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Communication

COVID-19 among Healthcare Workers: A Prospective Serological-Epidemiological Cohort Study in a Standard Care Hospital in Rural Germany

1
Department of Public Health, Institute of Health, Brandenburg University of Technology Cottbus-Senftenberg, 01968 Senftenberg, Germany
2
Institute for Clinical Chemistry, Laboratory Diagnostics and Microbiology, Klinikum Niederlausitz GmbH, 01968 Senftenberg, Germany
3
Institute of Microbiology and Virology, Brandenburg Medical School Theodor Fontane, 01968 Senftenberg, Germany
*
Author to whom correspondence should be addressed.
Academic Editor: Dietmar Knopp
Int. J. Environ. Res. Public Health 2021, 18(20), 10999; https://doi.org/10.3390/ijerph182010999
Received: 16 August 2021 / Revised: 5 October 2021 / Accepted: 12 October 2021 / Published: 19 October 2021
(This article belongs to the Topic Burden of COVID-19 in Different Countries)
Healthcare workers (HCW) play a vital role in the SARS-CoV-2 pandemic control. The aim of this study was to assess the prevalence of SARS-CoV-2 antibodies and the risk of COVID-19 infections in a cohort of HCW from four different risk groups (from intensive care unit to administration) of a hospital of a primary care level in rural Germany. The outcomes were monthly measures of antibody seroprevalence over a period of 6 months. Overall, a seroprevalence of 13.41% was determined, with significantly higher prevalence rates among HCW working in areas with more frequent contact to confirmed or suspected cases (30.30%, p = 0.003). The group specific differences in the risk of infection from COVID-19 were detected, as HCW groups with frequent exposure seemed to have an increased risk (RR = 3.18, p = 0.02; CI95 1.09–9.24). The findings contribute to the epidemiological understanding of the virus spread in an unvaccinated population group, which is highly relevant for the pandemic management. View Full-Text
Keywords: SARS-CoV-2; immunity; antibody; healthcare; staff; COVID-19; seroprevalence; pandemic SARS-CoV-2; immunity; antibody; healthcare; staff; COVID-19; seroprevalence; pandemic
MDPI and ACS Style

Hoffmann, S.; Schiebel, J.; Hufert, F.; Gremmels, H.-D.; Spallek, J. COVID-19 among Healthcare Workers: A Prospective Serological-Epidemiological Cohort Study in a Standard Care Hospital in Rural Germany. Int. J. Environ. Res. Public Health 2021, 18, 10999. https://doi.org/10.3390/ijerph182010999

AMA Style

Hoffmann S, Schiebel J, Hufert F, Gremmels H-D, Spallek J. COVID-19 among Healthcare Workers: A Prospective Serological-Epidemiological Cohort Study in a Standard Care Hospital in Rural Germany. International Journal of Environmental Research and Public Health. 2021; 18(20):10999. https://doi.org/10.3390/ijerph182010999

Chicago/Turabian Style

Hoffmann, Stephanie, Juliane Schiebel, Frank Hufert, Heinz-Detlef Gremmels, and Jacob Spallek. 2021. "COVID-19 among Healthcare Workers: A Prospective Serological-Epidemiological Cohort Study in a Standard Care Hospital in Rural Germany" International Journal of Environmental Research and Public Health 18, no. 20: 10999. https://doi.org/10.3390/ijerph182010999

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