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Open AccessArticle

High Level of Physical Activity Reduces the Risk of Renal Progression in Hypertensive Patients

1
Department of Leisure Industry and Health Promotion, National Taipei University of Nursing and Health Sciences, Taipei City 11219, Taiwan
2
Graduate Institute of Clinical Medicine, Taipei Medical University, Taipei City 11031, Taiwan
3
Department of Exercise and Health Science, National Taipei University of Nursing and Health Sciences, Taipei City 11219, Taiwan
*
Author to whom correspondence should be addressed.
Int. J. Environ. Res. Public Health 2020, 17(5), 1669; https://doi.org/10.3390/ijerph17051669
Received: 30 January 2020 / Revised: 29 February 2020 / Accepted: 1 March 2020 / Published: 4 March 2020
(This article belongs to the Collection Sport and Exercise for Health and Performance)
Physical activity has long been associated with chronic diseases. However, the association between physical activity and renal progression in hypertensive patients remains unclear. This study investigated the relationship between the level of physical activity and renal function in hypertensive patients. We analyzed 3543 patients with hypertension. Data on patients’ demographic characteristics, comorbidities, physical activity, and lifestyle characteristics were collected via questionnaires. An estimated glomerular filtration rate (eGFR) that was reduced by more than 25% from the baseline eGFR was defined as renal progression. This study divided physical activity into three levels (low, moderate, and high) based on their metabolic equivalent of tasks (METs) levels. The mean age was 63.32 ± 12.29 years. After we adjusted for covariates, renal progression was significantly higher among patients with low levels of physical activity (odds ratio (OR), 1.39; 95% confidence interval (CI), 1.01–1.90)) and moderate levels of physical activity (OR, 1.39; 95% CI, 1.04–1.86) than among patients with high levels of physical activity. We found a significant association between physical activity and renal progression in hypertensive patients, especially in elderly patients and men. Therefore, to reduce the risk of renal progression, we recommend that clinicians should encourage patients to improve their physical activity. View Full-Text
Keywords: physical activity; renal progression; hypertension physical activity; renal progression; hypertension
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MDPI and ACS Style

Chang, P.-Y.; Lyu, S.-Y.; Lin, Y.-F.; Huang, C.-C. High Level of Physical Activity Reduces the Risk of Renal Progression in Hypertensive Patients. Int. J. Environ. Res. Public Health 2020, 17, 1669. https://doi.org/10.3390/ijerph17051669

AMA Style

Chang P-Y, Lyu S-Y, Lin Y-F, Huang C-C. High Level of Physical Activity Reduces the Risk of Renal Progression in Hypertensive Patients. International Journal of Environmental Research and Public Health. 2020; 17(5):1669. https://doi.org/10.3390/ijerph17051669

Chicago/Turabian Style

Chang, Po-Ya; Lyu, Shu-Yu; Lin, Yuh-Feng; Huang, Chun-Ching. 2020. "High Level of Physical Activity Reduces the Risk of Renal Progression in Hypertensive Patients" Int. J. Environ. Res. Public Health 17, no. 5: 1669. https://doi.org/10.3390/ijerph17051669

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