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Open AccessArticle

Study of Factors Influencing the Bioaccessibility of Triazolone in Cherry Tomatoes Using a Static SHIME Model

1
School of Resource & Environment, Anhui Agricultural University, Hefei 230036, China
2
Provincial Key Laboratory for Agri-Food Safety, Anhui Agricultural University, Hefei 230036, China
3
School of Plant Protection, Anhui Agricultural University, Hefei 230036, China
*
Author to whom correspondence should be addressed.
These authors contributed equally to this work.
Int. J. Environ. Res. Public Health 2018, 15(5), 993; https://doi.org/10.3390/ijerph15050993
Received: 14 April 2018 / Revised: 5 May 2018 / Accepted: 9 May 2018 / Published: 15 May 2018
(This article belongs to the Section Environmental Health)
Estimating the influence of bioaccessibility of pesticide residues in fruits and vegetables on dietary exposure is a challenge for human health risk assessment. This study investigated the bioaccessibility of pesticide residues in cherry tomatoes and contributing factors (digestion time, pH, solid/liquid ratio, and dietary nutrition) using an in vitro test simulating the human gastrointestinal tract. pH had the largest effect on triazolone precipitation in the simulated gastric intestinal juice, which had a significant impact on the bioaccessibility. The bioaccessibility of triazolone in the intestinal stage was slightly higher than that in the stomach stage, owing to bile salts and pancreatic enzymes present in the intestinal juice. The bioaccessibility of triazolone did not change significantly with digestion time. In the gastric stage, there was a logarithmic relationship between the bioaccessibility and solid/liquid ratio (R2 = 0.9941). The addition of oil significantly changed the bioaccessibility in the gastrointestinal stage. Protein and dietary fiber only affected bioaccessibility in the stomach stage. Dietary nutrition can reduce the release of pesticides from fruits and vegetables into the stomach, sharply reducing the bioaccessibility, and the dietary exposure of pesticide residues in fruits and vegetables can be properly evaluated. View Full-Text
Keywords: bioaccessibility; triazolone; cherry tomatoes; Simulator of the Human Intestinal Microbial Ecosystem (SHIME); risk assessment bioaccessibility; triazolone; cherry tomatoes; Simulator of the Human Intestinal Microbial Ecosystem (SHIME); risk assessment
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MDPI and ACS Style

Liu, Y.-Y.; Xiao, J.-J.; Fu, Y.-Y.; Liao, M.; Cao, H.-Q.; Shi, Y.-H. Study of Factors Influencing the Bioaccessibility of Triazolone in Cherry Tomatoes Using a Static SHIME Model. Int. J. Environ. Res. Public Health 2018, 15, 993.

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