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Open AccessFeature PaperArticle

Biotechnological Production of Docosahexaenoic Acid Using Aurantiochytrium limacinum: Carbon Sources Comparison And Growth Characterization

Bioengineering Department, IQS, Ramon Llull University, Via Augusta 390, Barcelona 08017, Spain
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Academic Editor: Gilles Barnathan
Mar. Drugs 2015, 13(12), 7275-7284; https://doi.org/10.3390/md13127064
Received: 8 June 2015 / Accepted: 30 November 2015 / Published: 5 December 2015
(This article belongs to the Special Issue Marine Lipids)
Aurantiochytrium limacinum, a marine heterotrophic protist/microalga has shown interesting yields of docosahexaenoic acid (DHA) when cultured with different carbon sources: glucose, pure and crude glycerol. A complete study in a lab-scale fermenter allowed for the characterization and comparison of the growth kinetic parameters corresponding to each carbon source. Artificial Marine Medium (AMM) with glucose, pure and crude glycerol offered similar biomass yields. The net growth rates (0.10–0.12 h−1), biomass (0.7–0.8 g cells/g Substrate) and product (0.14–0.15 g DHA/g cells) yields, as well as DHA productivity were similar using the three carbon sources. Viable potential applications to valorize crude glycerol are envisioned to avoid an environmental problem due to the excess of byproduct. View Full-Text
Keywords: glycerol; biodiesel; DHA; fatty acids; PUFA; omega-3 fatty acids; microalgae; bioprocess; nutraceutics glycerol; biodiesel; DHA; fatty acids; PUFA; omega-3 fatty acids; microalgae; bioprocess; nutraceutics
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Abad, S.; Turon, X. Biotechnological Production of Docosahexaenoic Acid Using Aurantiochytrium limacinum: Carbon Sources Comparison And Growth Characterization. Mar. Drugs 2015, 13, 7275-7284.

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