Next Article in Journal
Aniquinazolines A–D, Four New Quinazolinone Alkaloids from Marine-Derived Endophytic Fungus Aspergillus nidulans
Next Article in Special Issue
Plastids of Marine Phytoplankton Produce Bioactive Pigments and Lipids
Previous Article in Journal
Antioxidant and Anti-Inflammatory Activities of Barettin
Previous Article in Special Issue
Effect of Grazing-Mediated Dimethyl Sulfide (DMS) Production on the Swimming Behavior of the Copepod Calanus helgolandicus
Article Menu

Export Article

Open AccessArticle
Mar. Drugs 2013, 11(7), 2667-2681;

Production, Characterization, and Antioxidant Activity of Fucoxanthin from the Marine Diatom Odontella aurita

Institute of Hydrobiology, Jinan University, Guangzhou 510632, China
Laboratory for Algae Research and Biotechnology, College of Technology and Innovation, Arizona State University, 7001 E. Williams Field Road, Mesa, AZ 85212, USA
Authors to whom correspondence should be addressed.
Received: 23 April 2013 / Revised: 7 June 2013 / Accepted: 8 July 2013 / Published: 23 July 2013
(This article belongs to the Collection Bioactive Compounds from Marine Plankton)
Full-Text   |   PDF [657 KB, uploaded 24 February 2015]   |  


The production, characterization, and antioxidant capacity of the carotenoid fucoxanthin from the marine diatom Odontella aurita were investigated. The results showed that low light and nitrogen-replete culture medium enhanced the biosynthesis of fucoxanthin. The maximum biomass concentration of 6.36 g L−1 and maximum fucoxanthin concentration of 18.47 mg g−1 were obtained in cultures grown in a bubble column photobioreactor (Ø 3.0 cm inner diameter), resulting in a fucoxanthin volumetric productivity of 7.96 mg L−1 day−1. A slight reduction in biomass production was observed in the scaling up of O. aurita culture in a flat plate photobioreactor, yet yielded a comparable fucoxanthin volumetric productivity. A rapid method was developed for extraction and purification of fucoxanthin. The purified fucoxanthin was identified as all-trans-fucoxanthin, which exhibited strong antioxidant properties, with the effective concentration for 50% scavenging (EC50) of 1,1-dihpenyl-2-picrylhydrazyl (DPPH) radical and 2,2′-Azino-bis(3-ethylbenzthiazoline-6-sulfonic acid (ABTS) radical being 0.14 and 0.03 mg mL−1, respectively. Our results suggested that O. aurita can be a natural source of fucoxanthin for human health and nutrition. View Full-Text
Keywords: Odontella aurita; fucoxanthin; photobioreactor; antioxidant Odontella aurita; fucoxanthin; photobioreactor; antioxidant

Figure 1

This is an open access article distributed under the Creative Commons Attribution License (CC BY 3.0).

Supplementary materials


Share & Cite This Article

MDPI and ACS Style

Xia, S.; Wang, K.; Wan, L.; Li, A.; Hu, Q.; Zhang, C. Production, Characterization, and Antioxidant Activity of Fucoxanthin from the Marine Diatom Odontella aurita. Mar. Drugs 2013, 11, 2667-2681.

Show more citation formats Show less citations formats

Related Articles

Article Metrics

Article Access Statistics



[Return to top]
Mar. Drugs EISSN 1660-3397 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert
Back to Top