Bisdioxycalamenene: A Bis-Sesquiterpene from the Soft Coral Rhytisma fulvum fulvum
Abstract
:1. Introduction
2. Results and Discussion
3. Experimental Section
3.1. General Experimental Procedures
3.2. Biological Material
3.3. Isolation Procedure
3.4. X-Ray Crystallography
3.5. Brine Shrimp Toxicity Assay
4. Conclusions
Supplementary Materials
Acknowledgments
Author Contributions
Conflicts of Interest
References
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Position | δC, Type b | δH, Mult (J in Hz) | HMBC Correlations c | COSY Correlations |
---|---|---|---|---|
1 | 27.2, CH | 2.99, ddq (1.3, 6.8, 7.0) | 2, 3, 5, 8, 9, 10, 11 | 2a, 11 |
2 | 25.5, CH2 | 1.84, m | 10 | 1 |
1.46, m | 3a, 3b, 12 | |||
3 | 18.5, CH2 | 1.74, m | 10 | 2b, 3b, 4, 12 |
1.61, m | 4, 10 | 2b, 3a, 4 | ||
4 | 36.9, CH | 2.66, dt (2.3, 6.0) | 2, 3, 5, 9, 10, 12, 14 | 3a, 3b, 12 |
5 | 199.4, qC | |||
6 | 48.0, qC | |||
7 | 83.9, CH | 4.39, s | 5, 6, 8, 9, 15, 5′, 15′ | |
8 | 195.3, qC | |||
9 | 150.3, qC | |||
10 | 147.3, qC | |||
11 | 20.1, CH3 | 1.10, d (7.0) | 1, 2, 9, 10 | 1 |
12 | 31.1, CH | 1.82, m | 3, 4 | 2b, 3a, 4, 13, 14 |
13 | 21.3, CH3 | 0.87, d (7.0) | 4, 12, 14 | 12 |
14 | 20.2, CH3 | 0.85, d (7.0) | 4, 12 | 12 |
15 | 21.8, CH3 | 1.33, s | 5, 6, 7, 6′, 15′ | |
1′ | 26.5, CH | 3.09, dq (6.5,7.0) | 2′, 3′, 8′, 9′, 10′, 11′ | 2′a, 11′ |
2′ | 25.6, CH2 | 1.93, m | 10′ | 1′, 2′b, 3′ |
1.41, m | 4′, 9′ | 3′ | ||
3′ | 19.5, CH2 | 1.70, m | 1′, 4′, 10′, 12′ | 2′a, 2′b, 4′ |
4′ | 37.0, CH | 2.72, dt (2.3, 5.9) | 2′, 5′, 9′, 10′, 12′, 14′ | 1′, 3′, 12′ |
5′ | 144.0, qC | |||
6′ | 115.4, qC | |||
7′ | 107.5, CH | 6.36, s | 5′, 8′, 9′, 15′ | |
8′ | 151.7, qC | |||
9′ | 130.6, qC | |||
10′ | 129.1, qC | |||
11′ | 21.9, CH3 | 1.07, d (7.0) | 1′, 2′, 9′ | 1′ |
12′ | 32.3, CH | 1.86, m | 3′, 10′, 14′ | 4′, 13′, 14′ |
13′ | 21.7, CH3 | 0.86, d (7.0) | 4′, 12′ | 12′ |
14′ | 21.4, CH3 | 0.77, d (7.0) | 4′, 12′ | 12′ |
15′ | 33.1, CH2 | 3.35, d (16.5) | 5, 6, 7, 8, 15, 5′, 6′, 7′, 8′, 9′ | |
2.53, d (16.5) | 5, 6, 7, 15, 5′, 6′, 7′, 8′, 9′, 10′ | |||
16′ | 55.2, CH3 | 3.74, s | 7′, 8′ |
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Trifman, Y.J.; Aknin, M.; Gauvin-Bialecki, A.; Benayahu, Y.; Carmeli, S.; Kashman, Y. Bisdioxycalamenene: A Bis-Sesquiterpene from the Soft Coral Rhytisma fulvum fulvum. Mar. Drugs 2016, 14, 41. https://doi.org/10.3390/md14020041
Trifman YJ, Aknin M, Gauvin-Bialecki A, Benayahu Y, Carmeli S, Kashman Y. Bisdioxycalamenene: A Bis-Sesquiterpene from the Soft Coral Rhytisma fulvum fulvum. Marine Drugs. 2016; 14(2):41. https://doi.org/10.3390/md14020041
Chicago/Turabian StyleTrifman, Yuval J., Maurice Aknin, Anne Gauvin-Bialecki, Yehuda Benayahu, Shmuel Carmeli, and Yoel Kashman. 2016. "Bisdioxycalamenene: A Bis-Sesquiterpene from the Soft Coral Rhytisma fulvum fulvum" Marine Drugs 14, no. 2: 41. https://doi.org/10.3390/md14020041
APA StyleTrifman, Y. J., Aknin, M., Gauvin-Bialecki, A., Benayahu, Y., Carmeli, S., & Kashman, Y. (2016). Bisdioxycalamenene: A Bis-Sesquiterpene from the Soft Coral Rhytisma fulvum fulvum. Marine Drugs, 14(2), 41. https://doi.org/10.3390/md14020041