Pharmaceuticals 2018, 11(2), 54; https://doi.org/10.3390/ph11020054
Multidirectional Efficacy of Biologically Active Nitro Compounds Included in Medicines
Department of Organic Chemistry, Pharmaceutical Faculty, Poznan University of Medical Sciences, Grunwaldzka 6, 60-780 Poznan, Poland
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Received: 8 May 2018 / Revised: 23 May 2018 / Accepted: 25 May 2018 / Published: 29 May 2018
Abstract
The current concept in searching for new bioactive products, including mainly original active substances with potential application in pharmacy and medicine, is based on compounds with a previously determined structure, well-known properties, and biological activity profile. Nowadays, many commonly used drugs originated from natural sources. Moreover, some natural materials have become the source of leading structures for processing further chemical modifications. Many organic compounds with great therapeutic significance have the nitro group in their structure. Very often, nitro compounds are active substances in many well-known preparations belonging to different groups of medicines that are classified according to their pharmacological potencies. Moreover, the nitro group is part of the chemical structure of veterinary drugs. In this review, we describe many bioactive substances with the nitro group, divided into ten categories, including substances with exciting activity and that are currently undergoing clinical trials. View Full-TextKeywords:
nitro group; nitro compounds; drugs with the nitro group; veterinary medicines with the nitro group
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Olender, D.; Żwawiak, J.; Zaprutko, L. Multidirectional Efficacy of Biologically Active Nitro Compounds Included in Medicines. Pharmaceuticals 2018, 11, 54.
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