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Review

Surface Treatment of the Dental Implant with Hyaluronic Acid: An Overview of Recent Data

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Department of Biomedical and Dental Sciences, Morphological and Functional Images, University of Messina, 98100 Messina, Italy
2
Department of Implantology, Faculty of Dentistry, University of Aldent, 1000 Tirana, Albania
3
Multidisciplinary Department of Medical-Surgical and Odontostomatological Specialties, University of Campania “Luigi Vanvitelli”, 80121 Naples, Italy
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Laboratory of Microbiology and Virology, School of Doctorate in Clinical and Experimental Medicine, University of Modena and Reggio Emilia, Via G. Campi 287, 41125 Modena, Italy
5
Department of Dental Therapy, Faculty of Dental Medicine, University of Medicine, 1005 Tirana, Albania
*
Author to whom correspondence should be addressed.
Academic Editor: Iole Vozza
Int. J. Environ. Res. Public Health 2021, 18(9), 4670; https://doi.org/10.3390/ijerph18094670
Received: 10 March 2021 / Revised: 22 April 2021 / Accepted: 25 April 2021 / Published: 27 April 2021
(This article belongs to the Special Issue Oral Pathologies and Their Impact on Public Health)
Recently, interest has grown by focusing on the evaluation of a molecule already produced in the human body such as hyaluronic acid (HA), as an application to the surface of the titanium implant. Its osteo-conductive characteristics and positive interaction with the progenitor cells responsible for bone formation, consequently, make it responsible for secondary stability. The aim of this work was to analyze the various surface treatments in titanium implants, demonstrating that the topography and surface chemistry of biomaterials can correlate with the host response; also focusing on the addition of HA to the implant surface and assessing the biological implications during early stages of recovery. Used as a coating, HA acts on the migration, adhesion, proliferation and differentiation of cell precursors on titanium implants by improving the connection between implant and bone. Furthermore, the improvement of the bioactivity of the implant surfaces through HA could therefore facilitate the positioning of the dental prosthesis precisely in the early loading phase, thus satisfying the patients’ requests. It is important to note that all the findings should be supported by further experimental studies in animals as well as humans to evaluate and confirm the use of HA in any field of dentistry. View Full-Text
Keywords: dental implant; surface treatment; hyaluronic acid dental implant; surface treatment; hyaluronic acid
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MDPI and ACS Style

Cervino, G.; Meto, A.; Fiorillo, L.; Odorici, A.; Meto, A.; D’Amico, C.; Oteri, G.; Cicciù, M. Surface Treatment of the Dental Implant with Hyaluronic Acid: An Overview of Recent Data. Int. J. Environ. Res. Public Health 2021, 18, 4670. https://doi.org/10.3390/ijerph18094670

AMA Style

Cervino G, Meto A, Fiorillo L, Odorici A, Meto A, D’Amico C, Oteri G, Cicciù M. Surface Treatment of the Dental Implant with Hyaluronic Acid: An Overview of Recent Data. International Journal of Environmental Research and Public Health. 2021; 18(9):4670. https://doi.org/10.3390/ijerph18094670

Chicago/Turabian Style

Cervino, Gabriele, Agron Meto, Luca Fiorillo, Alessandra Odorici, Aida Meto, Cesare D’Amico, Giacomo Oteri, and Marco Cicciù. 2021. "Surface Treatment of the Dental Implant with Hyaluronic Acid: An Overview of Recent Data" International Journal of Environmental Research and Public Health 18, no. 9: 4670. https://doi.org/10.3390/ijerph18094670

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