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Current Oncology
Volume 14
Issue 6
10.3747/co.2007.158
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Current Oncology is published by MDPI from Volume 28 Issue 1 (2021). Previous articles were published by another publisher in Open Access under a CC-BY (or CC-BY-NC-ND) licence, and they are hosted by MDPI on mdpi.com as a courtesy and upon agreement with Multimed Inc..
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Article

Role of Vaccine Therapy in Cancer: Biology and Practice

by
J. Schlom
1,*,
J. L. Gulley
1,2 and
P. M. Arlen
1,2
1
Laboratory of Tumor Immunology and Biology, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA
2
Medical Oncology Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA
*
Author to whom correspondence should be addressed.
Curr. Oncol. 2007, 14(6), 238-245; https://doi.org/10.3747/co.2007.158
Submission received: 2 September 2007 / Revised: 3 October 2007 / Accepted: 5 November 2007 / Published: 1 December 2007

Abstract

Vaccines constitute a potential new therapeutic approach for a range of human cancers. Unlike other therapeutics, vaccines initiate a dynamic process in the host immune system that can be exploited with subsequent therapies. Indeed, recent preclinical and clinical studies with cancer vaccines have provided evidence that this unique therapeutic modality should lead to consideration of new paradigms in both clinical trial design and endpoints and in combination therapies. The present article reviews and sets out a rationale for these new paradigms, with a focus on prostate cancer.
Keywords: immunotherapy; vaccine; clinical protocols; prostate cancer; cancer vaccine; combination therapy immunotherapy; vaccine; clinical protocols; prostate cancer; cancer vaccine; combination therapy

Share and Cite

MDPI and ACS Style

Schlom, J.; Gulley, J.L.; Arlen, P.M. Role of Vaccine Therapy in Cancer: Biology and Practice. Curr. Oncol. 2007, 14, 238-245. https://doi.org/10.3747/co.2007.158

AMA Style

Schlom J, Gulley JL, Arlen PM. Role of Vaccine Therapy in Cancer: Biology and Practice. Current Oncology. 2007; 14(6):238-245. https://doi.org/10.3747/co.2007.158

Chicago/Turabian Style

Schlom, J., J. L. Gulley, and P. M. Arlen. 2007. "Role of Vaccine Therapy in Cancer: Biology and Practice" Current Oncology 14, no. 6: 238-245. https://doi.org/10.3747/co.2007.158

APA Style

Schlom, J., Gulley, J. L., & Arlen, P. M. (2007). Role of Vaccine Therapy in Cancer: Biology and Practice. Current Oncology, 14(6), 238-245. https://doi.org/10.3747/co.2007.158

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