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Article

Two-Phase Evaluation of a Community-Based Lifestyle Intervention for Palestinian Women in East Jerusalem: A Quasi-Experimental Study Followed by Dissemination

1
Linda Joy Pollin Cardiovascular Wellness Center for Women, Division of Cardiology, Hadassah University Medical Center, Jerusalem 91120, Israel
2
The Nutrition Division, The Israeli Ministry of Health, Jerusalem 91011002, Israel
3
Braun School of Public Health and Community Medicine, The Hebrew University of Jerusalem-Hadassah, Jerusalem 91120, Israel
*
Author to whom correspondence should be addressed.
Int. J. Environ. Res. Public Health 2020, 17(24), 9184; https://doi.org/10.3390/ijerph17249184
Submission received: 25 October 2020 / Revised: 25 November 2020 / Accepted: 2 December 2020 / Published: 9 December 2020

Abstract

:
Palestinian-Arab women are at increased risk of cardiovascular disease due to high prevalence of diabetes and other risk factors. The current study investigates the effectiveness of an intensive group-based intervention on lifestyle habits that can prevent diabetes and cardiovascular disease. To that end, we conducted a group-based intervention based on the diabetes prevention program in two consecutive phases. The first phase consisted of a quasi-experimental study and the second phase included community-wide dissemination, with a 6-month follow-up. Findings from the quasi-experiment indicate increased consumption of fruit, vegetables and whole grains, weight reduction (−2.21 kg, p < 0.01), and a significant increase in the average daily steps in the intervention group (from 4456 to 6404). Findings from the dissemination indicate that average daily vegetables consumption increased from 1.76 to 2.32/day as did physical activity and average daily steps (from 4804 to 5827). There was a significant reduction in blood pressure, total cholesterol and LDL. These gains were sustained over 6 months following the intervention. This community-based, culturally adapted, health-promotion intervention led to improved nutrition and physical activity which were maintained after 6 months. Collaboration with community centers and local community partners created an effective channel for dissemination of the program to pre-clinical individuals.

1. Introduction

There has been a marked increase in the burden of non-communicable diseases (NCDs) in the Arab world, including diabetes and cardiovascular diseases (CVD) [1]. With rapid urbanization, increased sedentary lifestyle and obesity contribute to these trends [2]. Palestinian-Arab women living in East Jerusalem (EJ) comprise a particularly high-risk population. In 2006, the prevalence of diabetes in EJ was 41% among men and 64% among women, compared to 29% among Jewish men and 42% among Jewish women in Israel [3]. Some of this discrepancy is due to reduced health care utilization [4], dietary differences, and a high prevalence of obesity among Palestinian-Arab women [5]. Arab women in EJ are at higher risk for physical inactivity compared to both their Jewish counterparts and Arab men [6]. Additionally, diabetic patients living in EJ report receiving less counselling regarding nutrition, physical activity (PA) and foot care than their Jewish counterparts [7].
Reduction in behavioral risk factors such as smoking, physical inactivity, and low fruit and vegetable consumption has been associated with decreased risk of death from NCDs [8]. The World Health Organization (WHO) has recognized the need for effective evidence-based interventions to promote healthy nutrition and PA to reduce the burden of NCDs [9]. Interventions aimed at reducing these risk factors at the community level may be the most cost-effective methods for prevention of major NCDs [10]. Community-based programs are found to improve nutritional behaviors, weight loss and prevent diabetes [11]. A systematic review of community-based interventions targeting secondary prevention of CVD found that these interventions are effective in promoting healthy behaviors including PA [12]. Similarly, a meta-analysis of 36 studies found that multifactorial lifestyle-interventions can drastically reduce multiple risk indicators such as blood pressure, cholesterol and waist circumference in 6 months, and can increase PA at 12-month follow-ups [13]. The landmark diabetes prevention program (DPP) is recognized as one of the most effective NCD prevention interventions. The DPP compared a lifestyle intervention targeting modest weight loss through dietary changes and increased PA to treatment with metformin or standard care. Target outcomes included the prevention or delay of diabetes development in pre-diabetic adults. When compared to standard care, participants in the lifestyle intervention group had a 27% reduction in the incidence of diabetes versus an 18% reduction in the metformin group, with a mean follow-up of 15 years [14]. A systematic review of DPP translational programs concluded that the DPP has been successful in its community and cultural adaptations [15]. Additionally, the DPP-like programs were found to be cost-effective among high-risk populations when delivered to groups in community or primary care settings [16].
Despite their higher risk for diabetes and cardiovascular disease, there are limited reports of lifestyle interventions in Arabic-speaking populations [17]. This study sought to evaluate a culturally adapted, community-based group lifestyle intervention based on the DPP, targeting nutrition and physical activity in Palestinian-Arab women.

2. Materials and Methods

The community-based lifestyle intervention (CBLI) was constructed based on publicly available material from the DPP [18]. The content was translated and modified to the specific cultural and religious sensitivities of Palestinian society. The material was piloted in a 12-session program with 38 women from EJ. This program was then further adapted into the present CBLI which consists of 20 group-based, weekly sessions of 3 h each, with 2 h of interactive lectures and one h of aerobic exercise. The final curriculum included the Mediterranean diet (MD), PA, cardiovascular health literacy as well as behavioral self-regulation techniques (goal setting, self-monitoring) and conscious eating.
This study included a 2-stage evaluation (Figure 1). Phase 1: A quasi-experimental study was conducted from June to December 2016. Two community centers in EJ (the Old City center and the Zur-Baher center) were identified as candidates for the intervention. These community centers were located in neighborhoods that were distant enough from each other to prevent treatment contamination and potential bias attributed to treatment awareness. Upon initiation of the study, baseline data were collected through self-report questionnaires and direct measurement from all participants at both sites by trained staff. The Zur-Baher community center was assigned to the intervention first due to logistic considerations and the Old City center was assigned to a delayed intervention, serving as a comparison group. Post-intervention data were collected at the final session of the 6-month intervention. For the comparison group, post-intervention data were similarly collected at the community center, after which, all participants were invited to participate in the intervention during the study’s second phase.
Phase 2: In this phase, we evaluated the dissemination of the intervention program in four community centers using a before–after program review design. Minor changes were made in the intervention as a result of feedback and process evaluation of the first phase of the study. In this phase, data were collected at baseline, after completion of the program, and at 6-month follow-up. After completion of the intervention, program managers maintained contact with the participants through group discussions using the free instant messaging mobile application “WhatsApp”, to encourage maintenance of health behaviors. Process evaluation and quality assurance in both phases were conducted through registration of attendance at each session and checklist-guided random site visits by study staff. In addition, participants provided monthly feedback on the program through a group discussion.
Recruitment consisted of inviting women who attended the community center on a regular basis to apply. Inclusion criteria included female gender, age 18 or over, and the ability to commit to the intervention timetable. Exclusion criteria included serious mental or physical illness that would hinder their ability to participate in a physical activity or nutrition program.

2.1. Measures

MD adherence scale items were adapted from the ATTICA study [19] including an assessment of daily average consumption of whole grains, vegetables, fruits, legumes, olive-oil and low-fat dairy products. “Western Diet” food items were assessed through a self-report questionnaire asking about consumption of sweet drinks, sweets and refined grains [20,21]. Average daily steps (ADS) were assessed in the intervention group only, using a validated pedometer (Omron Model HJ-320) [22]. Measures included ADS count over 7 days, and percentage change in ADS. Body mass index (BMI) was calculated by measuring weight (kg) on a calibrated scale (F-168, Xinfu Household Electronics, Zhongshan, Guangdong, China), and height (cm) was measured using mechanical measuring tape (ADE, MZ10017) for each participant. Blood Pressure (BP) was measured while participants were seated, using an electronic apparatus (HM-50, Visocor). BP scores were calculated by averaging two consecutive measurements, with 5 min of rest between each reading. All tests were performed on site by trained research staff including a nurse. In phase 2, PA outcomes were assessed by a questionnaire translated and culturally adapted from the Healthy Heart Score Study [23]. Questionnaires were translated by a translator whose mother tongue is Arabic and has expertise in health and medical terminology. All translations were reviewed independently by a public health professional whose mother tongue is Arabic. Outcomes included the percentage change in PA and percentage of participants who achieved 150 min of moderate PA. In the dissemination phase, blood tests for glycated hemoglobin A1C (HbA1c), LDL, triglycerides, HDL, non-HDL cholesterol were obtained by blood tests from the participants’ health plan, or using capillary whole blood obtained on finger stick through a cartridge-based latex agglutination inhibition assay (Cobas B101 point of care device, Roche Diagnostics, Basel, Switzerland).
All participants gave their informed consent for inclusion before they participated in the study. The study was conducted in accordance with the Declaration Helsinki, and the protocol was approved by the institutional review board (Helsinki Committee) of Hadassah University Medical Center (quasi-experiment: HMO-0257-13, dissemination: HMO-0585-18).

2.2. Statistical Analysis

Data were analyzed using the Generalized Estimating Equations (GEE) model (SPSS V.24.0, IBM Corp., 2017). The GEE model allows the utilization of a subject’s multiple responses in multiple time frames [24]. The full information of maximum likelihood approach is applied in GEE similar to its application in general linear modelling when data include missing values, thus enabling the use of all data collected, rather than losing data with missing values [25]. T-test and χ2 test were used to compare demographic data between groups.

3. Results

3.1. Quasi-Experiment

In total, 38 women agreed to participate in the intervention and 22 agreed to participate in the comparison group. Attendance records found that 68.5% of intervention participants attended at least 80% of the sessions. Of the participants in the experimental group, 71% completed the post-intervention data collection, and 60% of the comparison group completed the evaluation. The baseline characteristics of the participants are presented in Table 1. There was a higher percentage of married women and increased frequency of self-reported history of hypertension in the intervention group; no other statistically significant differences were seen between groups.
Table 2 presents the results of the GEE analysis. Participants in both groups increased their vegetable consumption from 1.25 servings daily at baseline to 2.01 servings post-intervention, on average. The main time effect was significant (χ2 = 6.11, p < 0.05). Increased consumption of fruit (0.73 to 1.92 average servings, p < 0.05), and whole grains were seen in the intervention group, as was weight reduction (−2.21 kg, p < 0.01). No changes were seen in the comparison group. Systolic BP was significantly lower in the intervention group at post-intervention. There was a significant increase in the ADS (from 4456 to 64,040, p < 0.001) as measured by pedometer in the intervention group, whereas, no data were available for the comparison group.

3.2. Dissemination Phase

117 women across 4 groups consented to participate in the study. Eleven participants from the comparison group in phase 1 participated in Group 1 of the dissemination phase. Baseline characteristics are presented in Table 3. Ages ranged between 19 and 71 years, and the majority of participants were 45–59 years old. Attendance of at least 80% of the sessions ranged between 60 and 83%. Overall, attendance rates observed in the dissemination phase of the intervention group ranged between 70 and 80%. Table 4 presents the GEE analysis.

4. Discussion

The high prevalence of obesity and diabetes among Arab women and men [26] accentuates the need for effective prevention and health promotion interventions. Yet, evidence on such interventions in this population is scarce [17]. The current study evaluated the effectiveness of a culturally adapted, group lifestyle intervention based on the DPP among Palestinian-Arab women in East Jerusalem. To our knowledge, this is the first study of a community-based lifestyle intervention outside of the health-system in this population. In the first phase, significant improvements in nutrition behaviors and weight were seen in the intervention compared to the comparison group. In both phases, there was a significant increase in the consumption of fruits and vegetables and the performance of PA as well as a reduction in weight, BP, and cholesterol. Improvements in nutrition and PA behaviors were sustained at six-month follow-up in phase 2.
The current body of literature on health behavior change in Arab women is small. In a randomized control trial of Arab women with metabolic syndrome in northern Israel, intervention participants had decreased waist circumference and weight as well as decreased prevalence of metabolic-syndrome compared to controls [27]. In other Arab countries in the Middle East, we found few publications on community-based interventions. In Saudi Arabia, a study of 250 pre-diabetic and obese women evaluated one-on-one biweekly education sessions by a nutritionist, which led to improved HbA1c and lipid parameters, but did not find a significant difference in BMI [28]. A DPP-based intensive lifestyle program in predominantly obese Saudi adults with prediabetes led to decreased weight and improved fasting glucose [29]. In a study of Emirati patients with type 2 diabetes, a lifestyle intervention improved glycemic control with gains that were maintained at one-year follow-up [30].
Our study’s findings are consistent with a previous randomized trial in Arab women in Israel [27]. Although the weight loss we found (−2.12 kg) is lower than that found in a meta-analysis of community-based DPPs [31] which specifically target a weight reduction of 5% (−2.32 kg), our intervention is notable for maintenance of weight loss and physical activity at the 6-month follow-up. Additionally, even small weight reduction is associated with health benefits. A DPP study by Hamman et al. [32] found that for every 1 kg of weight loss, there was a 16% reduction in risk for developing diabetes.
Maintenance of behavior changes were likely facilitated by multiple aspects of our intervention. Participants in both phases consistently reported that the pedometers motivated them to engage in more PA, which was apparent in participants’ increased ADS. Pedometers and similar monitoring devices have increased motivation and PA performance in people with a range of chronic conditions [33]. Participants’ PA maintenance following intervention completion (through the use of pedometers) may have contributed to weight-loss maintenance. Additionally, program managers maintained continuous contact with participants through WhatsApp following intervention completion. During this time, participants were encouraged to continue adherence to the MD and regular PA to prevent weight regain. Continued professional support is indicated as an effective method for weight-loss maintenance in several clinical trials [34]. This low-cost maintenance method required minimal time investment and likely contributed to participants’ behavior change maintenance.
Cultural adaptation was a central factor in this study, potentially improving outcomes. The process of adaptation requires far more than changing superficial aspects of an intervention such as language, food and images [35]. Given the unique culture of the targeted Palestinian community, our intervention modified multiple aspects of the DPP content based on participant feedback from the pilot intervention. For example, our nutrition module included local and inexpensive ingredients as well as substitutions and adaptations of traditional recipes. Staff and participants offered solutions for challenges to initiating nutrition changes, such as family opposition, traditional foods, and cultural norms. The culture of hospitality also presented complex challenges for this community, as it directly impacts the frequency and quantity of consumption; however, it also provided opportunities for exposing other community members to healthy nutrition options, increasing potential reach to the surrounding community. Additionally, incorporating PA into group sessions provided a convenient, safe and socially acceptable setting for PA performance that helped overcome both socio-religious and logistic barriers.

Study Limitations and Strengths

This study used a quasi-experimental rather than randomized design due to unexpected staffing delays at the comparison center. The decision was made to proceed with the study in a quasi-experimental fashion, so as not to delay the initiation of the study. A main challenge of a quasi-experimental design is the possibility of biased outcomes due to inherent differences between groups. In this study, socio-economic parameters were similar between the groups, suggesting that differences in social determinants of health did not influence outcome differences.
Attrition rates were very high in our comparison group follow-up in phase 1. This is a quite common phenomenon in naturalistic studies, particularly in groups that did not receive an intervention [36]. As a naturalistic study, our data collection was also somewhat challenged. The phase 1 comparison group’s follow-up data were collected at the beginning of the phase 2 intervention rather than at the end of phase 1’s intervention, creating a discrepancy in the collection time of post-data between the intervention and comparison groups. Given the logistic and staffing challenges, this timing was necessary in order to allow for complete data collection. The study was also limited by self-report measures of nutrition and PA; however, this type of data collection is often the only feasible method in community-based studies.
This study provides evidence for the feasibility of applying a community-based, culturally adapted DPP with Palestinian-Arab women, with improved outcomes in nutrition and PA. The long and careful process of program adaptation to the community’s familial and socio-cultural needs likely contributed to the program’s success. Additionally, the group setting contributed to a warm and supportive atmosphere, likely increasing participants’ engagement and motivation. This was reflected in the high weekly attendance rate and modest drop-out rates in both phases. In addition, collaborative efforts with the local community centers and consistent support from the study staff likely facilitated behavior change maintenance at the 6-month follow-up assessment.

5. Conclusions

This study describes a culturally adapted, community-based lifestyle intervention targeting high risk women that led to participants’ improved nutrition and PA. Collaboration with community centers created an effective channel for intervention dissemination, increasing community member access. Future research is warranted to better understand the challenges and opportunities for changing and maintaining positive health behaviors in this high-risk population as well as to assess long-term effectiveness. Cost-effectiveness analyses would also inform the scalability and feasibility of these interventions in similar low-resourced communities.

Author Contributions

Conceptualization, N.A., M.N.-H., R.A.B., M.K., O.K., M.D. and D.R.Z.; methodology, N.A., M.N.-H., R.A.B., M.K., O.K., M.D. and D.R.Z.; resources, D.R.Z.; data curation, N.A.; writing—original draft preparation, N.A.; writing—review and editing, D.R.Z., M.D., O.K., E.L., K.L.G.; supervision, D.R.Z.; project administration, N.A., M.N.-H., R.A.B., M.K.; funding acquisition, D.R.Z. All authors have read and agreed to the published version of the manuscript.

Funding

This work was supported by a private grant of the Pollin Family Foundation.

Acknowledgments

The authors would like to dedicate this manuscript to the memory of the late Irene Pollin, whose generosity enabled this project. We would like to thank Osama Ghanaiem from the Jerusalem municipality, Gabi Liberman and Amir Hefetz for assistance with statistical analysis, Lori Sloman for administrative assistance and the staff of the Pollin center for their continued support and insight.

Conflicts of Interest

The authors declare no conflict of interest. The funders had no role in the design of the study; in the collection, analyses, or interpretation of data; in the writing of the manuscript, or in the decision to publish the results.

References

  1. Rahim, H.F.; Sibai, A.; Khader, Y.; Hwalla, N.; Fadhil, I.; Alsiyabi, H.; Mataria, A.; Mendis, S.; Mokdad, A.H.; Husseini, A. Non-communicable diseases in the Arab world. Lancet 2014, 383, 356–367. [Google Scholar] [CrossRef]
  2. Badran, M.; Laher, I. Type II Diabetes Mellitus in Arabic-Speaking Countries. Int. J. Endocrinol. 2012, 2012, 902873. [Google Scholar] [CrossRef] [PubMed] [Green Version]
  3. Kark, J.D.; Fink, R.; Adler, B.; Goldberger, N.; Goldman, S. The incidence of coronary heart disease among Palestinians and Israelis in Jerusalem. Int. J. Endocrinol. 2006, 35, 448–457. [Google Scholar] [CrossRef] [PubMed] [Green Version]
  4. Shadmi, E. Healthcare disparities amongst vulnerable populations of Arabs and Jews in Israel. Isr. J. Health Policy Res. 2018, 7, 26. [Google Scholar] [CrossRef] [Green Version]
  5. Kalter-Leibovici, O.; Atamna, A.; Lubin, F.; Alpert, G.; Keren, M.G.; Murad, H.; Chetrit, A.; Goffer, D.; Eilat-Adar, S.; Goldbourt, U. Obesity among Arabs and Jews in Israel: A population-based study. IMAJ-RAMAT GAN- 2007, 9, 525. [Google Scholar]
  6. Bayram, T.; Donchin, M. Determinants of health behavior inequalities: A cross-sectional study from Israel. Health Promot. Int. 2019, 34, 941–952. [Google Scholar] [CrossRef]
  7. Tirosh, A.; Calderon-Margalit, R.; Mazar, M.; Stern, Z. Differences in Quality of Diabetes Care Between Jews and Arabs in Jerusalem. Am. J. Med. Qual. 2008, 23, 60–65. [Google Scholar] [CrossRef]
  8. Khaw, K.-T.; Wareham, N.; Bingham, S.; Welch, A.; Luben, R.; Day, N. Combined Impact of Health Behaviours and Mortality in Men and Women: The EPIC-Norfolk Prospective Population Study. PLoS Med. 2008, 5, e12. [Google Scholar]
  9. World Health Organization. Global Action Plan for the Prevention and Control of Noncommunicable Diseases 2013–2020; Report No.: 9241506237; WHO Document Production Services: Geneva, Switzerland, 2013. [Google Scholar]
  10. World Health Organization. The Protocol for the WHO Study on the Effectiveness of Community-Based Programmes for NCD Prevention and Control; Report No.: NMH/NPH/NCP/03.09; World Health Organization: Geneva, Switzerland, 2003. [Google Scholar]
  11. Lawlor, E.R.; Bradley, D.T.; Cupples, M.E.; Tully, M.A. The effect of community-based interventions for cardiovascular disease secondary prevention on behavioural risk factors. Prev. Med. 2018, 114, 24–38. [Google Scholar] [CrossRef] [Green Version]
  12. Ashra, N.B.; Spong, R.; Carter, P.; Davies, M.J.; Dunkley, A.; Gillies, C.; Greaves, C.; Khunti, K.; Sutton, S.; Yates, T. A Systematic Review and Meta-Analysis Assessing the Effectiveness of Pragmatic Lifestyle Interventions for the Prevention of Type 2 Diabetes Mellitus in Routine Practice; Public Health England: London, UK, 2015. [Google Scholar]
  13. Sisti, L.G.; Dajko, M.; Campanella, P.; Shkurti, E.; Ricciardi, W.; de Waure, C. The effect of multifactorial lifestyle interventions on cardiovascular risk factors: A systematic review and meta-analysis of trials conducted in the general population and high risk groups. Prev. Med. 2018, 109, 82–97. [Google Scholar] [CrossRef]
  14. DPP Research Group. Long-term effects of lifestyle intervention or metformin on diabetes development and microvascular complications over 15-year follow-up: The Diabetes Prevention Program Outcomes Study. Lancet Diabetes Endocrinol. 2015, 3, 866–875. [Google Scholar] [CrossRef]
  15. Neamah, H.H.; Sebert Kuhlmann, A.K.; Tabak, R.G. Effectiveness of Program Modification Strategies of the Diabetes Prevention Program: A Systematic Review. Diabetes Educ. 2016, 42, 153–165. [Google Scholar] [CrossRef] [PubMed] [Green Version]
  16. Li, R.; Qu, S.; Zhang, P.; Chattopadhyay, S.K.; Gregg, E.W.; Albright, A.; Hopkins, D.; Pronk, N.P. Economic Evaluation of Combined Diet and Physical Activity Promotion Programs to Prevent Type 2 Diabetes Among Persons at Increased Risk: A Systematic Review for the Community Preventive Services Task Force. Ann. Intern. Med. 2015, 163, 452–460. [Google Scholar] [CrossRef] [PubMed] [Green Version]
  17. Mabry, R.M.; Koohsari, M.J.; Bull, F.; Owen, N. A systematic review of physical activity and sedentary behaviour research in the oil-producing countries of the Arabian Peninsula. BMC Public Health 2016, 16, 1003. [Google Scholar] [CrossRef] [PubMed] [Green Version]
  18. Diabetes Prevention Program Research Group. DPP Lifestyle Materials for Sessions 1–16—Lifestyle Coach Materials and Optional Participant Handouts. Available online: https://dppos.bsc.gwu.edu/web/dppos/lifestyle-handouts (accessed on 2 March 2016).
  19. Panagiotakos, D.B.; Chrysohoou, C.; Pitsavos, C.; Stefanadis, C. Association between the prevalence of obesity and adherence to the Mediterranean diet: The ATTICA study. Nutrition 2006, 22, 449–456. [Google Scholar] [CrossRef]
  20. Hu, F.B.; Rimm, E.B.; Stampfer, M.J.; Ascherio, A.; Spiegelman, D.; Willett, W.C. Prospective study of major dietary patterns and risk of coronary heart disease in men. Am. J. Clin. Nutr. 2000, 72, 912–921. [Google Scholar] [CrossRef] [PubMed]
  21. Stewart, R.A.H.; Wallentin, L.; Benatar, J.; Danchin, N.; Hagström, E.; Held, C.; Husted, S.; Lonn, E.; Stebbins, A.; Chiswell, K.; et al. Dietary patterns and the risk of major adverse cardiovascular events in a global study of high-risk patients with stable coronary heart disease. Eur. Heart J. 2016, 37, 1993–2001. [Google Scholar] [CrossRef] [PubMed]
  22. Holbrook, E.A.; Barreira, T.V.; Kang, M. Validity and reliability of Omron pedometers for prescribed and self-paced walking. Med. Sci. Sports Exerc. 2009, 41, 670–674. [Google Scholar] [CrossRef] [Green Version]
  23. Chiuve, S.E.; Cook, N.R.; Shay, C.M.; Rexrode, K.M.; Albert, C.M.; Manson, J.E.; Willett, W.C.; Rimm, E.B. Lifestyle-based prediction model for the prevention of CVD: The Healthy Heart Score. J. Am. Heart Assoc. 2014, 3, e000954. [Google Scholar] [CrossRef] [Green Version]
  24. Ziegler, A.; Kastner, C.; Blettner, M. The generalised estimating equations: An annotated bibliography. Biom. J. J. Math. Methods Biosci. 1998, 40, 115–139. [Google Scholar] [CrossRef]
  25. Fitzmaurice, G.; Davidian, M.; Verbeke, G.; Molenberghs, G. Longitudinal Data Analysis; Chapman and Hall/CRC: New York, NY, USA, 2009; pp. 45–56. [Google Scholar]
  26. Jaffe, A.; Giveon, S.; Wulffhart, L.; Oberman, B.; Baidousi, M.; Ziv, A.; Kalter-Leibovici, O. Adult Arabs have higher risk for diabetes mellitus than Jews in Israel. PLoS ONE 2017, 12, e0176661. [Google Scholar] [CrossRef] [PubMed]
  27. Kalter-Leibovici, O.; Younis-Zeidan, N.; Atamna, A.; Lubin, F.; Alpert, G.; Chetrit, A.; Novikov, I.; Daoud, N.; Freedman, L.S. Lifestyle intervention in obese Arab women: A randomized controlled trial. Arch. Intern. Med. 2010, 170, 970–976. [Google Scholar] [CrossRef] [PubMed] [Green Version]
  28. Al-Hamdan, R.; Avery, A.; Salter, A.M.; Al-Disi, D.; Al-Daghri, N.M.; McCullough, F. Identification of education models to improve health outcomes in arab women with pre-diabetes. Nutrients 2019, 11, 1113. [Google Scholar] [CrossRef] [PubMed] [Green Version]
  29. Wani, K.; A Alfawaz, H.; Alnaami, A.M.; Sabico, S.; Khattak, M.N.K.; Al-Attas, O.; Alokail, M.S.; Alharbi, M.; Chrousos, G.; Kumar, S. Effects of a 12-month intensive lifestyle monitoring program in predominantly overweight/obese Arab adults with prediabetes. Nutrients 2020, 12, 464. [Google Scholar] [CrossRef] [Green Version]
  30. Sadiya, A.; Abdi, S.; Abusnana, S. Lifestyle Intervention for Weight Loss: A group-based program for Emiratis in Ajman, United Arab Emirates. Diabetes Metab. Syndr. Obesity Targets Ther. 2016, 9, 101–108. [Google Scholar] [CrossRef] [Green Version]
  31. Dunkley, A.J.; Bodicoat, D.H.; Greaves, C.J.; Russell, C.; Yates, T.; Davies, M.J.; Khunti, K. Diabetes prevention in the real world: Effectiveness of pragmatic lifestyle interventions for the prevention of type 2 diabetes and of the impact of adherence to guideline recommendations: A systematic review and meta-analysis. Diabetes Care 2014, 37, 922–933. [Google Scholar] [CrossRef] [Green Version]
  32. Hamman, R.F.; Wing, R.R.; Edelstein, S.L.; Lachin, J.M.; Bray, G.A.; Delahanty, L.; Hoskin, M.; Kriska, A.M.; Mayer-Davis, E.J.; Pi-Sunyer, X.; et al. Effect of weight loss with lifestyle intervention on risk of diabetes. Diabetes Care 2006, 29, 2102–2107. [Google Scholar] [CrossRef] [Green Version]
  33. Afshin, A.; Babalola, D.; McLean, M.; Yu, Z.; Ma, W.; Chen, C.Y.; Arabi, M.; Mozaffarian, D. Information Technology and Lifestyle: A Systematic Evaluation of Internet and Mobile Interventions for Improving Diet, Physical Activity, Obesity, Tobacco, and Alcohol Use. J. Am. Heart Assoc. 2016, 5, e003058. [Google Scholar] [CrossRef] [Green Version]
  34. Franz, M.J.; VanWormer, J.J.; Crain, A.L.; Boucher, J.L.; Histon, T.; Caplan, W.; Bowman, J.D.; Pronk, N.P. Weight-Loss Outcomes: A Systematic Review and Meta-Analysis of Weight-Loss Clinical Trials with a Minimum 1-Year Follow-Up. J. Am. Diet. Assoc. 2007, 107, 1755–1767. [Google Scholar] [CrossRef]
  35. Sidani, S.; Ibrahim, S.; Lok, J.; Fan, L.; Fox, M.; Guruge, S. An integrated strategy for the cultural adaptation of evidence-based interventions. Health 2017, 9, 738. [Google Scholar] [CrossRef] [Green Version]
  36. Kearney, A.; Daykin, A.; Shaw, A.R.G.; Lane, A.J.; Blazeby, J.M.; Clarke, M.; Williamson, P.; Gamble, C. Identifying research priorities for effective retention strategies in clinical trials. Trials 2017, 18, 406. [Google Scholar] [CrossRef] [PubMed]
Figure 1. Flow chart of the study process.
Figure 1. Flow chart of the study process.
Ijerph 17 09184 g001aIjerph 17 09184 g001b
Table 1. Baseline sociodemographic and health characteristics of participants in the quasi-experimental study.
Table 1. Baseline sociodemographic and health characteristics of participants in the quasi-experimental study.
CharacteristicsIntervention (n = 38)Comparison (n = 22)1p-Value
Age, Mean ± SD48.4 ± 12.757 ± 11.30.12
Education level; n (%) 0.08
Elementary school9 (23.7%)10 (45.5%)
High school22 (57.9%)8 (36.4%)
Matriculation exam7 (18.5%)4 (18.6%)
Marital status; n (%) 0.006
Married34 (89.5%)13 (59.1%)
Other4 (10.5%)9 (40.9%)
Parity, Mean (SD)5.3 (2.3)5.4 (2.1)0.923
Employed n (%)6 (16.2%)1 (4.5%)0.24
Self-reported HOD, n (%)
Hypertension4 (11.4%)13 (59.1%)<0.001
Hypercholesterolemia14 (40.0%)13 (59.1%)0.16
Diabetes6 (16.2%)1 (4.5%)0.18
Health behaviors: smoker, n (%)7 (18.9%)5 (22.7%)0.73
BMI categories, n (%) 0.13
Normal6 (15.8%)0
Overweight14 (36.8%)11 (52.4%)
Obese18 (47.4%)10 (47.6%)
SBP, Mean (SD), mmHg129.6 (17.2)126.5 (13.7)0.466
DBP, Mean (SD), mmHg77.2 (9.7)79.9 (11.1)0.333
1p-value for two independent sample t-test if continuous, and χ2 test if categorical. Abbreviations, HOD: history of disease, BMI: body mass index, SBP: systolic blood pressure, DBP: diastolic blood pressure.
Table 2. Generalized Estimating Equations (GEE) regression analysis for differences in outcomes between baseline and six months for the quasi-experiment.
Table 2. Generalized Estimating Equations (GEE) regression analysis for differences in outcomes between baseline and six months for the quasi-experiment.
TimeGroupTime × Group
Dependent VariableWald cBeforeAfterWaldControlInterventionWaldControl BeforeControl AfterIntervention BeforeIntervention After
Average daily portions of:
Vegetables6.11 *1.25 a (0.16)2.01 b (0.26)0.051.60 a (0.22)1.66 a (0.19)2.64 ~1.47 a (0.23)1.58 a (0.41)1.15 a (0.21)2.23 b (0.32)
Fruits6.02 *1.33 a (0.14)2.00 b (0.25)7.73 **2.05 b (0.25)1.28 a (0.15)7.99 **2.09 a (0.28)1.68 a (0.43)0.73 a (0.10)1.92 b (0.27)
Vegetables and fruits6.77 **2.57 a (0.25)3.92 b (0.47)1.843.58 a (0.43)2.91 a (0.30)7.51 **3.56 (0.42)3.14 (0.70)1.86 a (0.26)4.10 b (0.57)
Whole grains0.070.8 (0.13)0.85 (0.14)1.20.7 (0.11)0.93 (0.16)6.2 *0.9 a (0.15)0.4 b (0.08)0.8 a (0.2)1.1 a (0.22)
Average daily Steps21.34 ***4456 a (388)6404 b (557.3)--------
SBP (mmHG)8.80 **128.82 b (2.07)121.71 a (2.23)0.45126.48 a (2.89)124.05 a (2.15)21.17 ***126.5 a (2.86)130.05 a (3.22)129.66 b (2.76)117.06 a (2.48)
DBP (mmHG)4.33 *78.54 a (1.39)73.86 b (2.38)0.5277.27 a (2.81)75.12 a (1.26)0.0679.95 a (2.32)74.28 a (5.71)77.26 a (1.57)73.09 a (1.37)
SBP ≥ 140 (mmHG) c4.39 *0.22 b (0.06)0.09 a (0.06)0.290.16 a (0.08)0.12 a (0.04)1.680.23 a (0.09)0.17 a (0.09)0.21 a (0.07)0.04 a (0.04)
Weight (kg)9.47 **79.66 b (1.96)78.64 a (1.95)0.3080.21 a (2.99)78.08 a (2.50)2.2680.42 a (3.01)80.44 a (2.98)78.74 a (2.52)77.34 a (2.50)
BMI10.18 **31.19 b (0.69)30.78 a (0.68)0.1331.23 a (0.98)30.73 a (0.95)2.1131.32 a (1.00)31.30 a (0.96)30.99 a (0.96)30.44 a (0.95)
Abbreviations, SBP: systolic blood pressure, DBP: diastolic blood pressure, BMI: body mass index. For significant effects, Latin letters show upward ranking, while “a” represents the lowest estimate and “b” represents the highest estimate. These estimations were based on a post-hoc pairwise comparison with Bonferroni correction. “~” stands for rejection criterion at p < 0.10. c For dichotomous dependent variables, the marginal means are estimated probabilities. p-value: *** p < 0.001, ** p < 0.01, * p < 0.05. Cronbach’s Alpha: 0.95.
Table 3. Baseline sociodemographic and health characteristics of participants in the dissemination phase.
Table 3. Baseline sociodemographic and health characteristics of participants in the dissemination phase.
Variablen = 117
Age group n (%)
<4544 (37.9%)
45–5954 (46.6%)
60+18 (15.5%)
Education level: n (%)
Elementary school14 (12.1%)
High school53 (45.7%)
Vocational training27 (23.3%)
Academic degree22 (19%)
Marital status; n (%)
Married92 (79.3%)
Other24 (20.7%)
Parity, Mean (SD)4.18 (2.3%)
Participant’s employment
Yes8 (7%)
No107 (93%)
Spouse employed77 (81.1%)
Self-reported HOD, n (%)
Hypertension20 (17.1%)
Heart attack3 (2.6%)
Hypercholesterolemia39 (33.3%)
Diabetes22 (18.8%)
Weight, Mean (SD), kg77.9 (16.0%)
BMI categories: n (%)
Normal18 (5.5%)
Overweight39 (33.6%)
Obese58 (50%)
SBP, Mean (SD), mmHg128.6 (20%)
DBP, Mean (SD), mmHg81 (14.8%)
Abbreviations, HOD: history of disease, BMI: body mass index. SBP: systolic blood pressure, DBP: diastolic blood pressure.
Table 4. GEE regression analysis for differences in outcomes between baselines, six months, and 6 months following the program completion for the dissemination phase.
Table 4. GEE regression analysis for differences in outcomes between baselines, six months, and 6 months following the program completion for the dissemination phase.
Dependent VariableWald Chi-SquareMarginal Means
TimeGroupTime × GroupTime 1Time 2Time 3Total
Average daily portions of:
Vegetables12.01 **11.06 **11.01 *1.76 a (0.11)2.32 b (0.13)2.09 b (0.14)2.06 (0.08)
Fruit0.624.575.021.81 (0.12)1.91 (0.09)1.89 (0.12)1.87 (0.08)
Vegetables & Fruit7.30 *9.63 **6.203.60 a (0.20)4.25 b (0.18)3.99 a b (0.22)3.95 (0.14)
Achieving the recommended ≥ 5 per day10.88 **1.812.580.25 a (0.04)0.43 b (0.05)0.44 b (0.06)0.37 (0.03)
Whole grains1.3331.4 ***11.97 *1.23 (0.12)1.38(0.10)1.32 (0.10)1.31 (0.07)
Sweetened drinks2.666.41 *22.46 ***2.660.65 (0.12)0.85 (0.17)0.54 (0.10)
Sweets9.48 **1.2017.82 **9.48 **1.48 a (0.13)1.03 b (0.11)1.20 (0.14)
Olive oil (tbl per week)0.415.59 *7.71 *4.68 (0.33)4.77 (0.43)4.98 (0.47)4.81 (0.29)
Average daily steps (ADS)63.69 ***14.99 **1.364087.4 a (188.6)5284.2 b (234.4)-4647.4 (196.6)
Participants increased their ADS > 450026.70 ***8.70 *0.500.36 a (0.05)0.64 b (0.05)-0.50 (0.05)
PA moderate intensity22.78 ***1.754.9297.82 a (13.21)191.32 b (19.97)183.95 b (28.40)151.00 (13.68)
PA vigorous intensity12.10 **4.0215.36 **99.12 a (16.16)155.72 b (24.50)99.92 a (22.28)104.59 (15.27)
Achieving the recommended PA > 150 min/week24.17 ***0.048.070.33 a (0.05)0.64 b (0.05)0.53 b (0.6)0.50 (0.04)
SBP22.54 ***3.4010.84 *128.15 b (1.88)121.34 a (1.66)119.01 a (2.12)122.77 (1.44)
DBS11.52 **3.562.2480.80 b (1.40)77.03 a (0.95)75.46 a (1.69)77.73 (1.00)
SBP ≥ 1407.66 *0.856.490.27 b (0.04)0.19 b (0.04)0.08 a (0.05)0.16 (0.04)
Weight1.101.0510.20 *77.52 (1.45)76.88 (1.41)76.81 (1.42)77.07 (1.38)
BMI1.640.1811.60 *30.41 (0.52)30.11 (0.50)30.18 (0.52)30.24 (0.50)
HbA1C3.253.032.295.71 (0.10)5.67 (0.08)5.34 (0.22)5.57 (0.09)
Total cholesterol mg/dL7.91 **0.510.80187.07 b (3.05)176.33 a (3.81)-181.62 (2.91)
HDL-mg/dL2.585.401.3651.30 (1.49)47.98 (1.66)-49.61 (1.20)
LDL-mg/dL7.49 **2.471.36111.55 b (2.84)97.58 a (4.22)-104.33 (2.68)
TG-mg/dL0.450.549.09 *123.20 (5.97)118.36 (7.76)-12.75 (5.94)
Abbreviations, tbl: table spoon, PA: physical activity, SBP: systolic blood pressure, DBP: diastolic blood pressure, BMI: body mass index, glycated hemoglobin A1C. For significant effects, Latin letters show upward ranking, while “a” represents the lowest estimate and “b” represents the highest estimate. “a b” indicates no change in the estimate at Time 3. These estimations were based on a post-hoc pairwise comparison with Bonferroni correction. For dichotomous dependent variables, the marginal means are estimated probabilities. p–value: *** p < 0.001, ** p < 0.01, * p < 0.05. Cronbach’s Alpha: 0.95.
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Agbaria, N.; Nubani-Husseini, M.; Barakat, R.A.; Leiter, E.; Greenberg, K.L.; Karjawally, M.; Keidar, O.; Donchin, M.; Zwas, D.R. Two-Phase Evaluation of a Community-Based Lifestyle Intervention for Palestinian Women in East Jerusalem: A Quasi-Experimental Study Followed by Dissemination. Int. J. Environ. Res. Public Health 2020, 17, 9184. https://doi.org/10.3390/ijerph17249184

AMA Style

Agbaria N, Nubani-Husseini M, Barakat RA, Leiter E, Greenberg KL, Karjawally M, Keidar O, Donchin M, Zwas DR. Two-Phase Evaluation of a Community-Based Lifestyle Intervention for Palestinian Women in East Jerusalem: A Quasi-Experimental Study Followed by Dissemination. International Journal of Environmental Research and Public Health. 2020; 17(24):9184. https://doi.org/10.3390/ijerph17249184

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Agbaria, Nisreen, Maha Nubani-Husseini, Raghda A. Barakat, Elisheva Leiter, Keren L. Greenberg, Mayada Karjawally, Osnat Keidar, Milka Donchin, and Donna R. Zwas. 2020. "Two-Phase Evaluation of a Community-Based Lifestyle Intervention for Palestinian Women in East Jerusalem: A Quasi-Experimental Study Followed by Dissemination" International Journal of Environmental Research and Public Health 17, no. 24: 9184. https://doi.org/10.3390/ijerph17249184

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