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The Most Effective Amount of Forward Movement for Oral Appliances for Obstructive Sleep Apnea: A Systematic Review
Open AccessArticle

Japanese Cross-Sectional Multicenter Survey (JAMS) of Oral Appliance Therapy in the Management of Obstructive Sleep Apnea

Department of Geriatric Dentistry, Osaka Dental University, Osaka-city 540-0008, Japan
Division for Oral and Facial Disorders, Osaka University Dental Hospital, Suita-city 565-0871, Japan
Department of Oral and Maxillofacial Surgery, Aichi Medical University, Nagakute-city 480-1195, Japan
Dental Clinic for Sleep Disorders (Apnea and Snoring), Oral and Maxillofacial Rehabilitation, University Hospital of Dentistry, Tokyo Medical and Dental University, Tokyo 113-8510, Japan
Division of Oral Function and Rehabilitation, Department of Oral Health Science, Nihon University School of Dentistry at Matsudo, Matsudo-city 271-0061, Japan
Ota Memorial Sleep Center, Sleep Surgery Center, Kawasaki-city 210-0024, Japan
Dentistry and Oral Surgery, JR Tokyo General Hospital, Tokyo 151-8528, Japan
Department of Dentistry and Maxillo-Facial Surgery, Komatsu Hospital, Neyagawa-city 572-0015, Japan
Katahira Dental Clinic, Tokyo 151-0053, Japan
Furuhata Sleep-disordered Breathing Research Institute, Furuhata Dental Clinic, Tokyo 107-0052, Japan
Snore & Sleep Apnea Treatment Center, Nippon Dental University Hospital Internal Medicine, Tokyo 173-8610, Japan
Iida Dental Clinic, Soka-city 340-0013, Japan
Author to whom correspondence should be addressed.
Int. J. Environ. Res. Public Health 2019, 16(18), 3288;
Received: 5 August 2019 / Revised: 3 September 2019 / Accepted: 5 September 2019 / Published: 6 September 2019
(This article belongs to the Special Issue Sleep Apnea Syndrome)
We conducted a multicenter survey for oral appliance (OA) therapy to grasp and analyze the current situation of OA therapy, including efficacy, side effects, and follow-up, in Japan. The Japanese cross-sectional multicenter survey (JAMS) for obstructive sleep apnea (OSA) was undertaken by patients in 10 institutions associated with oral appliance therapy during two years, from 2014 to 2015, retrospectively. Age, sex, body mass index (BMI), baseline apnea–hypopnea index (AHI), OA type, adjustment, adverse reactions with OA, and AHI with OA were elicited from the patient clinical record. The number of included OSA patients was 3217. The number of patients with OA therapy was 2947. We evaluated 1600 patients for the OA treatment. The patients treated with OA, both male and female, were most commonly in their 50s. In terms of OSA severity, snoring was 2.3%, mild was 38.5%, moderate was 39.9%, and severe was 19.3%. The use of mono bloc appliance was 91.8%, bi bloc appliance was 7.9%, and tongue-retaining device (TRD) was 0.3%. After OA treatment, AHI decreased from 22.4/h to 9.3/h. The AHI reduction rate with OA was 52.0%. The rate of AHI <5 with OA was 35.6%. Adverse reactions developed in 14.7% of the subjects. OA reassessment was conducted for 54.3%. This study revealed the current situation of efficacy and side effects of OA therapy, and the problem that the reassessment rate of OA was low in Japan. View Full-Text
Keywords: obstructive sleep apnea (OSA); oral appliance (OA); multicenter survey obstructive sleep apnea (OSA); oral appliance (OA); multicenter survey
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Okuno, K.; Furuhashi, A.; Nakamura, S.; Suzuki, H.; Arisaka, T.; Taga, H.; Tamura, M.; Katahira, H.; Furuhata, M.; Iida, C. Japanese Cross-Sectional Multicenter Survey (JAMS) of Oral Appliance Therapy in the Management of Obstructive Sleep Apnea. Int. J. Environ. Res. Public Health 2019, 16, 3288.

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