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Open AccessArticle

Analysis of the Content of Chromium in Certain Parts of the Human Knee Joint

The Jan Grodek Higher Vocational State School, Medical Institute, 21 Mickiewicza Str., 38-500 Sanok, Poland
Department of Toxicology and Bioanalysis, School of Pharmacy with the Division of Laboratory Medicine, Medical University of Silesia, 4 Jagiellonska Str., 41-200 Sosnowiec, Poland
Department of Inorganic, Analytical Chemistry and Electrochemistry, Faculty of Chemistry, Silesian University of Technology, 6 B. Krzywoustego Str., 44-100 Gliwice, Poland
Author to whom correspondence should be addressed.
Int. J. Environ. Res. Public Health 2018, 15(5), 1013;
Received: 7 April 2018 / Revised: 13 May 2018 / Accepted: 14 May 2018 / Published: 17 May 2018
Chromium is an essential microelement in the human body. It exerts an effect on bones by modulating their biochemical parameters: alkaline phosphatase (ALP) and tartrate-resistant acid phosphatase (TRAP). With considerable accumulation of chromium in the skeleton, the activity of alkaline phosphatase was found to decrease, which affected bone formation rate. The study objective was to analyze chromium content in the knee tissues. Tissues for analysis were obtained during endoprosthesoplasty of the knee joint and included tibia, femur, and meniscus tissues. Samples were collected from 50 patients, including 36 women and 14 men. The analysis was performed using the inductively coupled plasma atomic emission spectroscopy (ICP-AES) method, by means of a Varian 710-ES apparatus. The results revealed no significant differences in the content of chromium in the knee joint tissues between women and men. The highest level of chromium was found in the femoral bone of the knee joint, then in the meniscus, and was lowest in the tibia, although the differences were statistically insignificant. Chromium content increased with age. View Full-Text
Keywords: knee joint tissues; chromium knee joint tissues; chromium
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Roczniak, W.; Brodziak-Dopierała, B.; Cipora, E.; Jakóbik-Kolon, A.; Konieczny, M.; Babuśka-Roczniak, M. Analysis of the Content of Chromium in Certain Parts of the Human Knee Joint. Int. J. Environ. Res. Public Health 2018, 15, 1013.

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