Therapeutic Benefits of Balneotherapy on Quality of Life of Patients with Rheumatoid Arthritis: A Systematic Review
Abstract
:1. Introduction
2. Materials and Methods
2.1. Elegibility
2.2. Outcomes
2.3. Information Sources
2.4. Search Strategy
2.5. Selection Process
2.6. Risk of Bias
3. Results
3.1. Descriptive Study
3.2. Interventions
3.3. Outcome
3.4. Risk of Bias
4. Discussion
4.1. Limitations and Strenghts
4.2. Clinical Implications
5. Conclusions
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Conflicts of Interest
Appendix A. Search Strategy
Appendix A.1. Pubmed
Appendix A.2. Scopus
Appendix A.3. Web of Sciencie
Appendix A.4. Cochrane Library
References
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Author, Year | Desing | Participant | Intervention | Scales | Secondary Outcomes | Results |
---|---|---|---|---|---|---|
Allam, N.M., et al. [24] 2018 | RCT | N = 30 IG; n = 15 CG; n = 15 | IG: Siwan therapy 7 days of hot sand baths for 20 min and massage with olive oil CG: standard physiotherapy treatment | HAQ | Pain (VAS) | The scale score were decreased significantly compared with baseline in spa group but not in control group |
Annegret, F., et al. [25] 2013 | RCT | N = 98 IG; n = 48 CG; n = 50 | 3–4 weeks of intervetion IG: 12 total radon baths every 2 or 3 days in spedificil locations for 20 min a day CG: 12 tap water baths with artificial CO2 for 20 min | HAQ | Pain (VAS) SF-12 | There is a significant improvement in the HAQ scores of the intervetion group versus the control group |
Annegret, F., et al. [26] 2000 | RCT | N = 60 IG; n = 30 CG; n = 30 | 4 weeks of intervetion IG: 15 total radon baths for 20 min a day CG: 15 baths in tap water baths with artificial CO2 for 20 min | AIMS | Pain (VAS) Keitel funcional test (KFI) | Significant differences were found in terms of the improvement in the result of the AIMS scale in the intervention group at 3 and 6 months of follow-up. |
Karagülle, M., et al. [27] 2017 | RCT | N = 37 IG; n = 15 CG; n = 22 | 2 weeks of intervetion IG: 12 balneotherapy sessions in mineral water for 20 min a day CG: standard drug treatment | HAQ | Pain (VAS) Disease Activity Score (DAS28) Patient global assessment (VAS) Biochemical analysis | HAQ scores were significantly reduced compared to baseline results in the intervention group, but not in the control group |
Karagülle, M., et al. [28] 2018 | CRCT | N first period = 15 N second period = 22 | 2 weeks of intervetion IG: 12 balneotherapy sessions in mineral water for 20 min a day CG: standard drug treatment | HAQ | Pain (VAS) Disease Activity Score (DAS28) Patient global assessment (VAS) | A significant difference was found in the intervention group at 3 months; however, there were no significant differences at 6 months |
Santos, I., et al. [29] 2016 | RCT | N = 44 IG; n = 22 CG; n = 22 | 21 days of intervention IG: two treatments on alternate days. Treatment 1 consisted of sulphur baths of 30 min and underwater exercises. Treatment 2 consisted of sulphur baths of 20 min and underwater jets for 10 min in painful joints CG: standard drug treatment | HAQ | Global health assessment (VAS) Pain (VAS) Quality of life (VAS) Fatigue (VAS) Disease Activity Score (DAS28) | HAQ improved significantly in the intervention group compared to the control group |
Sukenik, S., et al. [30] 1990 | RCT | N = 40 4 groups of 10 patiens each one | 2 weeks fo intervetion Group 1: daily mud packs in full body for 20 min a day Group 2: daily sulphur baths for 20 min a day Group 3: combination of daily mud packs and daily sulphur baths Group 4: control, without treatment | Patient assessment of disease severity | Morning stiffness Fifteen metre walk time Circunference of proximal interphalangeal joints Activities of daily living | Significant improvements were found in terms of the patient’s perception of the disease in the three treatment groups |
Author, year | Scales | Baseline Evaluation | Post-Treatment Evaluation | Follow-Up | |||||||
---|---|---|---|---|---|---|---|---|---|---|---|
Control Group | Intervention Group | Control Group | Intervetion Group | Intragroup | Intergroup | Control Group | Intervention Group | Intragroup | Intergroup | ||
Allam, N.M., et al. [24] 2018 | HAQ | 1.82 ± 0.52 | 1.75 ± 0.58 | 1.58 ± 0.67 | 0.82 ± 0.50 | p < 0.05 in intervention group | p < 0.05 in favor to intervention group | - | - | - | - |
Annegret, F., et al. [25] 2013 a | HAQ | 0.95 (0.62) | 0.93 (0.52) | 0.10 (0.29) | 0.08 (0.39) | p < 0.05 in intervention group | p > 0.05 | 3 months = 0.08(0.31) 6 months = 0.07(0.43) 9 months = 0.07(0.34) | 3 months = 0.10 (0.42) 6 months = 0.17(0.37) 9 months = 0.09 (0.45) | p > 0.05 | p < 0.05 |
Annegret, F., et al. [26] 2000 a | AIMS | 6.60 (1.10) | 6.27 (1.33) | - | - | p > 0.05 | p < 0.05 in favor to intervention group | 3 months = −0.06 (−0.34, 0.23) 6 months = −0.18 (−0.36, 0.20) | 3 months = 0.41 (0.06, 0.75) 6 months = 0.41 (0.06, 0.74) | ||
Karagülle, M., et al. [27] 2017 | HAQ | 1.43 ± 0.76 | 1.33 ± 0.68 | 2 weeks post tto. 1.23 ± 0.75 | 2 weeks post tto. 0.79 ± 0.64 | p < 0.05 in intervention group | p < 0.05 in favor to intervention group | - | - | ||
Karagülle, M., et al. [28] 2018 a | HAQ | 0.96 (0.66, 1.99) | 1.40 (0.73, 1.83) | 2 weeks post tto. 1.10 (1.51, 1.76) | 2 weeks post tto. 0.08 (0.33, 1.13) | p < 0.05 in intervention group | p < 0.05 in favor to intervention group | 3 months = 1.00 (0.51, 1.76) 6 months = 1.10 (0.41, 1.55) | 3 months = 0.60 (0.40, 0.98) 6 months = 0.65 (0.38, 1.43) | ||
Santos, I., et al. [29] 2016 a | HAQ | 1.34 (0.97, 1.7) | 1.50 (1.24, 1.76) | Difference between groups 0.37 (0.09, 0.64) | - | p < 0.05 | Difference between groups at 3 months 0.44 (0.15, 0.72) | p < 0.05 | |||
Sukenik, S., et al. [30] 1990 b | Patient’s self assessment of the disease | 5.5 | Mud packs 4.1 | Mud packs 6.5 | 6.1 | p < 0.05 in the three treatment groups | 3 months Mud packs 5.7 | 3 months 5.7 | |||
Sulphur baths 5.0 | Sulphur baths 6.4 | 3 months Sulphur baths 6.3 | |||||||||
Combination 4.8 | Combination 7.0 | 3 months Combination 5.7 |
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Fernandez-Gonzalez, M.; Fernandez-Lao, C.; Martin-Martin, L.; Gonzalez-Santos, A.; Lopez-Garzon, M.; Ortiz-Comino, L.; Lozano-Lozano, M. Therapeutic Benefits of Balneotherapy on Quality of Life of Patients with Rheumatoid Arthritis: A Systematic Review. Int. J. Environ. Res. Public Health 2021, 18, 13216. https://doi.org/10.3390/ijerph182413216
Fernandez-Gonzalez M, Fernandez-Lao C, Martin-Martin L, Gonzalez-Santos A, Lopez-Garzon M, Ortiz-Comino L, Lozano-Lozano M. Therapeutic Benefits of Balneotherapy on Quality of Life of Patients with Rheumatoid Arthritis: A Systematic Review. International Journal of Environmental Research and Public Health. 2021; 18(24):13216. https://doi.org/10.3390/ijerph182413216
Chicago/Turabian StyleFernandez-Gonzalez, Maria, Carolina Fernandez-Lao, Lydia Martin-Martin, Angela Gonzalez-Santos, Maria Lopez-Garzon, Lucia Ortiz-Comino, and Mario Lozano-Lozano. 2021. "Therapeutic Benefits of Balneotherapy on Quality of Life of Patients with Rheumatoid Arthritis: A Systematic Review" International Journal of Environmental Research and Public Health 18, no. 24: 13216. https://doi.org/10.3390/ijerph182413216