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Influences of Ketogenic Diet on Body Fat Percentage, Respiratory Exchange Rate, and Total Cholesterol in Athletes: A Systematic Review and Meta-Analysis

by 1 and 2,*
1
Graduate School of Education, Chung-Ang University, Seoul 06974, Korea
2
Sports Medicine and Science, Kyung Hee University, Gyeonggi-do 17104, Korea
*
Author to whom correspondence should be addressed.
Academic Editors: Paul B. Tchounwou and Antonella Agodi
Int. J. Environ. Res. Public Health 2021, 18(6), 2912; https://doi.org/10.3390/ijerph18062912
Received: 17 January 2021 / Revised: 20 February 2021 / Accepted: 11 March 2021 / Published: 12 March 2021
(1) Background: The purpose of the current meta-analysis was to investigate any positive or negative effects of ketogenic diets in athletes and provide an assessment of the size of these effects. (2) Methods: Databases were used to select relevant studies up to January 2021 regarding the effects of ketogenic diets in athletes. Inclusion criteria were as follows: data before and after ketogenic diet use, being randomized controlled trials and presenting ketogenic diets and assessments of ketone status. Study subjects were required to be professional athletes. Review studies, pilot studies, and studies in which non-athletes were included were excluded from this meta-analysis. The outcome effect sizes in these selected studies were calculated by using the standardized mean difference statistic. (3) Results: Eight studies were selected for this meta-analysis. Athletes who consumed the ketogenic diet had reduced body fat percentages, respiratory exchange rates, and increased total cholesterol compared to athletes who did not consume this diet. However, body mass index, cardiorespiratory fitness, heart rate, HDL cholesterol, glucose level, and insulin level were unaffected by the diet. (4) Conclusions: Ketogenic diets had a beneficial effect by decreasing body fat percentage, but athletes with high total cholesterol level need to be monitored when instituting a ketogenic diet. Our study sample size was limited; therefore, additional studies may be needed to confirm the current findings. Further studies need to be conducted on changes in LDL cholesterol, HDL cholesterol, total cholesterol and ratio of LDL to HDL cholesterol. View Full-Text
Keywords: athletes; ketogenic diet; meta-analysis athletes; ketogenic diet; meta-analysis
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MDPI and ACS Style

Lee, H.S.; Lee, J. Influences of Ketogenic Diet on Body Fat Percentage, Respiratory Exchange Rate, and Total Cholesterol in Athletes: A Systematic Review and Meta-Analysis. Int. J. Environ. Res. Public Health 2021, 18, 2912. https://doi.org/10.3390/ijerph18062912

AMA Style

Lee HS, Lee J. Influences of Ketogenic Diet on Body Fat Percentage, Respiratory Exchange Rate, and Total Cholesterol in Athletes: A Systematic Review and Meta-Analysis. International Journal of Environmental Research and Public Health. 2021; 18(6):2912. https://doi.org/10.3390/ijerph18062912

Chicago/Turabian Style

Lee, Hyun S., and Junga Lee. 2021. "Influences of Ketogenic Diet on Body Fat Percentage, Respiratory Exchange Rate, and Total Cholesterol in Athletes: A Systematic Review and Meta-Analysis" International Journal of Environmental Research and Public Health 18, no. 6: 2912. https://doi.org/10.3390/ijerph18062912

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