Order Astrophorida Family Ancorinidae | Sponge | Symbiont | Compound | Property | Reference |
|
Stelletta tenuis (South China Sea) | Alcaligenes faecalis A72 (β-Proteobacteria) | Cyclo-(L-Pro-L-Phe) | Antimicrobial | [42] |
Jaspis aff. johnstoni (Indo-Pacific) | Hyphomycete fungus (Deuteromycota (fungus)) | Chloriolin B | Antitumor | [43–45] |
|
Order Chondrosida Family Chondrillidae | Chondrosia reniformis (Elba, Italy) | Penicillium rugulosum (Ascomycota (fungus)) | Prugosene A1 | Anti-infective | [46–48] |
Prugosene A2 | Anti-infective | [46–48] |
Prugosene A3 | Anti-infective | [46–48] |
Prugosene B1 | Anti-infective | [46–48] |
Prugosene B2 | Anti-infective | [46–48] |
Prugosene C1 | Anti-infective | [46–48] |
Prugosene C2 | Anti-infective | [46–48] |
|
Order Dendroceratida Family Darwinellidae | Dendrilla nigra (Vizhinjam, India) | Streptomyces dendra sp. nov. MSI051 (Actinobacteria) | Unidentified compound | Antibacterial | [51] |
|
Dendrilla nigra (Kanyakumari, India) | Streptomyces sp. BLT7 (Actinobacteria) | Unidentified compound | Antibacterial | [52,53] |
|
Dendrilla nigra (South east coast, India) | Nocardiopsis dassonvillei MAD08 (Actinobacteria) | Acetic acid,-butyl-ester | Antimicrobial | [53] |
Ethanol, 2-(octyloxy)- | Antimicrobial | [53] |
Oxalic acid, allyl-nonyl ester | Antimicrobial | [54] |
2-Isopropyl-5-methyl-1-heptanol | Antimicrobial | [53] |
Butylated-hydroxytoluene | Antimicrobial | [53] |
Cyclohexane-carboxylic acid, hexyl ester | Antimicrobial | [53] |
Diethyl-phthalate | Antimicrobial | [53] |
Pentadecanal- | Antimicrobial | [53] |
1-Tridecanol | Antimicrobial | [53] |
9-Octadecenal | Antimicrobial | [53] |
Hexadecanoic acid, methyl-ester | Antioxidant, hypo-cholesterolemic, nematicide, antiandrogenic, hemolytic | [53] |
n-Hexadecanoic-acid | Antioxidant, hypo-cholesterolemic, nematicide, antiandrogenic, hemolytic | [53] |
Hexadecanoic-acid, ethyl ester | Antioxidant, hypo-cholesterolemic, nematicide, antiandrogenic, hemolytic | [53] |
9-Octadecenoic-acid-(Z)-, methyl-ester | Anti-inflammatory, antiandrogenic, cancer-preventive, dermatitigenic, hypo-cholesterolemic, anemiagenic | [53] |
Oleic Acid | Anti-inflammatory, antiandrogenic, cancer-preventive, dermatitigenic, hypo-cholesterolemic, anemiagenic | [53] |
(E)-9-Octadecenoic-acid ethyl ester | Anti-inflammatory, antiandrogenic, cancer-preventive, dermatitigenic, hypo-cholesterolemic, anemiagenic | [53] |
9-Octa-decenamide-(Z)- | Anti-inflammatory, antiandrogenic, cancer-preventive, dermatitigenic, hypo-cholesterolemic, anemiagenic | [53] |
|
Order Dictyoceratida Family Dysideidae | Lamellodysidea herbacea (Great Barrier Reef, Australia) | Oscillatoria spongeliae (Cyanobacteria) | Dihydrodysamide C | Therapeutic (unknown action) | [57] |
Didechloro-dihydrodysamide C | Therapeutic (unknown action) | [57] |
|
Dysidea sp. (Eastern Samoa) | Vibrio sp. (γ-Proteobacteria) | Tetrabromo-diphenyl ethers | Cytotoxic, antibacterial | [59] |
|
Lamellodysidea herbacea (Republic of Palau) | Oscillatoria spongeliae (Cyanobacteria) | 2-(2′,4′-dibromo-phenyl)-4,6-dibromophenol | Anibacterial | [40] |
|
Dysidea avara (Adriatic Sea) | Unidentified bacterium | 2-methylthio-1,4-naphthoquinone | Antiangiogenic, antimicrobial | [61,62] |
|
Irciniidae | Ircinia fasciculata (Mediterranean Sea) | Penicillium chrysogenum (Ascomycota (fungus)) | Sorbicillactone A | Antileukemic, anti HIV | [64,65] |
|
Spongiidae | Hyatella sp. | Vibrio sp. M22-1 (γ-Proteobacteria) | Andrimid | Antibiotic | [66] |
|
| Spongia sp. (Hawaii) | Myrothecium verrucaria 973023 (Deuteromycota (fungus)) | 3-hydroxyroridin E | Antileukemic, antitumor | [69] |
13′-acetyl-trichoverrin B | Antileukemic, antitumor | [69] |
Roridin A | Antileukemic, antitumor | [69] |
Roridin L | Antileukemic, Antitumor | [69] |
Roridin M | Antileukemic, Antitumor | [69] |
Verrucarin M | Antileukemic, antitumor | [69] |
Verrucarin A | Antileukemic, antitumor | [69] |
Isororidin A | Antileukemic, antitumor | [69] |
Epiroridin E | Antileukemic, antitumor | [69] |
Trichoverrin A | Antileukemic, antitumor | [69] |
Trichoverrin B | Antileukemic, antitumor | [69] |
|
Thorectidae | Hyrtios altum (Okinawa) | Vibrio sp. (γ-Proteobacteria) | Trisindoline | Antibiotic | [70–72] |
|
Hyrtios sp. (Caribbean Sea) | Aspergillus niger (Ascomycota (fungus)) | Asperazine | Antileukemic, cytotoxic | [45,74,75] |
|
Hyrtios proteus (Dry Tortugas National Park, Florida ) | Aspergillus niger (Ascomycota (fungus)) | Asperazine | Antileukemic, cytotoxic | [76] |
Malformin C | Antitumor | [76] |
Fascaplysinopsis reticulate (Great Barrier Reef, Australia) | Pseudo-alteromonas maricaloris KMM 636T (γ-Proteobacteria) | Bromo-alterochromide A | Cytotoxic | [48,76] |
|
| Bromo-alterochromide A | Cytotoxic | [48,76] |
|
Order Hadromerida Family Spirastrellidae | Spirastrella vagabunda (Indonesia) | Unidentified fungus | 14,15-secocurvularin | Antibiotic | [77,78] |
|
Suberitidae | Suberites domuncula (Northern Adriatic Sea) | α-Proteobacterium MBIC3368 (isolate 1) | Unidentified compound | Antiangiogenic, antimicrobial, hemolytic, cytotoxic | [15,79] |
α-Proteobacterium MBIC3368 (isolate 2) | Unidentified compound | Antimicrobial, hemolytic | [15,80] |
Idiomarina sp. (γ-Proteobacteria) | Unidentified compound | Hemolytic | [15,80] |
Pseudomonas sp. (isolate 1) (γ-Proteobacteria) | Unidentified compound | Hemolytic, cytotoxic | [15,80] |
Pseudomonas sp. (isolate 2) (γ-Proteobacteria) | Unidentified compound | Antiangiogenic, antimicrobial, hemolytic, cytotoxic | [15,80] |
|
Order Halichondrida Family Axinellidae | Ptilocaulis trachys (Enewetak Atoll, Marshall Island, Pacific Ocean) | Lyngbya majuscula (Cyanobacteria) | Majusculamide C | Antifungal | [81,82] |
|
Axinella sp. (South China Sea) | Myrothecium sp. JS9 (Deuteromycota (fungus)) | Roridin A | Antifungal | [83] |
Roridin D | Antifungal | [83] |
|
Axinella sp. (Papaua New Guinea) | Penicillium citrinum (Ascomycota (fungus)) | Isocyclocitrinol A | Antibacterial | [84] |
22-acetyl-isocyclocitrinol A | Antibacterial | [84] |
|
Axinella verrucosa (Mediterranean Sea) | Penicillium sp. (Ascomycota (fungus)) | Oxaline | Anti-proliferative | [85] |
Griseofulvin | Antifungal | [85,86] |
Communesin B | Antileukemic | [85,87] |
Communesin C | Antileukemic | [85,87] |
Communesin D | Antileukemic | [85,87] |
|
Axinella sp. (Papua New Guinea) | Acremonium sp. (Ascomycota (fungus)) | Efrapeptin E | Cytotoxic, antibacterial | [90] |
Efrapeptin F | Cytotoxic, antibacterial | [90] |
Efrapeptin Eα | Cytotoxic, antibacterial | [90] |
Efrapeptin G | Cytotoxic, antibacterial | [89] |
Efrapeptin H | Cytotoxic, antibacterial | [90] |
RHM1 | Antibacterial | [89] |
|
Axinella damicornis (Mediterranean Sea) | Aspergillus niger (Ascomycota (fungus)) | Bicoumanigrin | Anticancer, cytotoxic | [88] |
Aspernigrin B | Neuroprotective | [88] |
|
Halichondriidae | Halichondria okadai | Alteromonas sp. (γ-Proteobacteria) | Alteramide A | Anticancer, cytotoxic | [93–95] |
|
Halichondria okadai (Japan) | Trichoderma harzianum OUPS-N115 (Ascomycota (fungus)) | Trichodenone A | Antileukemic, cytotoxic | [78,96,97] |
Trichodenone B | Antileukemic, cytotoxic | [78,96,97] |
Trichodenone C | Antileukemic, cytotoxic | [78,96,97] |
|
Halichondria okadai | Rubritalea squalenifasciens HOact23T (Verrucomicrobiae) | Dia-polycopenedioic acid xylosyl esters A | Antioxidant | [30,48,98] |
Dia-polycopenedioic acid xylosyl esters B | Antioxidant | [30,48,98] |
Dia-polycopenedioic acid xylosyl esters C | Antioxidant | [30,48,98] |
|
Halichondria panacea | Unidentified bacterium | Unidentified compound | Neuroactive | [100] |
|
Halichondria panacea (Adriatic coast, Croatia) | Microbacterium sp. (Actinobacteria) | 1-O-acyl-3-[R-glucopyranosyl-(1–3)-(6-O-acyl-R-manno-pyranosyl)]-glycerol | Antitumor | [101] |
|
Halichondria japonica (Osaka Bay, Japan) | Gymnascella dankaliensis OUPS-N134 (Ascomycota (fungus)) | Gymnostatin A | Antileukemic, cytotoxic | [78,102,103,105] |
Gymnostatin B | Antileukemic, cytotoxic | [78,102,103,105] |
Gymnostatin C | Antileukemic, cytotoxic | [78,102,103,105] |
Gymnostatin F | Antileukemic, cytotoxic | [106] |
Gymnostatin G | Antileukemic, cytotoxic | [106] |
Gymnostatin Q | Antileukemic, anti cancer, cytotoxic | [107] |
Gymnostatin R | Antileukemic, cytotoxic | [107] |
Gymnasterone A | Cytotoxic | [108,109] |
Gymnasterone B | Antileukemic, cytotoxic | [108,109] |
Gymnasterone C | Antileukemic, cytotoxic | [108] |
Gymnasterone D | Antileukemic, cytotoxic | [108] |
Dankastatin A | Antileukemic, cytotoxic | [107] |
Dankastatin B | Antileukemic, cytotoxic | [107] |
Dankasterone A | Antileukemic, anticancer, cytotoxic | [104] |
|
Halichondria Japonica (Japan) | Phoma sp. Q60596 (Ascomycota (fungus)) | YM-202204 | Antifungal | [110] |
|
Halichondria Japonica | Bacillus cereus QN03323 (Firmicutes) | YM-266183 | Antibacterial | [111–113] |
YM-266184 | Antibacterial | [111–113] |
|
Acanthella acuta (Mediterranean Sea) | Bacillus pumilus AAS3 (Firmicutes) | GG11 | Antitumor | [116] |
|
Hymeniacidon perlevis (Nanji Island, China Sea) | Pseudo-alteromonas piscicida NJ6-3-1 (γ-Proteobacteria) | Norharman | Antimicrobial | [43,117] |
|
Hymeniacidon perlevis (Fujiazhuang coast, China) | Fusarium oxysporum DLFP2008005 (Ascomycota (fungus)) | Unidentified compound | Antibacterial, antifungal | [44] |
|
Order Haplosclerida Family Callyspongiidae | Callyspongia aerizusa (Indonesia) | Cladosporium herbarum (Deuteromycota (fungus)) | Sumiki’s acid | Antibacterial | [118] |
Acetyl Sumiki’s acid | Antibacterial | [118] |
|
Callyspongia vaginalis (Caribbean Sea) | Ulocladium botrylis 193A4 (Ascomycota (fungus)) | Ulocladol | Antimicrobial | [119,120] |
1-hydroxy-6-methyl-8-(hydroxylmethyl)-xanthone | Antifungal | [119,120] |
|
Chalinidae | Haliclona valliculata (Elba, Italy) | Emericella variecolor (Ascomycota (fungus)) | Evariquinone | Anti-proliferative | [122] |
|
Haliclona simulans (Ireland) | Pseudo-alteromonas sp. PA2 (γ-Proteobacteria) | Unidentified | Antimicrobial | [123] |
Pseudo-alteromonas sp. PA4 (γ-Proteobacteria) | Unidentified | Antimicrobial | [123] |
Pseudo-alteromonas sp. PA5 (γ-Proteobacteria) | Unidentified | Antimicrobial | [123] |
Pseudo-alteromonas sp. PA5 (γ-Proteobacteria) | Unidentified | Antimicrobial | [123] |
Halomonas sp. HM4 ( γ-Proteobacteria) | Unidentified | Antimicrobial | [123] |
Psychrobacter sp. PB1 (γ-Proteobacteria) | Unidentified | Antimicrobial | [123] |
Marinobacter sp. MB1 (γ-Proteobacteria) | Unidentified | Antimicrobial | [123] |
Pseudovibrio sp. PV1 (α-Proteobacteria) | Unidentified | Antimicrobial | [123] |
Pseudovibrio sp. PV2 ( α-Proteobacteria) | Unidentified | Antimicrobial | [123] |
Pseudovibrio sp. PV4 ( α-Proteobacteria) | Unidentified | Antimicrobial | [123] |
Streptomyces sp. SM1 (Actinobacteria) | Unidentified | Antimicrobial | [123] |
Streptomyces sp. SM2 (Actinobacteria) | Unidentified | Antimicrobial | [123] |
Streptomyces sp. SM3 (Actinobacteria) | Unidentified | Antimicrobial | [123] |
Streptomyces sp. SM4 (Actinobacteria) | Unidentified | Antimicrobial | [123] |
Streptomyces sp. SM5 (Actinobacteria) | Unidentified | Antimicrobial | [123] |
Streptomyces sp. SM6 (Actinobacteria) | Unidentified | Antimicrobial | [123] |
Streptomyces sp. SM7 (Actinobacteria) | Unidentified | Antimicrobial | [123] |
Streptomyces sp. SM8 (Actinobacteria) | Unidentified | Antimicrobial | [123] |
Streptomyces sp. SM9 (Actinobacteria) | Unidentified | Antimicrobial | [123] |
Streptomyces sp. SM10 (Actinobacteria) | Unidentified | Antimicrobial | [123] |
Streptomyces sp. SM11 (Actinobacteria) | Unidentified | Antimicrobial | [123] |
Streptomyces sp. SM12 (Actinobacteria) | Unidentified | Antimicrobial | [123] |
Streptomyces sp. SM14 (Actinobacteria) | Unidentified | Antimicrobial | [123] |
Streptomyces sp. SM16 (Actinobacteria) | Unidentified | Antimicrobial | [123] |
Streptomyces sp. SM17 (Actinobacteria) | Unidentified | Antimicrobial | [123] |
Streptomyces sp. SM18 (Actinobacteria) | Unidentified | Antimicrobial | [123] |
Streptomyces sp. SM19 (Actinobacteria) | Unidentified | Antimicrobial | [123] |
Bacillus sp. BC1 (Firmicutes) | Unidentified | Antimicrobial | [123] |
Bacillus sp. BC2 (Firmicutes) | Unidentified | Antimicrobial | [123] |
|
Haliclona sp. (Tomini Bay, North Sulawesi, Indonesia) | Unidentified fungus | Hirsutanol A | Antibiotic | [123] |
ent-gloeosteretriol | Antibiotic | [123] |
|
Haliclona sp.(North Java Sea, Indonesia) | Unidentified bacterium 1 | Unidentified | Antibacterial | [2] |
Unidentified bacterium 2 | Unidentified | Antibacterial | [2] |
Unidentified bacterium 3 | Unidentified | Antibacterial | [2] |
Unidentified bacterium 4 | Unidentified | Antibacterial | [2] |
Unidentified bacterium 5 | Unidentified | Antibacterial | [2] |
|
Niphatidae | Niphates olemda (Indonesia) | Curvularia lunata (Ascomycota (fungus)) | Lunatin | Antibacterial | [124,125] |
Cytoskyrin A | Antibacterial | [124,125] |
|
Petrosiidae | Petrosia ficiformis (Capo S. Andrea, Elba, Italy) | Penicillium brevicompactum (Ascomycota (fungus)) | Mycophenolic acid | Immuno-suppressant | [128] |
Aspergillus insuetus (Ascomycota (fungus)) | Terretonins E | Inhibit mammalian mitochondrial respiratory chain | [132] |
Terretonins F | Inhibit mammalian mitochondrial respiratory chain | [132] |
|
Petrosia sp. (Jeju Island, Korea) | Aspergillus versicolor (Ascomycota (fungus)) | Decumbenone A | Melanin inhibitor | [139] |
Fellutamide C | Cytotoxic | [140] |
|
Xestospongia sp. (Off Noumea (New Caledonia, southwest Pacific)) | Micrococcus luteus R-1588-10 (Actinobacteria) | 2,4,4′-trichloro-2′-hydroxy-diphenylether (Triclosan) | Antimicrobial | [133] |
Acyl-1-(acyl-6′-mannobiosyl)-3-glycerol (Lutoside) | Antimicrobial | [133] |
|
Xestospongia exigua (Bali Sea, Indonesia) | Penicillium cf. montanense (Ascomycota (fungus)) | Xestodecalactone B | Antifungal | [79,134] |
|
Xestospongia exigua (Indonesia) | Aspergillus versicolor (Ascomycota (fungus)) | Aspergillitine | Antibacterial | [124,135] |
|
Acantho-strongylophora sp. (Indonesia) | Micromonospora sp. (Actinobacteria) | Manzamine A | Antitumor, antimalarial | [82,137, 138] |
|
Order Lithistida Family Neopeltidae | Homophymia sp. (Off Touho, New Caledonia) | Pseudomonas sp. 1537-E7 (γ-Proteobacteria) | 2-undecyl-4-quinolone | Antimalarial Anti HIV | [142] |
2-undecen-1′-yl-4-quinolone | Cytotoxic | [142] |
2-nonyl-4-hydroxy-quinoline N-oxide | Antibacterial, cytotoxic | [142] |
|
Theonellidae | Theonella swinhoei (Palau) | Unidentified bacterium | Swinholide A | Cytotoxic | [144,145] |
Candidatus Entotheonella palauensis (δ-Proteobacteria) | Theopalauamide | Antifungal | [26,144,146] |
|
Theonella swinhoei (Philippines) | Entotheonella palauenis (δ-Proteobacteria) | Theonegramide | Antifungal | [145,147] |
|
Theonella swinhoei (Hachijojima Island, Japan) | Uncultured bacterium | Onnamide A | Antitumor | [149,150] |
|
Order Poecilosclerida Family Acarnidae | Zyzzya sp. (Fiji) | Penicillium brocae (Ascomycota (fungus)) | Brocaenol A | Cytotoxic | [151,152] |
Brocaenol B | Cytotoxic | [151,152] |
Brocaenol C | Cytotoxic | [151,152] |
|
Isodictyidae | Isodictya setifera (Hut Point and Danger Slopes, Ross Island, Antarctica) | Pseudomonas aeruginosa (γ-Proteobacteria) | Cyclo-(L-proline-L-methionine) | Antibacterial | [153] |
|
Raspailiidae | Ectyoplasia ferox (Dominica, Carribean Island) | Coniothyrium sp. 193477 (Deuteromycota (fungus)) | (3S)-(3′,5′-dihydroxyphenyl) butan-2-one | Antimicrobial | [154] |
2-(1′(E)-propenyl)-octa-4(E),6(Z)-diene-1,2-Diol | Antimicrobial | [154] |
(3R) 6-methoxymellein | Antimicrobial | [154] |
(3R)-6-methoxy-7-chloromellein | Antimicrobial | [154] |
Crypto-sporiopsinol | Antimicrobial | [154] |
Phoma sp. (Ascomycota (fungus)) | Epoxyphomalin A | Antitumor | [155] |
Spicellum roseum 193H15 (Deuteromycota (fungus)) | Trichodermol | Anticancer | [156,157] |
8-deoxytrichothecin | Anticancer | [156,157] |
|
Mycalidae | Mycale plumose (Qingdao coast, China) | Saccharopolyspora sp. nov. (Actinobacteria) | Metacyclo-prodigiosin | Anticancer | [159] |
Undecyl-prodigiosin | Anticancer | [159] |
Penicillium auratiogriseum (Ascomycota (fungus)) | (S)-2,4-dihydroxy-1-butyl(4-hydroxy)-benzoate | Antitumor | [160] |
Fructigenin A | Antitumor | [160] |
Aurantiomide B | Cytotoxic | [161] |
Aurantiomide C | Cytotoxic | [161] |
|
Mycale adhaerens | Exophiala pisciphila N110102 (Ascomycota (fungus)) | Exophilin A | Antibacterial | [48,162] |
|
Myxillidae | Myxilla incrustance (Helgoland, Germany) | Microsphaeropsis sp. H5-50 (Anamorphic fungus) | Microsphaeropsisin | Antifungal | [79,154] |
(R)-mellein | Antimicrobial | [154] |
(3R,4S)-hydroxymellein | Antimicrobial | [154] |
(3R,4R)-hydroxymellein | Antimicrobial | [154] |
4,8-dihydroxy-3,4-dihydro-2H-naphthalen-1-one | Antimicrobial | [154] |
|
Order Spirophorida Family Tetillidae | Craniella australiensis (South China Sea) | Streptomyces sp. DA11 (Actinobacteria) | Chitinase | Antifungal | [163] |
|
Order Verongida Family Aplysinellidae | Suberea clavata (Great Barrier Reef, Australia) | Salinospora sp. (Actinobacteria) | Rifamycin B | Antibiotic | [164,166] |
Rifamycin SV | Antibiotic | [164,166] |
|
Aplysinidae | Aplysina aerophoba (Mediterranean coast, France) | Bacillus subtilis A184 (Firmicutes) | Surfactin, iturin and fengycin | Antifungal, antibacterial, hemolytic | [170] |
Bacillus subtilis A190 (Firmicutes) | Surfactin | Antifungal, hemolytic | [170] |
Bacillus subtilis A202 (Firmicutes) | Iturin | Antifungal, hemolytic | [170] |
Bacillus pumilus A586 (Firmicutes) | Pumilacidin containing β-hydroxy fatty-acid | Antibacterial | [170] |
|
Aplysina aerophoba (Mediterranean Sea) | Microsphaeropsis sp. (Anamorphic fungus) | 10-Hydroxy-18-methoxyl-betaenone | Protein Kinase C ɛ inhibitor | [174] |
|
Aplysina aerophoba (Banyuls sur Mer) | Bacillus sp. SB8 (Firmicutes) | Unidentified compound | Antibacterial | [41] |
|
Bacillus sp. SB17 (Firmicutes) | Unidentified compound | Antibacterial | [41] |
Micrococcus sp. SB58 (Actinobacteria) | Unidentified compound | Antibacterial | [41] |
Enterococcus sp. SB91 (Firmicutes) | Unidentified compound | Antibacterial | [41] |
Arthrobacter sp. SB95 (Actinobacteria) | Unidentified compound | Antibacterial | [41] |
Unidentified bacteria SB122 | Unidentified compound | Antibacterial | [41] |
Unidentified bacteria SB144 | Unidentified compound | Antibacterial | [41] |
α-Proteobacteria SB6 | Unidentified compound | Antibacterial | [41] |
α-Proteobacteria SB55 | Unidentified compound | Antibacterial | [41] |
α-Proteobacteria SB63 | Unidentified compound | Antibacterial | [41] |
α-Proteobacteria SB89 | Unidentified compound | Antibacterial | [41] |
α-Proteobacteria SB156 | Unidentified compound | Antibacterial | [41] |
α-Proteobacteria SB197 | Unidentified compound | Antibacterial | [41] |
α-Proteobacteria SB202 | Unidentified compound | Antibacterial | [41] |
α-Proteobacteria SB207 | Unidentified compound | Antibacterial | [41] |
α-Proteobacteria SB214 | Unidentified compound | Antibacterial | [41] |
Vibrio halioticoli SB177 (γ-Proteobacteria) | Unidentified compound | Antibacterial | [41] |
Pseudo-alteromonas sp. SB181 (γ-Proteobacteria) | Unidentified compound | Antibacterial | [41] |
Pseudo-alteromonas sp. SB182 (γ-Proteobacteria) | Unidentified compound | Antibacterial | [41] |
Pseudo-alteromonas sp. SB183 (γ-Proteobacteria) | Unidentified compound | Antibacterial | [41] |
Pseudo-alteromonas sp. SB185 (γ-Proteobacteria) | Unidentified compound | Antibacterial | [41] |
Pseud-oalteromonas sp. SB186 (γ-Proteobacteria) | Unidentified compound | Antibacterial | [41] |
Pseudo-alteromonas sp. SB192 (γ-Proteobacteria) | Unidentified compound | Antibacterial | [41] |
Pseudo-alteromonas sp. SB194 (γ-Proteobacteria) | Unidentified compound | Antibacterial | [41] |
Pseudo-alteromonas sp. SB200 (γ-Proteobacteria) | Unidentified compound | Antibacterial | [41] |
Pseudo-alteromonas sp. SB208 (γ-Proteobacteria) | Unidentified compound | Antibacterial | [41] |
Pseudo-alteromonas sp. SB213 (γ-Proteobacteria) | Unidentified compound | Antibacterial | [41] |
|
Pseudo-ceratinidae | Pseudoceratina purpurea (Fiji) | Metarrhizium sp. 001103 (Ascomycota (fungus)) | Destruxin A | Antitumor | [90] |
Destruxin B2 | Antitumor | [90] |
Desmethyl B | Antitumor | [90] |
E chlorohydrin | Antitumor | [90] |
E2 chlorohydrin | Antitumor | [90] |
|
Class: Calcarea
|
Order Clathrinida Family Leucettidae | Leucetta microraphis (Great Barrier Reef, Australia) | Unidentified cyanobacteria | Leucamide A | Antitumor | [120] |
|
Unidentified sponges
|
Unidentified | Unidentified (Venezuela) | Emericella variecolor (Ascomycota (fungus)) | Varitriol | Anticancer | [176] |
Varixanthone | Antimicrobial | [176] |
|
Unidentified | Streptomyces sp. Ni-80 (Actinobacteria) | Urauchimycin A | Antibiotic | [177] |
Urauchimycin B | Antibiotic | [177] |
|
Unidentified (Harrington Point, Otago Harbor, New Zealand) | Microascus longirostris SF-73 (Ascomycota (fungus)) | Cathestatin A | Cysteine protease inhibitor | [178] |
Cathestatin B | Cysteine protease inhibitor | [178] |
Cathestatin C | Cysteine protease inhibitor | [178] |
|
Unidentified (Pohnpei, The federated state of Micronesia) | Aspergillus ostianus 01F313 (Ascomycota (fungus)) | 8-chloro-9-hydroxy-8,9-deoxyasperlactone | Antibacterial | [179] |
9-chloro-8-hydroxy-8,9-deoxyasperlactone | Antibacterial | [179] |
9-chloro-8-hydroxy-8,9-deoxyaspyrone | Antibacterial | [179] |
Aspinonene | Antileukemic | [48,180] |
Dihydroaspyrone | Antileukemic | [48,180] |
Aspergillide A | Antileukemic | [48,181] |
Aspergillide B | Antileukemic | [48,181] |
Aspergillide C | Antileukemic | [48,181] |
Cryptosphaeria eunomia (Ascomycota (fungus)) | Diaporthein A | Antibacterial | [48,182] |
Diaporthein B | Antibacterial | [48,182] |