistics, click here
Multiple requests from the same IP address are counted as one view.