Highly Sensitive Micropatterned Interdigitated Electrodes for Enhancing the Concentration Effect Based on Dielectrophoresis
Abstract
:1. Introduction
2. Materials and Methods
2.1. Chemicals and Reagents
2.2. Simulation to Calculate Profiles of the Electric Field Between the Electrodes
2.3. Fabrication of IMEs and Immobilization of Antibody
2.4. Sysnthesis of Au Labeled Secondary Antibody
2.5. Image Measurement
2.6. Immunoassay and Signal Processing
3. Results and Discussion
3.1. Enhancing the Intensity of the Electric Field
3.2. Optimizing the Intensity of the DEP Force
3.3. Verifying the Optimal DEP Force
3.4. Enhancing the Sensitivity in the Patterned IMEs
4. Conclusions
Supplementary Materials
Author Contributions
Funding
Conflicts of Interest
References
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Kim, H.J.; Ahn, H.; Lee, D.S.; Park, D.; Kim, J.H.; Kim, J.; Yoon, D.S.; Hwang, K.S. Highly Sensitive Micropatterned Interdigitated Electrodes for Enhancing the Concentration Effect Based on Dielectrophoresis. Sensors 2019, 19, 4152. https://doi.org/10.3390/s19194152
Kim HJ, Ahn H, Lee DS, Park D, Kim JH, Kim J, Yoon DS, Hwang KS. Highly Sensitive Micropatterned Interdigitated Electrodes for Enhancing the Concentration Effect Based on Dielectrophoresis. Sensors. 2019; 19(19):4152. https://doi.org/10.3390/s19194152
Chicago/Turabian StyleKim, Hye Jin, Heeju Ahn, David S. Lee, Dongsung Park, Jae Hyun Kim, Jinsik Kim, Dae Sung Yoon, and Kyo Seon Hwang. 2019. "Highly Sensitive Micropatterned Interdigitated Electrodes for Enhancing the Concentration Effect Based on Dielectrophoresis" Sensors 19, no. 19: 4152. https://doi.org/10.3390/s19194152