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Mar. Drugs 2017, 15(2), 44;

Briarane Diterpenoids Isolated from Octocorals between 2014 and 2016

National Museum of Marine Biology and Aquarium, Pingtung 944, Taiwan
Graduate Institute of Marine Biology, National Dong Hwa University, Pingtung 944, Taiwan
Graduate Institute of Natural Products, College of Medicine, Chinese Herbal Medicine Research Team, Healthy Aging Research Center, Chang Gung University; Research Center for Chinese Herbal Medicine, Research Center for Food and Cosmetic Safety, and Graduate Institute of Health Industry Technology, College of Human Ecology, Chang Gung University of Science and Technology; Department of Anesthesiology, Chang Gung Memorial Hospital, Taoyuan 333, Taiwan
Department of Marine Biotechnology and Resources, National Sun Yat-sen University, Kaohsiung 804, Taiwan
Graduate Institute of Natural Products, Kaohsiung Medical University, Kaohsiung 807, Taiwan
Research Center for Natural Products and Drug Development, Kaohsiung Medical University, Kaohsiung 807, Taiwan
Department of Medical Research, Kaohsiung Medical University Hospital, Kaohsiung 807, Taiwan
Chinese Medicine Research and Development Center, China Medical University Hospital, Taichung 404, Taiwan
Authors to whom correspondence should be addressed.
Academic Editor: Orazio Taglialatela-Scafati
Received: 27 January 2017 / Revised: 14 February 2017 / Accepted: 15 February 2017 / Published: 17 February 2017
Full-Text   |   PDF [1937 KB, uploaded 17 February 2017]   |  


The structures, names, bioactivities, and references of 124 briarane-type natural products, including 66 new metabolites, isolated between 2014 and 2016 are summarized in this review article. All of the briarane diterpenoids mentioned in this review were isolated from octocorals, mainly from Briareum violacea, Dichotella gemmacea, Ellisella dollfusi, Junceella fragilis, Junceella gemmacea, and Pennatula aculeata. Some of these compounds exhibited potential biomedical activities, including anti-inflammatory activity, antibacterial activity, and cytotoxicity towards cancer cells. View Full-Text
Keywords: briarane; octocoral; Briareum; Dichotella; Ellisella; Junceella; Pennatula briarane; octocoral; Briareum; Dichotella; Ellisella; Junceella; Pennatula

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Su, Y.-D.; Su, J.-H.; Hwang, T.-L.; Wen, Z.-H.; Sheu, J.-H.; Wu, Y.-C.; Sung, P.-J. Briarane Diterpenoids Isolated from Octocorals between 2014 and 2016. Mar. Drugs 2017, 15, 44.

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