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Mar. Drugs 2014, 12(8), 4495-4503;

Oxygenated Eremophilane- and Neolemnane-Derived Sesquiterpenoids from the Soft Coral Lemnalia philippinensis

Department of Marine Biotechnology and Resources, National Sun Yat-sen University, Kaohsiung 804, Taiwan
Graduate Institute of Marine Biotechnology and Department of Life Science and Institute of Biotechnology, National Dong Hwa University, Pingtung 944, Taiwan
National Museum of Marine Biology and Aquarium, Pingtung 944, Taiwan
Department of Biotechnology, Kaohsiung Medical University, Kaohsiung 807, Taiwan
Department of Medical Research, China Medical University Hospital, China Medical University, Taichung 404, Taiwan
Graduate Institute of Natural Products, Kaohsiung Medical University, Kaohsiung 807, Taiwan
Author to whom correspondence should be addressed.
Received: 8 April 2014 / Revised: 29 July 2014 / Accepted: 31 July 2014 / Published: 15 August 2014
(This article belongs to the Special Issue Terpenoids of Marine Origin)
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Five sesquiterpene-related metabolites (15), including two new eremophilane-type compounds, philippinlins C and D (1 and 2) and a 4,5-seconeolemnane philippinlin E (3), were isolated from the organic extract of a Taiwanese soft coral Lemnalia philippinensis. The structures of the new metabolites were determined on the basis of extensive spectroscopic analysis and by comparison of NMR data with those of related metabolites. Compound 3 was suggested to be derived from the neolemnane skeleton. View Full-Text
Keywords: Lemnalia philippinensis; eremophilane; neolemnane Lemnalia philippinensis; eremophilane; neolemnane

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Xio, Y.-J.; Su, J.-H.; Tseng, Y.-J.; Chen, B.-W.; Liu, W.; Sheu, J.-H. Oxygenated Eremophilane- and Neolemnane-Derived Sesquiterpenoids from the Soft Coral Lemnalia philippinensis. Mar. Drugs 2014, 12, 4495-4503.

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