The Association of Obesity and Overweight with Executive Functions in Community-Dwelling Older Women
Abstract
:1. Introduction
2. Methodology
2.1. Study Design
2.2. Sample Size Calculation
2.3. Participants and Eligibility
2.4. Measurements
2.4.1. Main Characteristics of the Participants
2.4.2. Assessment of Executive Functions
2.4.3. Anthropometric Measurements
2.4.4. Covariates
2.5. Statistical Analysis
3. Results
4. Discussion
5. Conclusions
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Acknowledgments
Conflicts of Interest
References
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Variable | Normal Weight (n = 45) | Overweight (n = 98) | Obesity (n = 81) | p-Value |
---|---|---|---|---|
Age (years) | 65.69 ± 3.70 | 66.26 ± 4.27 | 65.37 ± 4.03 | 0.344 |
Weight | 55.58 ± 4.66 | 67.74 ± 4.70 a | 80.64 ± 7.48 a,b | <0.001 |
Height | 157.13 ± 5.46 | 157.61 ± 4.96 | 155.11 ± 4.10 a,b | 0.028 |
BMI (kg/m2) | 22.53 ± 1.70 | 27.26 ± 1.37 a | 33.51 ± 2.89 a,b | <0.001 |
WC (cm) | 82.63 ± 3.96 | 94.20 ± 2.10 a | 102.74 ± 9.78 a,b | <0.001 |
MMSE | 26.28 ± 1.86 | 26.28 ± 1.88 | 26.27 ± 1.85 | 0.066 |
Education level | <0.001 | |||
Illiterate | 1 (2.2) | 1 (1.0) | 20 (24.7) a,b | |
1–4 years | 21 (46.7) | 51 (52.0) a | 61 (75.3) a,b | |
5–8 years | 5 (11.1) | 39 (39.8) a | ------- | |
Over 8 years | 18 (40.0) | 7 (7.1) | ------- | |
Marital status n (%) | ||||
Married/common-law | 44 (97.7) | 96 (98.0) | 80 (98.8) | 0.528 |
Widowed | 1 (2.3) | 2 (2.0) | 1 (1.2) | |
Household income, n (%) | ||||
USD ≤ 210.00 | 4 (8.9) | 5 (5.1) | 4 (5.0) | 0.621 |
USD 211.00–420.00 | 40 (88.9) | 91 (92.9) | 75 (92.6) | |
USD 421.00–630.00 | 1 (2.2) | 1 (1.0) | 1 (1.2) | |
USD 631.00–840.00 | ----- | 1 (1.0) | 1 (1.2) | |
USD ≥ 841.00 | ----- | ----- | ----- | |
Medication | 0.002 | |||
1–4 types n (%) | 33 (73.3) | 67 (68.4) a | 39 (48.1) a,b | |
>4 types n (%) | 12 (26.7) | 31 (31.6) a | 42 (51.9) a,b | |
Comorbidities | ||||
Diabetes mellitus | <0.001 † | |||
Yes n (%) | 7 (15.6) | 54 (55.1) | 23 (28.4) | |
Hypertension | 0.169 | |||
Yes n (%) | 24 (53.3) | 48 (49.0) | 51 (63.0) |
Variable | BMI | Age | WC | Education | TMT-A | TMT-B |
---|---|---|---|---|---|---|
Age | −0.300 * | |||||
WC | 0.560 ** | −0.180 * | ||||
Education | −0.500 * | −0.370 ** | −0.350 * | |||
TMT-A | 0.450 ** | −0.320 * | 0.360 ** | −0.380 ** | ||
TMT-B | 0.450 ** | −0.400 * | 0.310 ** | −0.370 ** | 0.680 *** | |
TMT B-A | 0.480 ** | −0.432 * | 0.380 ** | −0.412 ** | 0.701 *** | 0.711 *** |
Variable | Normal Weight (n = 45) | Overweight (n = 98) | Obesity (n = 81) | p-Value |
---|---|---|---|---|
Model 1 | ||||
TMT-A | 58.78 ± 12.37 | 64.85 ± 7.43 | 77.56 ± 11.02 | 0.041 |
TMT-B | 152.95 ± 29.54 | 159.31 ± 48.57 | 213.10 ± 42.55 | 0.130 |
ΔTMT (B-A) | 94.17 ± 57.43 | 94.46 ± 26.32 | 135.55 ± 42.53 | 0.670 |
Model 2 | ||||
TMT-A | 59.57 ± 11.68 | 65.24 ± 7.71 | 78.68 ± 10.95 | 0.028 |
TMT-B | 156.66 ± 28.60 | 160.65 ± 48.38 | 216.27 ± 37.55 | 0.027 |
ΔTMT (B-A) | 97.10 ± 55.46 | 95.41 ± 24.55 | 137.60 ± 36.67 | 0.048 |
Variable | Normal (n = 89) | Abdominal Obesity (n = 135) | p-Value |
---|---|---|---|
Model 1 | |||
TMT-A | 63.50 ± 1.33 | 68.33 ± 1.08 | <0.012 |
TMT-B | 171.60 ± 5.19 | 179.48 ± 4.21 | 0.039 |
ΔTMT (B-A) | 108.10 ± 4.74 | 111.15 ± 3.85 | 0.400 |
Model 2 | |||
TMT-A | 64.19 ± 1.25 | 69.88 ± 1.01 | 0.002 |
TMT-B | 174.20 ± 4.87 | 183.76 ± 3.95 | 0.130 |
ΔTMT (B-A) | 110.01 ± 4.63 | 108.88 ± 5.78 | 0.670 |
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Nascimento, M.d.M.; Kliegel, M.; Silva, P.S.T.; Rios, P.M.B.; Nascimento, L.d.S.; Silva, C.N.; Ihle, A. The Association of Obesity and Overweight with Executive Functions in Community-Dwelling Older Women. Int. J. Environ. Res. Public Health 2023, 20, 2440. https://doi.org/10.3390/ijerph20032440
Nascimento MdM, Kliegel M, Silva PST, Rios PMB, Nascimento LdS, Silva CN, Ihle A. The Association of Obesity and Overweight with Executive Functions in Community-Dwelling Older Women. International Journal of Environmental Research and Public Health. 2023; 20(3):2440. https://doi.org/10.3390/ijerph20032440
Chicago/Turabian StyleNascimento, Marcelo de Maio, Matthias Kliegel, Paloma Sthefane Teles Silva, Pâmala Morais Bagano Rios, Lara dos Santos Nascimento, Carolina Nascimento Silva, and Andreas Ihle. 2023. "The Association of Obesity and Overweight with Executive Functions in Community-Dwelling Older Women" International Journal of Environmental Research and Public Health 20, no. 3: 2440. https://doi.org/10.3390/ijerph20032440