Impaired Odor Identification of Culturally Familiar Odorants Associated with Dementia in South Korean Older Adults
Abstract
:1. Introduction
2. Materials and Methods
2.1. Study Participants
2.2. Measurement
2.2.1. Neurocognitive Test
2.2.2. YSK Olfactory Function Test
2.2.3. Statistical Analysis
3. Results
3.1. Sociodemographic and Clinical Characteristics of the Study Population
3.2. Results of the Hierarchical Linear Regression Analysis
3.3. Results of the Hierarchical Logistic Regression Analysis
4. Discussion
5. Conclusions
Author Contributions
Funding
Conflicts of Interest
References
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Normal Cognition (n = 99) | Dementia (n = 40) | Statistics | p-Value | |
---|---|---|---|---|
t/χ2 | ||||
Age | 68.48 ± 5.07 | 74.15 ± 5.55 | t = −5.801 | <0.001 |
Sex (male/female) | 25/74 (25.3%/74.7%) | 14/26 (35.0%/65.0%) | t = 1.341 | 0.247 |
Education | χ2 = 2.956 | 0.086 | ||
Below middle school | 51 (51.5%) | 27 (67.5%) | ||
High school graduate or higher | 48 (48.5%) | 13 (32.5%) | ||
CERAD-K score | 74.18 ± 10.41 | 26.60 ± 13.58 | t = 19.920 | <0.001 |
YSK Odor identification score | 10.05 ± 2.66 | 5.28 ± 3.37 | t = 8.004 | <0.001 |
Independent Variables | Model 1 | Model 2 | |||||||
---|---|---|---|---|---|---|---|---|---|
B | Beta | t | p-Value | B | Beta | t | p-Value | ||
Demographic factors | Sex (female) | −1.071 | −0.020 | −0.274 | 0.785 | −5.624 | −0.104 | −1.661 | 0.099 |
Age, years | −2.164 | −0.514 | −7.180 | <0.001 | −1.164 | −0.276 | −3.996 | <0.001 | |
Level of education (low) | −11.017 | −0.225 | −3.120 | 0.002 | −6.921 | −0.141 | −2.264 | 0.025 | |
Odor identification function | YSK Odor identification score | 3.486 | 0.514 | 7.246 | <0.001 | ||||
Statistics of the model | F = 23.590 ***, R2 = 0.344 | F = 37.567 ***, R2 = 0.529, F Change = 52.502 ***, R2 Change = 0.185 |
Independent Variables | Model 1 | Model 2 | |||||||
---|---|---|---|---|---|---|---|---|---|
B | Wald | p-Value | OR | B | Wald | p-Value | OR | ||
Demographic factors | Sex (female) | −0.248 | 0.277 | 0.599 | 0.780 | 0.492 | 0.522 | 0.470 | 1.635 |
Age, years | 0.219 | 20.391 | 0.000 | 1.245 | 0.162 | 7.918 | 0.005 | 1.176 | |
Level of education (low) | 0.557 | 1.559 | 0.212 | 1.746 | −0.160 | 0.056 | 0.813 | 0.852 | |
Odor identification (OI) (false for all items) | Item 1: baby powder | 0.029 | 0.002 | 0.966 | 1.029 | ||||
Item 2: cinnamon | 0.054 | 0.006 | 0.938 | 1.055 | |||||
Item 3: peaches | 0.610 | 0.732 | 0.392 | 1.840 | |||||
Item 4: crust of overcooked rice | 0.670 | 0.865 | 0.352 | 1.953 | |||||
Item 5: spearmint | 0.770 | 1.210 | 0.271 | 2.160 | |||||
Item 6: chocolate | −1.623 | 3.175 | 0.075 | 0.197 | |||||
Item 7: herbal medicine | 2.243 | 6.339 | 0.012 | 9.420 | |||||
Item 8: medicated patch | 0.091 | 0.014 | 0.906 | 1.095 | |||||
Item 9: red ginseng | 0.561 | 0.462 | 0.497 | 1.753 | |||||
Item 10: naphthalene | −1.446 | 3.580 | 0.058 | 0.236 | |||||
Item 11: Korean grilled meat | 1.679 | 5.502 | 0.019 | 5.361 | |||||
Item 12: ash | 1.171 | 2.225 | 0.136 | 3.226 | |||||
Statistics of the model | −2LL | 133.378 | 93.663 | ||||||
Step χ2 | 33.462 *** (df = 3) | 39.717 *** (df = 12) | |||||||
Model χ2 | 33.462 *** (df = 3) | 73.179 *** (df = 15) | |||||||
Nagelkerke R2 | 0.306 | 0.586 | |||||||
Classification accuracy | 77.7% | 88.5% |
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Kim, S.M.; Kim, H.R.; Min, H.J.; Kim, K.S.; Ga, H.; Lee, S.H.; Han, D.H. Impaired Odor Identification of Culturally Familiar Odorants Associated with Dementia in South Korean Older Adults. Int. J. Environ. Res. Public Health 2020, 17, 8441. https://doi.org/10.3390/ijerph17228441
Kim SM, Kim HR, Min HJ, Kim KS, Ga H, Lee SH, Han DH. Impaired Odor Identification of Culturally Familiar Odorants Associated with Dementia in South Korean Older Adults. International Journal of Environmental Research and Public Health. 2020; 17(22):8441. https://doi.org/10.3390/ijerph17228441
Chicago/Turabian StyleKim, Sun Mi, Hye Ri Kim, Hyun Jin Min, Kyung Soo Kim, Hyuk Ga, Sang Hoon Lee, and Doug Hyun Han. 2020. "Impaired Odor Identification of Culturally Familiar Odorants Associated with Dementia in South Korean Older Adults" International Journal of Environmental Research and Public Health 17, no. 22: 8441. https://doi.org/10.3390/ijerph17228441