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Article

PM2.5 and Diabetes in the Japanese Population

Center for Clinical Academia, Graduate School of Public Health, Luke’s International University, 5th Floor 3-6-2, Tsukiji, Chuo-ku, Tokyo 104-0045, Japan
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Academic Editor: Omorogieva Ojo
Int. J. Environ. Res. Public Health 2021, 18(12), 6653; https://doi.org/10.3390/ijerph18126653
Received: 13 April 2021 / Revised: 7 June 2021 / Accepted: 9 June 2021 / Published: 21 June 2021
Growing evidence suggests that PM2.5 is associated with diabetes mellitus (DM). Although DM is a major public health concern, there has not yet been a study of this association in Japan. We used health examination data from 66,885 individuals in Tokyo, Japan 2005–2019. Cox proportional hazards models were used to evaluate an association between annual exposure to PM2.5 and glycated hemoglobin A1c (HbA1c), or fasting plasma glucose (FPG). An increase of 1 μg/m3 in the annual average of PM2.5 concentration was associated (HR = 1.029; 95% CI = 1.004–1.055) with an increase in diabetes (incident + prevalent). For incident DM, a greater PM2.5 level was associated with more DM (HR = 1.029; 95% CI, 1.003–1.055). Compared to HbA1c, FPG showed a stronger association with the annual exposure to PM2.5 (HR = 1.065; 95% CI, 1.040–1.091). We found that greater exposure to PM2.5 in the long-term was associated with an increased risk of diabetes, and that the magnitude of association became stronger as the exposure duration increased. Omorogieva Ojo View Full-Text
Keywords: diabetes mellitus; particulate matter; PM2.5; air pollution; Japan; Tokyo diabetes mellitus; particulate matter; PM2.5; air pollution; Japan; Tokyo
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MDPI and ACS Style

Lee, M.; Ohde, S. PM2.5 and Diabetes in the Japanese Population. Int. J. Environ. Res. Public Health 2021, 18, 6653. https://doi.org/10.3390/ijerph18126653

AMA Style

Lee M, Ohde S. PM2.5 and Diabetes in the Japanese Population. International Journal of Environmental Research and Public Health. 2021; 18(12):6653. https://doi.org/10.3390/ijerph18126653

Chicago/Turabian Style

Lee, Mihye, and Sachiko Ohde. 2021. "PM2.5 and Diabetes in the Japanese Population" International Journal of Environmental Research and Public Health 18, no. 12: 6653. https://doi.org/10.3390/ijerph18126653

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