Next Article in Journal
Northern Sea Cucumber (Cucumaria frondosa): A Potential Candidate for Functional Food, Nutraceutical, and Pharmaceutical Sector
Previous Article in Journal
Quorum Sensing Inhibitory and Antifouling Activities of New Bromotyrosine Metabolites from the Polynesian Sponge Pseudoceratina n. sp.
Open AccessArticle

Chitosan Oligosaccharide Fluorinated Derivative Control Root-Knot Nematode (Meloidogyne incognita) Disease Based on the Multi-Efficacy Strategy

by Zhaoqian Fan 1,2, Yukun Qin 1,2,*, Song Liu 1,2, Ronge Xing 1,2, Huahua Yu 1,2 and Pengcheng Li 1,2,*
1
Key Laboratory of Experimental Marine Biology, Center for Ocean Mega-Science, Institute of Oceanology, Chinese Academy of Sciences, No. 7 Nanhai Road, Qingdao 266071, China
2
Laboratory for Marine Drugs and Bioproducts, Pilot National Laboratory for Marine Science and Technology (Qingdao), No. 1 Wenhai Road, Qingdao 266237, China
*
Authors to whom correspondence should be addressed.
Mar. Drugs 2020, 18(5), 273; https://doi.org/10.3390/md18050273
Received: 25 April 2020 / Revised: 12 May 2020 / Accepted: 18 May 2020 / Published: 22 May 2020
Plant root-knot nematode disease is a great agricultural problem and commercially available nematicides have the disadvantages of high toxicity and limited usage; thus, it is urgent to develop new nematicides derived from nature substances. In this study, a novel fluorinated derivative was synthesized by modifying chitosan oligosaccharide (COS) using the strategy of multiple functions. The derivatives were characterized by FTIR, NMR, elemental analysis, and TG/DTG. The activity assays show that the derivatives can effectively kill the second instar larvae of Meloidogyne incognita in vitro, among them, chitosan-thiadiazole-trifluorobutene (COSSZFB) perform high eggs hatching inhibitory activity. The derivatives can regulate plant growth (photosynthetic pigment), improve immunity (chitinase and β-1,3-glucanase), and show low cytotoxicity and phytotoxicity. According to the multi-functional activity, the derivatives exhibit a good control effect on plant root-knot nematode disease in vivo. The results demonstrate that the COS derivatives (especially fluorinated derivative) perform multiple activities and show the potential to be further evaluated as nematicides. View Full-Text
Keywords: chitosan oligosaccharide (COS); modification; Meloidogyne incognita; multi-efficacy; nematicide chitosan oligosaccharide (COS); modification; Meloidogyne incognita; multi-efficacy; nematicide
Show Figures

Graphical abstract

MDPI and ACS Style

Fan, Z.; Qin, Y.; Liu, S.; Xing, R.; Yu, H.; Li, P. Chitosan Oligosaccharide Fluorinated Derivative Control Root-Knot Nematode (Meloidogyne incognita) Disease Based on the Multi-Efficacy Strategy. Mar. Drugs 2020, 18, 273.

Show more citation formats Show less citations formats
Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

Article Access Map by Country/Region

1
Search more from Scilit
 
Search
Back to TopTop