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Open AccessCommunication

Microindolinone A, a Novel 4,5,6,7-Tetrahydroindole, from the Deep-Sea-Derived Actinomycete Microbacterium sp. MCCC 1A11207

1
State Key Laboratory Breeding Base of Marine Genetic Resources, Key Laboratory of Marine Genetic Resources, Third Institute of Oceanography, State Oceanic Administration, 184 Daxue Road, Xiamen 361005, China
2
Fujian Key Laboratory of Marine Genetic Resources, South China Sea Bio-Resource Exploitation and Utilization Collaborative Innovation Center, Third Institute of Oceanography, State Oceanic Administration, 184 Daxue Road, Xiamen 361005, China
*
Author to whom correspondence should be addressed.
Mar. Drugs 2017, 15(7), 230; https://doi.org/10.3390/md15070230
Received: 25 May 2017 / Revised: 30 June 2017 / Accepted: 14 July 2017 / Published: 19 July 2017
(This article belongs to the Special Issue Natural Products from Marine Actinomycetes)
A novel indole, microindolinone A (1), was isolated from a deep-sea-derived actinomycete Microbacterium sp. MCCC 1A11207, together with 18 known compounds (219). By detailed analysis of the 1H, 13C, HSQC, COSY, HMBC, high resolution electron spray ionization mass spectrum (HRESIMS), and circular dichroism (CD) data, the absolute configuration of 1 was elucidated as 5R-hydroxy-4,5,6,7-tetrahydroindole-4-one. It is noteworthy that 1 is the second example of a saturated indole isolated from nature. View Full-Text
Keywords: deep-sea; actinomycete; Microbacterium sp.; indole deep-sea; actinomycete; Microbacterium sp.; indole
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MDPI and ACS Style

Niu, S.; Zhou, T.-T.; Xie, C.-L.; Zhang, G.-Y.; Yang, X.-W. Microindolinone A, a Novel 4,5,6,7-Tetrahydroindole, from the Deep-Sea-Derived Actinomycete Microbacterium sp. MCCC 1A11207. Mar. Drugs 2017, 15, 230.

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