Next Article in Journal
Strategies to Maximize the Potential of Marine Biomaterials as a Platform for Cell Therapy
Next Article in Special Issue
Novel Azetidine-Containing TZT-1027 Analogues as Antitumor Agents
Previous Article in Journal
Larvicidal Potential of the Halogenated Sesquiterpene (+)-Obtusol, Isolated from the Alga Laurencia dendroidea J. Agardh (Ceramiales: Rhodomelaceae), against the Dengue Vector Mosquito Aedes aegypti (Linnaeus) (Diptera: Culicidae)
Previous Article in Special Issue
In Vitro and in Vivo Anticancer Activity of Pardaxin against Proliferation and Growth of Oral Squamous Cell Carcinoma
Open AccessReview

New Perspectives in the Chemistry of Marine Pyridoacridine Alkaloids

Department of Pharmacy—Center for Drug Research, Ludwig-Maximilians University, Butenandtstr. 5-13, 81377 Munich, Germany
*
Author to whom correspondence should be addressed.
Dedicated to Prof. Dr. Gunther Seitz, Marburg, on the occasion of his 80th birthday
Academic Editor: Patrizia Diana
Mar. Drugs 2016, 14(2), 26; https://doi.org/10.3390/md14020026
Received: 28 November 2015 / Revised: 9 January 2016 / Accepted: 15 January 2016 / Published: 26 January 2016
(This article belongs to the Special Issue Synthesis of Antitumor Marine Alkaloids and Related Analogues)
Secondary metabolites from marine organisms are a rich source of novel leads for drug development. Among these natural products, polycyclic aromatic alkaloids of the pyridoacridine type have attracted the highest attention as lead compounds for the development of novel anti-cancer and anti-infective drugs. Numerous sophisticated total syntheses of pyridoacridine alkaloids have been worked out, and many of them have also been extended to the synthesis of libraries of analogues of the alkaloids. This review summarizes the progress in the chemistry of pyridoacridine alkaloids that was made in the last one-and-a-half decades. View Full-Text
Keywords: marine alkaloids; pyridoacridines; total synthesis marine alkaloids; pyridoacridines; total synthesis
Show Figures

Figure 1

MDPI and ACS Style

Plodek, A.; Bracher, F. New Perspectives in the Chemistry of Marine Pyridoacridine Alkaloids. Mar. Drugs 2016, 14, 26.

Show more citation formats Show less citations formats
Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

Article Access Map

1
Back to TopTop