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Open AccessArticle

A Study Validating the Estimation of Anterior Chamber Depth and Iridocorneal Angle with Portable and Non-Portable Slit-Lamp Microscopy

1
Department of Ophthalmology, Keio University School of Medicine, Tokyo 160-8582, Japan
2
OUI Inc., Tokyo 160-0022, Japan
3
Yokohama Keiai Eye Clinic, Kanagawa 240-0065, Japan
4
Department of Ophthalmology, Tsurumi University School of Dental Medicine, Kanagawa 230-8501, Japan
5
Department of Preventive Medicine and Public Health, School of Medicine, Keio University, Tokyo 160-8582, Japan
*
Author to whom correspondence should be addressed.
Academic Editors: Zahid Yaqoob and Paola Saccomandi
Sensors 2021, 21(4), 1436; https://doi.org/10.3390/s21041436
Received: 20 January 2021 / Revised: 13 February 2021 / Accepted: 17 February 2021 / Published: 19 February 2021
(This article belongs to the Section Sensing and Imaging)
This study assessed the anterior chamber depth (ACD) and iridocorneal angle using a portable smart eye camera (SEC) compared to the conventional slit-lamp microscope and anterior-segment optical coherence tomography (AS-OCT). This retrospective case-control study included 170 eyes from 85 Japanese patients. The correlation between the ACD evaluations conducted with the SEC and conventional slit-lamp was high (r = 0.814). The correlation between the Van-Herick Plus grade obtained using two devices was also high (r = 0.919). A high kappa value was observed for the Van-Herick Plus grading (Kappa = 0.757). A moderate correlation was observed between the ACD measured using AS-OCT and the slit-lamp image acquired with the conventional slit-lamp microscope and SEC (r = 0.609 and 0.641). A strong correlation was observed between the trabecular-iris angle (TIA) measured using AS-OCT and Van-Herick Plus grade obtained with the conventional slit-lamp microscope and SEC (r = 0.702 and 0.764). Strong correlations of ACD evaluation and high kappa value of the Van-Herick Plus grading indicated the adequate subjective assessment function of the SEC. Moderate correlations between the ACD objective measurement and evaluation and strong correlation between the TIA and Van-Herick Plus grade suggested the good objective assessment function of the SEC. The SEC demonstrated adequate performance for ACD evaluation and angle estimation. View Full-Text
Keywords: smart eye camera; slit-lamp microscope; anterior chamber depth; trabecular-iris angle; anterior-segment optical coherence tomography smart eye camera; slit-lamp microscope; anterior chamber depth; trabecular-iris angle; anterior-segment optical coherence tomography
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MDPI and ACS Style

Shimizu, E.; Yazu, H.; Aketa, N.; Yokoiwa, R.; Sato, S.; Yajima, J.; Katayama, T.; Sato, R.; Tanji, M.; Sato, Y.; Ogawa, Y.; Tsubota, K. A Study Validating the Estimation of Anterior Chamber Depth and Iridocorneal Angle with Portable and Non-Portable Slit-Lamp Microscopy. Sensors 2021, 21, 1436. https://doi.org/10.3390/s21041436

AMA Style

Shimizu E, Yazu H, Aketa N, Yokoiwa R, Sato S, Yajima J, Katayama T, Sato R, Tanji M, Sato Y, Ogawa Y, Tsubota K. A Study Validating the Estimation of Anterior Chamber Depth and Iridocorneal Angle with Portable and Non-Portable Slit-Lamp Microscopy. Sensors. 2021; 21(4):1436. https://doi.org/10.3390/s21041436

Chicago/Turabian Style

Shimizu, Eisuke; Yazu, Hiroyuki; Aketa, Naohiko; Yokoiwa, Ryota; Sato, Shinri; Yajima, Junichiro; Katayama, Taiichiro; Sato, Rio; Tanji, Makoto; Sato, Yasunori; Ogawa, Yoko; Tsubota, Kazuo. 2021. "A Study Validating the Estimation of Anterior Chamber Depth and Iridocorneal Angle with Portable and Non-Portable Slit-Lamp Microscopy" Sensors 21, no. 4: 1436. https://doi.org/10.3390/s21041436

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