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Open AccessArticle

Cardiovascular System Response to Carbon Dioxide and Exercise in Oxygen-Enriched Environment at 3800 m

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School of Aeronautic Science and Engineering, Beihang University, Beijing 100191, China
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High Altitude Physiology Laboratory, Institute of Aviation Medicine, Air Force, Beijing 100142, China
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Authors to whom correspondence should be addressed.
Academic Editor: Paul B. Tchounwou
Int. J. Environ. Res. Public Health 2015, 12(9), 11781-11796; https://doi.org/10.3390/ijerph120911781
Received: 27 May 2015 / Revised: 5 August 2015 / Accepted: 6 August 2015 / Published: 18 September 2015
Background: This study explores the responses of the cardiovascular system as humans exercise in an oxygen-enriched room at high altitude under various concentrations of CO2. Methods: The study utilized a hypobaric chamber set to the following specifications: 3800 m altitude with 25% O2 and different CO2 concentrations of 0.5% (C1), 3.0% (C2) and 5.0% (C3). Subjects exercised for 3 min three times, separated by 30 min resting periods in the above-mentioned conditions, at sea level (SL) and at 3800 m altitude (HA). The changes of heart rate variability, heart rate and blood pressure were analyzed. Results: Total power (TP) and high frequency power (HF) decreased notably during post-exercise at HA. HF increased prominently earlier the post-exercise period at 3800 m altitude with 25% O2 and 5.0% CO2 (C3), while low frequency power (LF) changed barely in all tests. The ratios of LF/HF were significantly higher during post-exercise in HA, and lower after high intensity exercise in C3. Heart rate and systolic blood pressure increased significantly in HA and C3. Conclusions: Parasympathetic activity dominated in cardiac autonomic modulation, and heart rate and blood pressure increased significantly after high intensity exercise in C3. View Full-Text
Keywords: heart rate variability; heart rate; blood pressure; cardiac autonomic modulation; exercise heart rate variability; heart rate; blood pressure; cardiac autonomic modulation; exercise
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Liu, G.; Liu, X.; Qin, Z.; Gu, Z.; Wang, G.; Shi, W.; Wen, D.; Yu, L.; Luo, Y.; Xiao, H. Cardiovascular System Response to Carbon Dioxide and Exercise in Oxygen-Enriched Environment at 3800 m. Int. J. Environ. Res. Public Health 2015, 12, 11781-11796.

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